2,441 results match your criteria: "Kyoto Institute of Technology.[Affiliation]"

Relationship between Tilt Sensation Ability and Lower Limb Injuries in Junior Athletes.

Int J Environ Res Public Health

July 2024

Faculty of Arts and Sciences, Kyoto Institute of Technology, Hashikami-cho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.

The purpose of this study was to devise a tilt sensation measurement method to evaluate ankle proprioception and to examine its reliability. It was also used to determine the relationship among tilt sensation abilities, physical development, and lower limb injuries in junior athletes. In this study, a step platform created tilt angles.

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Sesamin Exerts an Antioxidative Effect by Activating the Nrf2 Transcription Factor in the Glial Cells of the Central Nervous System in Larvae.

Antioxidants (Basel)

June 2024

Biomedical Research Center, Graduate School of Science and Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo, Kyoto 606-0962, Japan.

Article Synopsis
  • Sesame seeds contain sesamin, which activates the Nrf2 transcription factor, promoting health benefits such as lifespan extension and reduced oxidative stress.
  • Research showed that in larvae fed sesamin, Nrf2 activation occurred in the central nervous system (CNS), gut, and salivary glands, particularly in glial cells rather than neurons.
  • Although sesamin increased the expression of certain antioxidative genes, it did not enhance resistance to the pesticide imidacloprid, suggesting its potential health effects might also apply to human tissues.
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() is one of the most common sources of infection in humans and animals. The emergence of which acquires resistance to various antibiotics has made treatment difficult. Bacteriophages can be considered promising agents to expand the options for the treatment of antibiotic-resistant bacteria.

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Effect of rapid cooling on residual stress and surface fracture toughness of dental zirconia.

J Mech Behav Biomed Mater

September 2024

Ceramic Physics Laboratory, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto, Japan; Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University, Osaka, 573-1010, Japan.

Short-time sintering of dental zirconia not only improves manufacturing efficiency of zirconia prosthetics, but also enables an attractive situation in which prosthetic treatment can be completed within a single visit. Although many studies have clarified the effects of heating rate and dwell time on the properties of dental zirconia during short-time sintering, there are only a few studies on rapid cooling. In this study, we investigated the effect of cooling rate on dental zirconia.

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Article Synopsis
  • - A new group of inhibitors designed to target the mitotic motor protein CENP-E was developed using a chemical method that combines 1,3-diketones with different hydrazines under gentle conditions.
  • - The research successfully explored how the structure of the pyrazole photoswitch affects the activity of these CENP-E inhibitors in lab tests (in vitro) and living cells.
  • - This study enhances our understanding of how these inhibitors work and their potential applications in biological systems.
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As a novel synthetic method for unsymmetrical macrocycles, we herein developed a post-synthetic modification of calix[4]arenes by insertion of a terminal alkyne into an inert C(methylene)-C(aryl) bond of the macrocyclic framework. In this transformation, C-iridated calix[4]arenes, readily synthesized through C-H bond activation of the parent calix[4]arene, undergoes C(methylene)-C(aryl) bond cleavage followed by insertion of an alkyne to provide a ring-expanded calix[4]arene complex. Removal of the iridium metal from the resulting complex was readily accomplished by a simple treatment with an acid.

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Neuroevolution is a promising approach for designing artificial neural networks using an evolutionary algorithm. Unlike recent trending methods that rely on gradient-based algorithms, neuroevolution can simultaneously evolve the topology and weights of neural networks. In neuroevolution with topological evolution, handling crossover is challenging because of the competing conventions problem.

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Construction of multilayered small intestine-like tissue by reproducing interstitial flow.

