73 results match your criteria: "Kyorin University School of Health Sciences.[Affiliation]"
Physiother Theory Pract
November 2023
Department of Kaifukuki-suppot, Hatsudai Rehabilitation Hospital, Shibuya, Japan.
Objective: This study investigated the characteristics of physical activity according to sit-to-stand, standing, and stand-to-sit abilities in subacute stroke with walking difficulty.
Methods: In this study, 29 participants with subacute stroke and walking difficulty were enrolled and classified into two groups: participants who successfully completed three items (i.e.
J Am Coll Surg
September 2021
Department of Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Background: Despite the major advances in analgesic techniques, pain relief in coughing after abdominal surgery remains challenging. Cough-related pain causes postoperative respiratory complications by impairing sputum clearance; nevertheless, an effective technique to abolish it is not yet available. We devised the bilateral flank compression (BFC) maneuver, in which the flanks are compressed medially using both hands.
View Article and Find Full Text PDFInt J Hematol
September 2021
Kawasaki Medical School Hospital, Kurashiki, Japan.
Although it is known that red blood cell (RBC) parameters and platelet count depend on ethnicity and sex, their reference intervals in healthy Asian populations are limited. The aim of this study was to establish reference intervals for RBC parameters and platelet count for healthy adults in Japan. A total of 750 healthy adults (447 women and 303 men; median age 40 years (18-67 years) at seven Japanese centers who participated in regular medical checkups entered this study.
View Article and Find Full Text PDFTop Stroke Rehabil
January 2020
Department of Physical Therapy, Kyorin University School of Health Sciences, Mitaka, Japan.
: Little is known about the benefits of daytime physical activity on gait ability in subacute stroke.: We investigated association between daytime physical activity at hospital admission and improvement of gait independence 1 month later in subacute stroke.: Thirty-four participants with subacute stroke who could not walk independently were assessed.
View Article and Find Full Text PDFPsychoneuroendocrinology
November 2019
Department of Health Science, Kitasato University School of Allied Health Sciences, Japan.
Cortisol is known to affect visuospatial memory through its major binding site in the brain, the hippocampus. The synchronization of neural activity between the hippocampus, prefrontal cortex (PFC), and visual cortex is presumed to be essential for the formation of visuospatial memory because of their visuospatial learning-dependent neuroplasticity. However, it remains unclear how hippocampal connectivity with the PFC and visual cortex is involved in the relationship between cortisol and visuospatial memory in humans.
View Article and Find Full Text PDFPhys Ther Res
May 2019
Department of Physical Therapy, Kyorin University School of Health Sciences.
Objective: Gait ability may be related to the level of intensity-based physical activity in people who have experienced a stroke; however, this relationship has not been explored in previous studies. This study aimed to investigate the characteristics of intensity-based physical activity according to gait ability and to explore the factors related to different intensity physical activity.
Method: Eighty hospitalized participants with subacute stroke were assigned to three groups based on their gait ability: group 1 (n = 28) could walk independently with a maximal gait speed (MGS) of more than 0.
J Affect Disord
October 2018
Department of Health Sciences, Kitasato University School of Allied Health Sciences, 1-15-1, Kitasato, Sagamihara, Kanagawa 252-0373, Japan.
Top Stroke Rehabil
May 2018
c Department of Physical Therapy , Kyorin University School of Health Sciences, Mitaka , Japan.
Background Activity monitors are known to provide quantitative evaluation of physical activity in people with stroke. However, little evidence is available on the test-retest reliability and suitable measuring conditions for evaluating physical activity with an activity monitor in people with subacute stroke at a hospital setting. Objectives To evaluate reliability of physical activity measurement using an activity monitor in different measuring conditions in hospitalized people with subacute stroke according to gait ability.
View Article and Find Full Text PDFSci Rep
August 2017
Department of Health Sciences, Kitasato University School of Allied Health Sciences, Kanagawa, Japan.
The amygdala plays a critical role in emotion. Its functional coupling with the hippocampus and ventromedial prefrontal cortex extending to a portion of the anterior cingulate cortex (ACC) is implicated in anxiogenesis and hypothalamic-pituitary-adrenal (HPA) system regulation. However, it remains unclear how amygdala-centred functional connectivity (FC) affects anxiety and cortisol concentrations in everyday life.
View Article and Find Full Text PDFSci Rep
October 2016
Department of Health Sciences, Kitasato University School of Allied Health Sciences, Kanagawa, Japan.
J Hum Genet
September 2007
Department of Public Health, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
Pulmonary function is a crucial factor associated with longevity. Mitochondrial DNA 5178 cytosine/adenine (Mt5178 C/A) polymorphism is reported to be associated with longevity in the Japanese population. We have previously reported that Mt5178 C/A polymorphism is widely associated with physiological and biochemical status.
View Article and Find Full Text PDFAnal Biochem
December 2006
Department of Clinical Biochemistry, Kyorin University School of Health Sciences, Miyashita, Hachioji, Tokyo 192-8508, Japan.
A new enzymatic assay for specifically measuring allantoin concentration in serum has been developed. The currently used methods for allantoin analysis are time consuming and nonspecific or depend on the use of expensive equipment. In our method, allantoin is converted to allantoate by the action of allantoinase (EC 3.
View Article and Find Full Text PDFJ Hum Genet
November 2006
Department of Public Health, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, 181-8611, Japan.
NADH dehydrogenase subunit-2 237 leucine/methionine (ND2-237 Leu/Met) polymorphism is reportedly associated with longevity in the Japanese population. The ND2-237Met genotype may confer resistance to cardiovascular and cerebrovascular atherogenic diseases. Hyperuricemia is one of the risk factors for cardiovascular disease.
