1,058 results match your criteria: "Kyungpook National University Chilgok Hospital[Affiliation]"
Biomed Pharmacother
December 2024
Department of Biology, College of Natural Sciences, Kyungpook National University, Daegu 41566, Republic of Korea; School of Life Sciences, BK21 plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Republic of Korea. Electronic address:
mPTP is a multi-protein complex that opens in mitochondria during cell death. Cisplatin-induced hearing loss is also known to be caused by mPTP opening. Thus, our study evaluated the protective effect of a novel mPTP inhibitor named DBP-iPT against cisplatin-induced hearing loss.
View Article and Find Full Text PDFJ Vasc Surg
December 2024
Division of Vascular Surgery, Seoul National University College of Medicine, Seoul, Korea. Electronic address:
Objective: Popliteal artery entrapment syndrome (PAES) results from an anomalous relationship between the popliteal artery and the myofascial structures of the popliteal fossa. The long-term treatment outcomes are not well known because of the rarity of the disease. This study aimed to establish a nationwide collective dataset, and analyze treatment outcomes.
View Article and Find Full Text PDFJ Hosp Palliat Care
December 2024
Department of Family Medicine, Dongguk University Ilsan Hospital, Goyang-si and Department of Medicine, College of Medicine, Dongguk University, Seoul, Korea.
Advance care planning (ACP) in palliative care is essential for patient autonomy and quality of dying. This review explores ACP practices in South Korea, Japan, and Taiwan, highlighting how legislation and cultural values shape those practices. In these three sectors, which are influenced by Confucian values, family involvement plays a significant role in decision-making.
View Article and Find Full Text PDFJ Gastrointest Surg
December 2024
Kyungpook National University Chilgok Hospital School of Medicine, Kyungpook National University, Daegu, Korea.
Background: Rectal cancer surgery remains a significant technical challenge. Development and implementation of new technology offers hope for more accurate and precise surgery. To evaluate if single port robotic technology (SPR) helps achieve this goal we established an international SP robotic registry.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
December 2024
Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:
Purpose: Given the aggressive nature and poor prognosis of triple-negative breast cancer (TNBC), adjuvant capecitabine has been the standard therapy for residual disease after preoperative systemic therapy (PST). However, the optimal sequence of postoperative radiation therapy (RT) and capecitabine remains unclear. This study evaluated the efficacy and safety of concurrent RT and capecitabine (RT+CAP) versus sequential RT followed by capecitabine (RT→CAP) in patients with residual TNBC after PST.
View Article and Find Full Text PDFJ Thorac Oncol
December 2024
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea. Electronic address:
Introduction: Guideline-discordant low-dose computed tomography (LDCT) screening may cause lung cancer (LC) overdiagnosis, but its extent and consequences are unclear. This study aimed to investigate the prevalence of self-initiated, non-reimbursed LDCT screening in a predominantly non-smoking population and its impact on LC epidemiology and healthcare utilization.
Methods: This nationwide cohort study analyzed data from Korea's National Health Information Database (NHID) and eleven academic hospital screening centers (1999-2022).
BMJ Open
December 2024
Department of Obstetrics and Gynecology, Samsung Medical Center, Seoul, Korea (the Republic of).
Introduction: The use of hydroxychloroquine (HCQ) during pregnancies complicated by systemic lupus erythematosus or refractory antiphospholipid antibody syndrome has demonstrated a significant ability to prevent pre-eclampsia (PE). As such, the potential for the administration of HCQ to prevent PE in other high-risk pregnancies is an important clinical research agenda among maternal and fetal medicine specialists. Mechanistically, the anti-inflammatory and immunomodulatory effects of HCQ can offer vascular protection and inhibit the placental dysfunction-associated thrombotic changes underlying the pathophysiology of PE, fetal growth restriction (FGR) and fetal death in utero (FDIU).
