2 results match your criteria: "Kyungpook National University Hospital 130 Dongdeok-ro[Affiliation]"
Endogenous inspired biomineral-installed hyaluronan nanoparticles as pH-responsive carrier of methotrexate for rheumatoid arthritis.
J Control Release
April 2017
Division of Rheumatology, Department of Internal Medicine, Kyungpook National University Hospital 130 Dongdeok-ro, Junggu, Daegu 41944, Republic of Korea; Cell and Matrix Research Institute, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea; Department of Biochemistry and Cellular Biology, Kyungpook National University School of Medicine, Daegu 700-422, Republic of Korea. Electronic address:
Methotrexate (MTX), an anchor drug for rheumatoid arthritis (RA), has been suffered from refractoriness and high toxicity limiting effective dosage. To mitigate these challenges, the ability to selectively deliver MTX to arthritis tissue is a much sought-after modality for the treatment of RA. In this study, we prepared mineralized nanoparticles (MP-HANPs), composed of PEGylated hyaluronic acid (P-HA) as the hydrophilic shell, 5β-cholanic acid as the hydrophobic core, and calcium phosphate (CaP) as the pH-responsive mineral.
View Article and Find Full Text PDFExpression of Id-1 and VEGF in non-small cell lung cancer.
Int J Clin Exp Pathol
June 2014
Department of Pathology, Kyungpook National University Hospital 130 Dongdeok-ro, Jung-gu, Deagu, South Korea.
Angiogenesis is essential for invasive tumor growth and metastasis. Bevacizumab has been widely used for the treatment of non-small cell lung cancer (NSCLC). Various studies clearly demonstrate the relevance of Id-1 and VEGF in angiogenesis.
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