Reduction by 98% in uterine myoma volume associated with significant symptom relief after peripheral treatment with magnetic resonance imaging-guided focused ultrasound surgery.

Magnetic resonance imaging-guided focused ultrasound surgery is a noninvasive treatment for symptomatic uterine myomas. Previous studies have demonstrated a correlation between the treated volume of the myoma, improvement in symptoms, and lesion shrinkage. We report a case in which MRgFUS treatment only at the periphery of the myoma resulted in a 98% reduction in tumor volume at 8 months posttreatment, and at 12-month follow-up, only a small lesion was visible at magnetic resonance imaging.

The neural basis of moral cognition: sentiments, concepts, and values.

The human moral nature has perplexed laymen and academics for millennia. Recent developments in cognitive neuroscience are opening new venues for unveiling the complex psychological and neurobiological mechanisms underling human morality and its impairments. Here we review these lines of evidence and key topics of debate and explain why investigating the mechanisms of cognition-emotion interaction and of the neural bases of moral sentiments and values will be critical for our understanding of the human moral mind.

Psychopathy as a disorder of the moral brain: fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry.

Major advances have been made in the understanding of the neurobiology of psychopathy in the past years, yet the distribution and extent of neuroanatomical abnormalities underlying the disorder are still poorly known. It is also unclear if different dimensions of the construct of psychopathy (e.g.

Moral judgments, emotions and the utilitarian brain.

The investigation of the neural and cognitive mechanisms underlying the moral mind is of paramount importance for understanding complex human behaviors, from altruism to antisocial acts. A new study on patients with prefrontal damage provides key insights on the neurobiology of moral judgment and raises new questions on the mechanisms by which reason and emotion contribute to moral cognition.