Acromioclavicular Joint Injuries: Multi-center Expert Consensus Study using the Delphi Method.

Introduction: Acromioclavicular (AC) joint injuries pose significant challenges in clinical management, necessitating consensus guidelines for optimal treatment. There is a lack of consensus in several areas, including imaging protocols, surgical techniques, and rehabilitation timelines. This study aims to develop a consensus regarding the diagnosis, treatment, and rehabilitation of AC joint separations.

Neoadjuvant Chemotherapy for Newly Diagnosed, Advanced Ovarian Cancer: ASCO Guideline Update.

Purpose: To provide updated guidance regarding neoadjuvant chemotherapy (NACT) and primary cytoreductive surgery (PCS) among patients with stage III-IV epithelial ovarian, fallopian tube, or primary peritoneal cancer (epithelial ovarian cancer [EOC]).

Methods: A multidisciplinary Expert Panel convened and updated the systematic review.

Results: Sixty-one studies form the evidence base.

New and species (Pleosporales, Ascomycota) from spp. in China.

Saprobic fungi are known for their critical role in decomposition and nutrient cycling. The study of saprobic fungi is equally important, as it helps in understanding their ecological roles and identifying their hidden diversity. This study focused on saprobic fungi on , which is poorly studied compared to economically important hosts like coffee, tea, and rubber.

A Mixed Method Evaluation of Practitioners' Perspectives on Implementation Strategies for Healthy Eating and Active Living Policy, Systems, and Environmental Changes.

Context: The National Cooperative Extension System is a leader in delivering healthy eating and active living (HEAL) policy, systems, and environmental (PSE) changes; however, these interventions are challenging, and technical assistance efforts often misalign with implementation science concepts.

Objective: The study objective was to understand the importance of implementation strategies and tailoring needs to support Louisiana Nutrition and Community Health (NCH) practitioners' delivery of rural HEAL PSE changes.

Design: An explanatory sequential mixed method study design was used, including a survey to rank the importance of implementation strategies for HEAL PSE changes and a follow-up interview.

Activation and evasion of inflammasomes during viral and microbial infection.

The inflammasome is a cytoplasmic multiprotein complex that induces the maturation of the proinflammatory cytokines interleukin-1β (IL-1β) and interleukin-18 (IL-18) or pyroptosis by activating caspases, which play critical roles in regulating inflammation, cell death, and various cellular processes. Multiple studies have shown that the inflammasome is a key regulator of the host defence response against pathogen infections. During the process of pathogenic microbe invasion into host cells, the host's innate immune system recognizes these microbes by activating inflammasomes, triggering inflammatory responses to clear the microbes and initiate immune responses.

A multi-modal dental dataset for semi-supervised deep learning image segmentation.

In response to the increasing prevalence of dental diseases, dental health, a vital aspect of human well-being, warrants greater attention. Panoramic X-ray images (PXI) and Cone Beam Computed Tomography (CBCT) are key tools for dentists in diagnosing and treating dental conditions. Additionally, deep learning for tooth segmentation can focus on relevant treatment information and localize lesions.

N, N-dimethyltryptamine (DMT) in rodent brain: Concentrations, distribution, and recent pharmacological data.

Renewed interest in the clinical use of psychedelic drugs acknowledges their therapeutic effectiveness. It has also provided a changing frame of reference for older psychedelic drug study data, especially regarding concentrations of N, N-dimethyltryptamine (DMT) reported in rodent brains and recent discoveries in DMT receptor interactions in rat brain neurons and select brain areas. The mode of action of DMT in its newly defined role as a neuroplastogen, its effectiveness in treating neuropsychiatric disorders, and its binding to intracellular sigma-1 and 5HT2a receptors may define these possible roles.

Novel and (Tubeufiaceae, Tubeufiales) species from terrestrial habitats in China and Thailand.

During our investigations of saprobic fungi, five fungal collections from terrestrial habitats in China and Thailand were examined using both morphological and multi-gene phylogenetic approaches (LSU, ITS, 1-α, and 2), resulting in the identification of three novel species: , , and . and are morphologically similar in their asexual morphs but can be distinguished based on their molecular phylogenetic data. In this study, our new species, , represents the fourth sexual species within the genus, characterized by yellow-brown ascomata and fusiform ascospores.