Cell Stem Cell

September 2024

Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan; AMED-CREST, Japan Agency for Medical Research and Development (AMED), Tokyo 100-0004, Japan. Electronic address:

Recent advances have made modeling human small intestines in vitro possible, but it remains a challenge to recapitulate fully their structural and functional characteristics. We suspected interstitial flow within the intestine, powered by circulating blood plasma during embryonic organogenesis, to be a vital factor. We aimed to construct an in vivo-like multilayered small intestinal tissue by incorporating interstitial flow into the system and, in turn, developed the micro-small intestine system by differentiating definitive endoderm and mesoderm cells from human pluripotent stem cells simultaneously on a microfluidic device capable of replicating interstitial flow.

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Perilipins are evolutionarily conserved from insects to mammals. Drosophila lipid storage droplet-1 (LSD-1) is a lipid storage droplet membrane surface-binding protein family member and a counterpart to mammalian perilipin 1 and is known to play a role in lipolysis. However, the function of LSD-1 during specific tissue development remains under investigation.

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The bacterial pathogen, lipopolysaccharide (LPS), elicits microglial response and induces cytokine secretion that subsequently activates astrocytes. Recent findings have indicated that LPS-induced activation of postnatal glial cells has led to alterations in synapse formation in hippocampal and cortical neurons, thereby resulting in a prolonged increased risk for seizure or depression. Nevertheless, its mechanisms remain to be fully elucidated.

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We prove that the class of crossed product C*-algebras associated with the action of the multiplicative group of a number field on its ring of finite adeles is rigid in the following explicit sense: Given any *-isomorphism between two such C*-algebras, we construct an isomorphism between the underlying number fields. As an application, we prove an analogue of the Neukirch-Uchida theorem using topological full groups, which gives a new class of discrete groups associated with number fields whose abstract isomorphism class completely characterises the number field.

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Structure and dynamics of amphiphilic patchy cubes in a nanoslit under shear.

J Chem Phys

July 2024

Faculty of Mechanical Engineering, Kyoto Institute of Technology, Goshokaido-cho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.

Patchy nanocubes are intriguing materials with simple shapes and space-filling and multidirectional bonding properties. Previous studies have revealed various mesoscopic structures such as colloidal crystals in the solid regime and rod-like or fractal-like aggregates in the liquid regime of the phase diagram. Recent studies have also shown that mesoscopic structural properties, such as an average cluster size M and orientational order, in amphiphilic nanocube suspensions are associated with macroscopic viscosity changes, mainly owing to differences in cluster shape among patch arrangements.

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Open and Closed Cage Silsesquioxane Dimers.

Chempluschem

November 2024

Faculty of Molecular Chemistry and Engineering, Kyoto Institute of Technology, Goshokaido-cho, Matsugasaki, Sakyo-ku, Kyoto, 606-8585, Japan.

Polyhedral oligomeric silsesquioxane (POSS) is an organic-inorganic hybrid molecule with two structural variations, closed- and open-cage configurations, referred to as completely condensed POSS (CC-POSS) and corner-opened POSS (CO-POSS), respectively. In this study, we synthesized 12 dimers by combining CC- and CO-POSS variants decorated with isobutyl or phenyl substituents to explore their structure-property relationships. The choice of substituents, both at the cage vertices and open sites, significantly affected the thermal and optical properties of the materials.

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Flow-injection spin-trapping electron paramagnetic resonance (FI-EPR) methods that involve the use of 5,5-dimethyl-pyrroline--oxide (DMPO) as a spin-trapping reagent have been developed for the kinetic study of the O radical scavenging reactions occurring in the presence of various plant-derived and synthetic phenolic antioxidants (Aox), such as flavonoid, pyrogallol, catechol, hydroquinone, resorcinol, and phenol derivatives in aqueous media (pH 7.4 at 25 °C). The systematically estimated second-order rate constants () of these phenolic compounds span a wide range (from 4.

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Ratiometric sandwich-type assays for RNAs with a point mutation using benzo[a]pyrene-modified probes.

Chem Commun (Camb)

July 2024

Faculty of Molecular Chemistry and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto, 606-8585, Japan.

