2 results match your criteria: "Kyushu International Heavy Particle Beam Cancer Radiotherapy Center (SAGA HIMAT Foundation)[Affiliation]"
Retrospective Analysis of INRG Clinical and Genomic Factors for 605 Neuroblastomas in Japan: A Report from the Japan Children's Cancer Group Neuroblastoma Committee (JCCG-JNBSG).
Biomolecules
December 2021
Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama 362-0806, Japan.
Article Synopsis
- - The study focused on validating the International Neuroblastoma Risk Group (INRG) prognostic and genomic markers in a Japanese cohort by analyzing data from 605 neuroblastoma cases diagnosed between 1990 and 2014.
- - Key findings showed that certain factors, such as age, tumor stage, and specific genomic patterns, were linked to lower survival rates, especially in stage 4 non-amplified tumors.
- - The researchers concluded that combining genomic patterns with clinical factors like age and LDH levels could serve as an effective predictor for non-amplified high-risk neuroblastoma patients, aligning with previous INRG project findings.
UNC5 dependence receptor family in human cancer: A controllable double-edged sword.
Cancer Lett
September 2021
Kyushu International Heavy Particle Beam Cancer Radiotherapy Center (SAGA HIMAT Foundation), Tosu, Japan. Electronic address:
UNC5 receptor family (UNC5A-D) have been identified as dependence receptors whose functions depend on the availability of their ligand netrin-1. Through binding to netrin-1, these receptors transmit signals for cell survival, migration and differentiation, and participate in diverse physiological and pathological processes. In the lack of netrin-1, however, these receptors initiate apoptosis-inducing signal.
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