, a new genus and species in (, ) from western Norway.

The new genus and species are described from dead wood of in western Norway. Despite some morphological resemblance with , including low ascomata with a thick carbonized peridium and mainly five-septate ascospores, multigene analysis of the five molecular markers SSU, ITS, LSU, and revealed an affinity to . The new species formed a strongly supported sister clade to the remaining strains of .

A phylogenetic assessment of in (, ): introduction of new genera, and the resurrection of .

During entomopathogenic fungal surveys conducted in Thailand, 15 specimens tentatively classified under were identified. To gain a comprehensive understanding of their taxonomy, molecular phylogenies using combined LSU, , , and sequence data, together with morphological examination of several spp. from previous studies were conducted.

Meristematic and meristematic-like fungi in .

Meristematic fungi are mainly defined as having aggregates of thick-walled, melanised cells enlarging and reproducing by isodiametric division. black meristematic and meristematic-like fungi have been allied to , which currently has two accepted families, and , with fungi mainly regarded as pathogens, parasites, saprobes and epiphytes of different plant species. This study aimed to verify the phylogenetic position using four nuclear markers (SSU, LSU, ITS and ) of the genera associated with , namely , , and , and the new genus, .

Uncovering cryptic species diversity of () associated with from Thailand.

This study advances our understanding of , an extensively studied entomopathogenic fungus within the , particularly in Thailand. We introduce seven novel species associated with - , , , , , , and . Remarkably, , , and exhibit ascomata on the subterminal region of the stromata, with the asexual form appearing at the apex of the stipe, reminiscent of .

Fungal Planet description sheets: 1697-1780.

Novel species of fungi described in this study include those from various countries as follows: , from accumulated snow sediment sample. , on leaf spots of . , on submerged decaying wood in sea water, on , as endophyte from healthy leaves of .

Taxonomy and phylogeny of three rust fungi parasitic on in Korea, with . on .

Rust fungi are important pathogens of trees, ornamental plants, and food crops. Field research targeting rust diseases across Korea uncovered three distinct species of , affecting different members of the family . In our examination of both wild and cultivated grapevine () species, including , , and , we found as well as a previously undescribed rust species, which we describe here as , which was previously identified as a rust pathogen of spp.

Bayesian Mediation Analysis for Time-to-Event Outcome: Investigating Racial Disparity in Breast Cancer Survival.

Mediation analysis is conducted to make inferences on effects of mediators that intervene the relationship between an exposure variable and an outcome. Bayesian mediation analysis (BMA) naturally considers the hierarchical structure of the effects from the exposure variable to mediators and then to the outcome. We propose three BMA methods on survival outcomes, where mediation effects are measured in terms of hazard rate, survival time, or log of survival time respectively.

Preservation of sexual function with Optilume-a novel treatment for lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Background: The Optilume benign prostatic hyperplasia (BPH) catheter system is a novel minimally invasive paclitaxel-coated dilation system that has demonstrated substantial and durable results in urinary flow and symptoms.

Aim: We now assess the impact of Optilume BPH procedure on sexual function.

Methods: Prior published results have described the methods of data collection during the PINNACLE study, which demonstrated durable improvement in urinary symptoms.

Metabarcoding reveals high species diversity of Chaetoceros, Pseudo-nitzschia, and Thalassiosira in Hong Kong coastal waters, a typical subtropical region.

Chaetoceros, Pseudo-nitzschia, and Thalassiosira are ecologically important genera which formed blooms frequently in Hong Kong coastal waters in past decades. However, species identification based on microscopic observation for diatoms in these genera is difficult. In this study, we investigated species diversity of Chaetoceros, Pseudo-nitzschia, and Thalassiosira in Hong Kong coastal waters using metabarcoding approach.

First report of causing winged leaf dieback disease on in Yunnan Province, China.

Rhus chinensis, a deciduous tree of the genus Rhus (family Anacardiaceae), is widely cultivated in China for its medicinal, edible, and ornamental value (Zhang et al., 2022). In April 2022, symptoms of winged leaf dieback disease were observed at Southwest Forestry University in Kunming, Yunnan Province, China (E102°45'42.

