302 results match your criteria: "La Conception University Hospital[Affiliation]"

Peritoneal closure reduces port site metastases: results of an experiment in a rat ovarian cancer model.

Surg Endosc

February 2002

Department of Obstetrics and Gynecology, La Conception University Hospital, 147 Boulevard Baille, 13005, Marseille, France.

Background: The arm of this study was to assess the role of peritoneal closure in the prevention of port site metastasis after carbon dioxide (CO2) CO2 pneumoperitoneum.

Methods: We developed a xenograft ovarian cancer model by intraperitoneal injection of 27 106 IGR-OV1 line cells in nude rats Seven days after the inoculation, the animals underwent a CO2 pneumoperitoneum. At the end of the procedure, port sites were randomly closed either with suture of peritoneum (n = 14, group A) or without suture of peritoneum (n = 12, group B).

View Article and Find Full Text PDF

Impact of different gases and pneumoperitoneum pressures on tumor growth during laparoscopy in a rat model.

Surg Endosc

March 2002

Department of Obstetrics and Gynecology, La Conception University Hospital, Marseille, 147 Boulevard Baille, 13385 Cedex 05, France.

Background: The influence on intraperitoneal tumor growth of the choice of gas and pneumoperitoneum pressure during laparoscopy is still unknown. This study compared tumor growth after laparoscopy with different gases and pneumoperitoneum pressures in an immunodeficient model.

Methods: In an initial experiment, 60 nude rats were randomly allocated to undergo laparoscopy at different pneumoperitoneum pressures (gasless, 4 mmHg, or 8 mm Hg.

View Article and Find Full Text PDF