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Pediatr Res
October 1999
Division of Neonatal-Perinatal Medicine, Schneider Children's Hospital, LIJMC--The Long Island Campus for the Albert Einstein College of Medicine, New Hyde Park, New York 11040, USA.
The mechanism by which dexamethasone (DEX) inhibits neutrophil (PMN) recruitment to a site of inflammation, such as the newborn lung with bronchopulmonary dysplasia, is not completely understood. The aim of our study was to determine whether DEX inhibits neutrophil-induced neutrophil recruitment by inhibition of interleukin- (IL) 8 release from PMNs, and if there are developmental differences. PMNs isolated from cord blood (CB) and adults (A) were studied.
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