5 results match your criteria: "LSTM Research Unit at the Centre for Research in Infectious Diseases (CRID)[Affiliation]"

Article Synopsis
  • - Improved tools like DNA barcoding reveal that mosquitoes, specifically malaria vectors in Kenya, feed on plants much more than previously thought, with a 41% feeding rate versus a low 2.8% through traditional methods.
  • - The study found that the presence of the malaria parasite Plasmodium falciparum affects the sugar levels in mosquitoes, and that these insects primarily feed on acacia plants, particularly Vachellia tortilis.
  • - The findings point to the important role of nutrient content and scent from plants in attracting mosquitoes, and these insights could help develop effective strategies for controlling malaria through odor-based traps and bait.
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Outdoor biting by anopheline mosquitoes is one of the contributors to residual malaria transmission, but the profile of vectors driving this phenomenon is not well understood. Here, we studied the bionomics and genetically characterized populations of An. gambiae and An.

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Metabolic resistance to insecticides threatens malaria control. However, little is known about its fitness cost in field populations of malaria vectors, thus limiting the design of suitable resistance management strategies. Here, we assessed the association between the glutathione -transferase GSTe2-mediated metabolic resistance and life-traits of natural populations of .

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Article Synopsis
  • * Researchers found that metabolic resistance, driven mainly by the overexpression of cytochrome P450 and glutathione S-transferase (GST) genes, significantly contributes to this resistance, with the GSTe2 gene showing particularly high upregulation.
  • * The findings suggest that incorporating new control methods like piperonyl butoxide (PBO) with pyrethroid insecticides could be an effective strategy to manage the increasing insecticide resistance in the region.
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Background: Malaria vectors are increasingly developing resistance to insecticides across Africa. The impact of such resistance on the continued effectiveness of insecticide-based interventions remains unclear due to poor characterization of vector populations. This study reports the characterization of malaria vectors at Mibellon, a selected site in Cameroon for experimental hut study, including species composition, Plasmodium infection rate, resistance profiles and mechanisms.

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