First Report of Causing Root Rot on Tulip Poplar in Tennessee and the United States.

Tulip poplar () is a member of the Magnolia family, is a large, fast-growing, long-lived, deciduous tree native to eastern North America. One-year-old tulip poplar seedlings grown under field conditions in a commercial nursery in Warren County, Tennessee, exhibited severe root rot in May 2024. Dark brown to black lesions were observed on the affected roots.

Vehicle-induced air pollutant dispersion and personal exposure in an urban street canyon: Association with air-source heat pump outdoor units combined with building envelope components.

Air-source heat pumps are popular in buildings to provide cooling and heating. However, how the air discharged by air-source heat pump outdoor units affects the dispersion of air pollutants in urban street canyons remains poorly understood. This study used coupled simulations to examine the effects that air-source heat pump outdoor units had on vehicle-induced indoor and outdoor air pollution in an urban street canyon and how these effects varied based on the arrangement of outdoor units or the presence of building envelope components (e.

New species and records of (Botryosphaeriales, Botryosphaeriaceae) from in China.

During the fungal investigations of hosts in China, ten isolates of were obtained from dead and dying branches. Morphological characteristics and phylogenetic analyses of combined ITS, LSU, and loci revealed the presence of two new species, and , as well as two new host records for and from . In this study, we provide descriptions and illustrations of these species, thereby enriching the diversity within the taxa.

Transseptal BATMAN Procedure Utilizing a Simplified Technique: "Single Wire Approach for Traversing Tissue" (SWATT).

One of the major issues encountered in patients undergoing evaluation for Transcatheter mitral valve replacement (TMVR) is the risk of Left ventricular outflow tract (LVOT) obstruction. LVOT obstruction is a catastrophic complication of TMVR, the result of displacement of the anterior mitral valve leaflet (AML) toward the interventricular septum. Several strategies to mitigate the risk of LVOT obstruction have been described and include percutaneous laceration of the anterior mitral leaflet (LAMPOON), alcohol septal ablation, trans-atrial leaflet modification (SITRAL) and Balloon Assisted Translocation of Mitral Anterior leaflet to prevent LVOT obstruction (BATMAN).

Deceptive illusory cues can influence orthogonally directed manual length estimations.

We examined participants' abilities to manually estimate one of two perpendicular line segment lengths using curved point-to-point movements. Configurations involved symmetrical, unsymmetrical, and no bisection in upright and rotated orientation alterations to vertical-horizontal (V-H) illusions, where people often perceive longer vertical than horizontal segments for equal segment lengths. Participants used two orthogonally directed movements for length estimations: positively proportional (POS) - where greater fingertip displacement involved longer length estimation between configuration intersection start position and fingertip end, and negatively proportional (NEG) - where greater fingertip displacement from the screen edge start position toward configuration intersection involved a shorter length estimation between configuration intersection and fingertip end.

Video versus Direct Laryngoscopy for Tracheal Intubation Following Cardiac Arrest: a Secondary Analysis of the DEVICE Trial.

Background: Airway management is a critical component of the care of patients experiencing cardiac arrest, but data from randomized trials on the use of video vs direct laryngoscopy for intubation in the setting of cardiac arrest are limited. Current AHA guidelines recommend placement of an endotracheal tube either during CPR or shortly after return of spontaneous circulation but do not provide guidance around intubation methods, including the choice of laryngoscope.

Research Question: Does use of video laryngoscopy improve the incidence of successful intubation on the first attempt, compared to use of direct laryngoscopy, among adults undergoing tracheal intubation after experiencing cardiac arrest?

Study Design And Methods: This secondary analysis of the Direct versus Video Laryngoscope (DEVICE) trial compared video laryngoscopy versus direct laryngoscopy in the subgroup of patients who were intubated following cardiac arrest.

Intravaginal cooling provides symptom relief in women with vulvovaginal candidiasis and reduces immunopathology in an accompanying mouse model.

Background: Vulvovaginal candidiasis (VVC), caused primarily by Candida albicans, is currently treated with either prescription or over-the-counter antifungal drugs, often with variable efficacy and relapses. New and improved therapeutic strategies, including drug-free treatment alternatives, are needed. Upon overgrowth or environmental triggers, C.