Benzo[a]pyrene-modified oligonucleotides were developed for the detection of RNAs with a point mutation. The probes produced two distinct fluorescence signals in response to single nucleotide differences in the RNA sequences, allowing for discrimination between the matched and single base mismatched RNA sequences in colorimetric and ratiometric manners.

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Effects of fan cooling with an air-perfused rucksack on physiological and perceptual strains in young men while running in uncompensable hot environment.

J Sports Med Phys Fitness

October 2024

Graduate School of Health and Sport Sciences, Laboratory for Exercise Physiology and Biomechanics, Chukyo University, Toyota, Japan.

Background: Cooling devices reduce thermal strain during pre-, between-, and postexercise. However, their efficacy during moderate/intensity runs in hot conditions with airflow equivalent to the running speed remains unclear. This study assessed physiological and perceptual responses to neck and upper back fan-cooling through an air-perfused rucksack under such conditions.

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With the growing demand for postsilicon electronics, the purification of single-walled carbon nanotubes (SWCNTs) in terms of their chirality, which defines their atomic and electronic structure, is becoming increasingly important. Herein, we demonstrate the selective extraction of high-quality semiconducting SWCNTs using alkyl cellulose as a dispersant in organic solvents. We investigated the separation factors of dispersant structures, such as the degree of substitution (DS) and molecular weight, and clarified the appropriate dispersant structures, such as moderately substituted hexyl cellulose, for selective semiconducting SWCNT extraction.

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In this paper, we propose a Transformer-based encoder architecture integrated with an unsupervised denoising method to learn meaningful and sparse representations of vibration signals without the need for data transformation or pre-trained data. Existing Transformer models often require transformed data or extensive computational resources, limiting their practical adoption. We propose a simple yet competitive modification of the Transformer model, integrating a trainable noise reduction method specifically tailored for failure mode classification using vibration data directly in the time domain without converting them into other domains or images.

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Solar water evaporation offers a promising solution to address global water scarcity, utilizing renewable energy for purification and desalination. Transition-metal selenite hydrates (specifically nickel and cobalt) have shown potential as solar absorbers with high evaporation rates of 1.83 and 2.

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In our previous study, two oleanane-type pentacyclic triterpenoids (oleanolic acid and maslinic acid) were reported to affect the -glycosylation and intracellular trafficking of intercellular adhesion molecule-1 (ICAM-1). The present study was aimed at investigating the structure-activity relationship of 13 oleanane-type natural triterpenoids with respect to the nuclear factor κB (NF-κB) signaling pathway and the expression, intracellular trafficking, and -glycosylation of the ICAM-1 protein in human lung adenocarcinoma A549 cells. Hederagenin, echinocystic acid, erythrodiol, and maslinic acid, which all possess two hydroxyl groups, decreased the viability of A549 cells.

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Test of the negative feedback hypothesis of colony size sensing in social insects.

Biol Lett

June 2024

Department of Subtropical Agro-Environmental Sciences, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan.

Social insects can sense colony size-even without visual information in a dark environment. How they achieve this is yet largely unknown. We empirically tested a hypothesis on the proximate mechanism using ant colonies.

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In semiconductor manufacturing, the sublimation drying process is crucial but poorly understood-particularly regarding the solidification of agents such as cyclohexanol on Si substrates. This knowledge gap results in inconsistent film properties and risks such as structural collapse. To address this critical gap in knowledge, the present study focused on an in-depth examination of the nucleation behavior exhibited by cyclohexanol during its cooling and solidification on Si substrates.

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The transcription factor nuclear factor κB (NF-κB) is activated by proinflammatory cytokines, such as tumor necrosis factor α (TNF-α) and Toll-like receptor (TLR) ligands. Screening of NPDepo chemical libraries identified porphyrin derivatives as anti-inflammatory compounds that strongly inhibited the up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression induced by TNF-α, interleukin-1α, the TLR3 ligand, and TLR4 ligand in human umbilical vein endothelial cells. In the present study, the mechanisms of action of porphyrin derivatives were further elucidated using human lung adenocarcinoma A549 cells.

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