6 results match your criteria: "Kyushu University Faculty of Medicine Graduate School of Medical Sciences School of Medicine[Affiliation]"
The T2-FLAIR mismatch sign in glioblastoma, isocitrate dehydrogenase wild-type A case report.
Acta Radiol Open
June 2023
Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
We present a case of the T2-FLAIR mismatch sign in glioblastoma, )-wild type. The T2-FLAIR mismatch sign is known as a highly specific imaging finding of astrocytoma, -mutant. Meanwhile, -wildtype diffuse astrocytic gliomas with () promoter mutation in adults are defined as glioblastoma in the 2021 World Health Organization Classification of Tumors of the Central Nervous System, fifth edition (2021 WHO classification), which underscores the importance of molecular information in central nervous system tumors.
View Article and Find Full Text PDFRiociguat inhibits ultra-large VWF string formation on pulmonary artery endothelial cells from chronic thromboembolic pulmonary hypertension patients.
Pulm Circ
October 2022
Department of Pulmonary Medicine, Amsterdam UMC VU University Medical Center Amsterdam The Netherlands.
Article Synopsis
- - Chronic thromboembolic pulmonary hypertension (CTEPH) involves high blood pressure in the lungs due to blood clots, and riociguat is a drug used for patients who can't undergo surgery or have leftover symptoms after surgery.
- - This study investigates how riociguat affects the interaction between platelets (blood cells that help with clotting) and endothelial cells (cells lining blood vessels) in CTEPH patients, particularly looking at its impact on hemostasis (the process of stopping bleeding).
- - Results showed that riociguat reduced platelet adhesion and the formation of von Willebrand Factor (VWF) strings, a key factor for platelet adhesion, possibly due to decreased P-selectin expression on
Radiation Emergency Medical Preparedness in Japan: A Survey of Nuclear Emergency Core Hospitals.
Disaster Med Public Health Prep
February 2022
Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Article Synopsis
- - The study examined the status of Nuclear Emergency Core Hospitals (NECHs) in Japan, which were established for radiation disaster management following the 2011 Great East Japan Earthquake and nuclear accident.
- - Conducted in October 2018, the research involved 36 hospitals and revealed that only 31% had plans for a radiation disaster, highlighting the need for improved business continuity and risk communication strategies.
- - Key areas for healthcare improvement were identified, including media responses, internal communications, regional planning, and addressing public rumors during radiation emergencies.
Optimal timing of surgery in infants with prenatally diagnosed isolated left-sided congenital diaphragmatic hernia: a multicenter, cohort study in Japan.
Surg Today
June 2021
Department of Pediatric Surgery, Osaka University School of Medicine Graduate School of Medicine, Osaka, Japan.
Purpose: To date, there is no compelling evidence of the optimal timing of surgery for congenital diaphragmatic hernia (CDH). This study aimed to establish the optimal timing of surgery in neonates with isolated left-sided CDH.
Methods: This multicenter cohort study enrolled 276 patients with isolated left-sided CDH at 15 institutions.
Global Outcome Assessment Life-long after stroke in young adults initiative-the GOAL initiative: study protocol and rationale of a multicentre retrospective individual patient data meta-analysis.
BMJ Open
November 2019
Department of Neurology, Radboudumc, Nijmegen, The Netherlands.
Introduction: Worldwide, 2 million patients aged 18-50 years suffer a stroke each year, and this number is increasing. Knowledge about global distribution of risk factors and aetiologies, and information about prognosis and optimal secondary prevention in young stroke patients are limited. This limits evidence-based treatment and hampers the provision of appropriate information regarding the causes of stroke, risk factors and prognosis of young stroke patients.
View Article and Find Full Text PDFLeft Ventricular Noncompaction with Multiple Thrombi in Apical Aneurysm.
Intern Med
February 2020
Department of Cardiovascular Medicine, Kyushu University Faculty of Medicine Graduate School of Medical Sciences School of Medicine, Japan.
A 44-year-old man was admitted to our hospital due to heart failure. Transthoracic echocardiography demonstrated global hypokinesis with an ejection fraction of 25%, prominent trabeculation and deep intertrabecular recesses, and apical aneurysm with multiple thrombi (10×13 mm in the inferior wall, 15×8 mm in the anterior wall). Cardiac magnetic resonance imaging showed an increased ratio of noncompacted (NC) to compacted (C) myocardium (NC/C ratio >2.
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