African vital force and the permissibility of euthanasia.

One argument for the permissibility of euthanasia found in the African philosophical tradition suggests that the sole goal of life is to develop one's vital force, which is done by relating harmoniously with one's community. However, this is impossible for people with certain medical conditions. If the goals of life cannot be achieved, then euthanasia is permissible.

Secondary thalamic atrophy related to brain infarction may contribute to post-stroke cognitive impairment.

Background And Purpose: The thalamus is a key brain hub that is globally connected to many cortical regions. Previous work highlights thalamic contributions to multiple cognitive functions, but few studies have measured thalamic volume changes or cognitive correlates. This study investigates associations between thalamic volumes and post-stroke cognitive function.

Future minds are not a challenge to anti-natalism: A reply to Gould.

Deke Caiñas Gould (2021) argues that the possibility of future non-human-like minds who are not harmed by coming into existence poses a challenge to David Benatar's well-known Asymmetry Argument for anti-natalism. Since the good of these future minds has the potential to outweigh the current harms of human existence, they can be appealed to in order to justify procreation. I argue that Gould's argument rests on a fundamental misunderstanding of Benatar's argument.

Office- and Bedside-based Screening for Cognitive Impairment and the Dementias: Which Tools to Use, Interpreting the Results, and What Are the Next Steps?

Elderly patients and their families are concerned about the patients' cognitive abilities, and cognitive screening is an efficient diagnostic tool, as long as clinicians administer the screens in a standardized manner and interpret the screen results accurately. The following brief summary reviews commonly used screening instruments and provides information about how to interpret screening test results. It concludes by showing how cognitive screening fits into a four-step process (Education, Screening, Follow-up, and Referral) of how to respond to patients with cognitive concerns.

Problematising reality: the promises and perils of synthetic media.

This commentary article focuses on the emergence of synthetic media-computer-generated content that is created by employing Artificial Intelligence (AI) technologies. It discusses three of the most notable current forms of this emerging form of content: deepfakes, virtual influencers, and augmented and virtual reality (collectively known as extended reality). Their key features are introduced, and the main challenges and opportunities associated with the technologies are analysed.

Teaching Metabolism in Upper-Division Undergraduate Biochemistry Courses using Online Computational Systems and Dynamical Models Improves Student Performance.

Understanding metabolic function requires knowledge of the dynamics, interdependence, and regulation of metabolic networks. However, multiple professional societies have recognized that most undergraduate biochemistry students acquire only a surface-level understanding of metabolism. We hypothesized that guiding students through interactive computer simulations of metabolic systems would increase their ability to recognize how individual interactions between components affect the behavior of a system under different conditions.

Interactive learning modules with 3D printed models improve student understanding of protein structure-function relationships.

Ensuring undergraduate students become proficient in relating protein structure to biological function has important implications. With current two-dimensional (2D) methods of teaching, students frequently develop misconceptions, including that proteins contain a lot of empty space, that bond angles for different amino acids can rotate equally, and that product inhibition is equivalent to allostery. To help students translate 2D images to 3D molecules and assign biochemical meaning to physical structures, we designed three 3D learning modules consisting of interactive activities with 3D printed models for amino acids, proteins, and allosteric regulation with coordinating pre- and post-assessments.

Does Enrichment Improve Well Being in Animals under Human Care? A Case Study of Two Harbor Seals (Phoca Vitulina).

Harbor seals in the wild live in a stimulating environment; therefore, nonhuman-animal caretakers have increasingly been using environmental enrichment to improve the well being of seals under human care. The purpose of this study was to evaluate an object-based environmental enrichment program during a four-month period on stimulating exploration and play and improving conspecific social interactions and human-animal relationships (HAR). Zoo staff conducted the environmental enrichment program as part of the animal care program.

"A different atmosphere of love": a qualitative study of the experiences of participants in Evangelical substance user rehabilitation programs in the Russian Federation.

This article explores the lived experiences of individuals who have participated in faith-based substance user rehabilitation programs in the Russian Federation. The Russian Federation has high rates of alcohol and opioid dependence and a dearth of professional treatment options. In the post-Soviet period, Evangelical Christian groups have developed substance user rehabilitation programs to attempt to address substance use and its related problems.