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Introduction: End-stage renal disease patients have impaired health-related quality of life as compared to the general population due to the combined effects of the disease and hemodialysis (HD) therapy. As a result, poor quality of life increases their risk of mortality and hospitalization and affects their general well-being. While existing rehabilitation programs aim to improve physical activity in HD patients, the link between work status, particularly within the first year of treatment, and their quality of life remains unclear.

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