View Article and Find Full Text PDFWorld Allergy Organ J
December 2024
Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Background: Limited understanding exists regarding the progression trajectory of severe eosinophilic asthma (SEA) patients on type 2 biologics therapies.
Objective: We aim to explore distinct longitudinal phenotypes of these patients based on crucial asthma biomarkers.
Methods: We enrolled 101 adult patients with SEA.
Allergy Asthma Immunol Res
November 2024
Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Purpose: Despite the emerging biologics, biomarkers and treatment options for asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) are still limited, requiring further research.
Methods: We enrolled 378 ACO patients from a multicenter real-world asthma cohort in Korea and compared the clinical characteristics, lung function, and exacerbation between type 2 (T2)-high and T2-low groups. We used the following comparisons: 1) low vs.
Hip Pelvis
December 2024
Division of Rheumatology, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea.
Br J Surg
November 2024
School of Medicine, Ulster University, Derry, UK.
Diabetes Metab J
November 2024
Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Probiotics Antimicrob Proteins
November 2024
Department of Immunology, School of Medicine, Kyungpook National University, 680 Gukchaebosang-Ro, Jung-Gu, Daegu, 41944, Republic of Korea.
Neurogastroenterol Motil
January 2025
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
BMC Gastroenterol
November 2024
Department of Internal Medicine, Inje University College of Medicine, Inje University Haeundae Paik Hospital, Busan, Republic of Korea.
ERJ Open Res
November 2024
Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Background: Recently, cough reflex hypersensitivity has been proposed as a common underlying feature of chronic cough in adults. However, symptoms and clinical characteristics of cough hypersensitivity have not been studied amongst phenotypes of chronic cough. This study aimed to compare symptom features, such as cough triggers and associated throat sensations, of cough hypersensitivity in patients with asthmatic chronic cough and those with refractory chronic cough (RCC).
View Article and Find Full Text PDFStem Cell Res Ther
November 2024
School of Life Science and Biotechnology, BK21 FOUR KNU Creative BioResearch Group, Kyungpook National University, Daegu, 41566, Korea.
Allergy
December 2024
Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, South Korea.
Cardiology
November 2024
School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Introduction: The diagnosis of myocardial infarction (MI) needs to be swift and accurate, but definitively diagnosing it based on the first test encountered in clinical practice, the electrocardiogram (ECG), is not an easy task. The purpose of the study was to develop a deep learning (DL) algorithm using multitask learning method to differentiate patients experiencing MI from those without coronary artery disease using image-based ECG data.
Methods: A DL model was developed based on 11,227 ECG images.
Oncologist
November 2024
Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
In Vivo
October 2024
Department of Pathology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea
Discov Oncol
October 2024
Department of Physics and Chemistry, DGIST, Daegu, Republic of Korea.
The challenges associated with liquid biopsy of colorectal cancer (CRC) are closely linked to the substantial variations observed in gene expression profiles among patients. This variability complicates the selection of an ideal biomarker for accurate diagnosis. In this report, we propose that employing a combination of miRNAs offers a better change for enhancing the accuracy of CRC diagnosis compared to solely relying on single miRNAs.
View Article and Find Full Text PDFDiabetol Int
October 2024
Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, 807 Hoguk-Ro, Buk-Gu, Daegu, 41404 Republic of Korea.
Neurol Sci
October 2024
Department of Neurology, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Hoguk-ro 807, Buk-gu, Daegu, Republic of Korea.
JSLS
October 2024
Department of Surgery, Daegu Catholic University School of Medicine, Daegu, Korea. (Drs. Park and Kim).
Background And Objectives: Complete preservation of the splenic vessels is ideal during laparoscopic spleen-preserving distal pancreatectomy (LSPDP). However, this remains challenging and time-consuming because the vessels are often deeply embedded in the pancreatic parenchyma. Herein, we introduce our inferior-medial approach to laparoscopic splenic vessel-preserving distal pancreatectomy (lap-SVPDP) and evaluate its safety and feasibility.
View Article and Find Full Text PDF