View Article and Find Full Text PDFCancer Sci
April 2006
Department of Environmental and Life Sciences, Kyorin University School of Health Sciences, 876 Miyashita-cho, Hachhioji, Tokyo 192-8508, Japan.
To elucidate the relationship between dsx and mab-3 related transcription factor 1 (Dmrt-1) and differentiation, alteration in mRNA levels during differentiation of NEC8 human embryonic carcinoma cells was investigated. After stimulation with 50 nM phorbol 12-myristate 13-acetate (PMA), the cells differentiated into cells with mesenchymal characteristics and upregulated Dmrt-1 mRNA, possibly through the protein kinase C/mitogen-activated protein kinase/activated protein-1 signaling pathway. Conversely, knockdown of Dmrt-1 by small interfering RNA resulted in cell morphology that was different from that after PMA treatment.
View Article and Find Full Text PDFAppl Environ Microbiol
January 2004
Department of Microbiology, Kyorin University School of Health Sciences, Tokyo 192-8508, Japan.
DNA fragments were amplified by PCR from all tested strains of Aeromonas hydrophila, A. caviae, and A. sobria with primers designed based on sequence alignment of all lipase, phospholipase C, and phospholipase A1 genes and the cytotonic enterotoxin gene, all of which have been reported to have the consensus region of the putative lipase substrate-binding domain.
View Article and Find Full Text PDFBiochem Biophys Res Commun
January 2004
Department of Medical Genetics, Kyorin University School of Health Sciences, 146 Miyashita-cho, Hachioji, Tokyo 192-8508, Japan.
Human Single-minded 1 (SIM1) and SIM2 genes were found as homologs of Drosophila sim gene which plays a key role in the midline cell lineage of the central nervous system. SIM proteins belong to a family of transcription factors, called bHLH/PAS. Here we examined the intracellular localization of SIM proteins using the expression constructs of whole SIM2 or SIM1 protein fused with enhanced green fluorescent protein (EGFP).
View Article and Find Full Text PDFClin Chim Acta
October 2003
Laboratory of Biochemistry, Kyorin University School of Health Sciences, 476 Miyashita-machi, Hachioji, Tokyo 192-8508, Japan.
Background: An association of variations in the calpain-10 gene (CAPN10) with type 2 diabetes was originally reported in Mexican Americans. However, some studies in other racial groups were contradictory.
Methods: We studied the influence of genotypes and haplotype combinations (haplogenotypes) of CAPN10 on the metabolic traits in 286 Japanese subjects who visited a General Health Check-up Center.
Cytopathology
April 2003
Department of Cytology, Kyorin University School of Health Sciences, Tokyo, Japan.
In Japan, there are some problems with fine needle aspiration (FNA) cytology of the breast, such as insufficient smeared cells, air-drying artefact and excessive erythrocytes. Liquid-based cytology has been found to solve these problems. Equipment for such preparations has been developed, but can be expensive to purchase and operate.
View Article and Find Full Text PDFBiochem Biophys Res Commun
February 2003
Depatment of Clinical Pathology, Kyorin University School of Health Sciences, 476 Miyashita-cho, Hachioji, Tokyo 192-8508, Japan.
To clarify the therapeutic effects of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin (6R-BH(4)) on the abnormal behaviors induced by neonatal 5,7-dihydroxytryptamine (5,7-DHT, 100 microg; i.c.v.
View Article and Find Full Text PDFFEMS Microbiol Lett
September 2002
Department of Clinical Biochemistry, Kyorin University School of Health Sciences, 476 Miyashita, Hachioji, Tokyo 192-8508, Japan.
In Saccharomyces cerevisiae, there are two isoenzymes of fumarate reductase (FRDS1 and FRDS2), encoded by the FRDS and OSM1 genes, respectively. Simultaneous disruption of these two genes results in a growth defect of the yeast under anaerobic conditions, while disruption of the OSM1 gene causes slow growth. However, the metabolic role of these isoenzymes has been unclear until now.
View Article and Find Full Text PDFInt Clin Psychopharmacol
June 2002
Department of Mental Health, Kyorin University School of Health Sciences, Hachioji, Tokyo, Japan.
Milnacipran is one of the first modern antidepressant drugs to be introduced into Japan, and the first dual-action antidepressant. Placebo-controlled clinical trials with this drug have demonstrated similar efficacy and superior tolerability to imipramine and mianserin. The good safety profile of the drug has been confirmed from open-label phase IV studies.
View Article and Find Full Text PDFAnal Biochem
August 2002
Department of Clinical Biochemistry, Kyorin University School of Health Sciences, Miyashita, Hachioji, Tokyo, Japan.
Analysis of serum proteins by native polyacrylamide gel electrophoresis is difficult because albumin is abundant in serum and interferes with the resolution of other proteins, especially alpha-antitrypsin which has mobility that is very similar to that of albumin. We present here a method in which serum proteins are separated by polyacrylamide gel electrophoresis using stacking gels containing Blue Sepharose CL-6B, which has a high affinity for albumin, lipoproteins, kinases, and pyridine-nucleotide-dependent oxidoreductases. During electrophoresis, proteins that bind to Blue Sepharose CL-6B stay in the stacking gel and do not migrate into the separating gel.
View Article and Find Full Text PDFJ Chromatogr A
June 2002
Department of Pathological Biochemistry, Kyorin University School of Health Sciences, Hachioji, Tokyo, Japan.
One-step capillary isoelectric focusing (cIEF), which uses reduced but non-zero electroosmosis flow to mobilize the focused proteins, was applied to the analysis of proteins in cerebrospinal fluid (CSF) and serum of patients with various neurological disorders. Under the conditions employed, pathological changes in the CSF proteins were clearly detected on the electropherograms within 25 min, although the serum proteins did not vary significantly between samples. The present one-step cIEF system seems to be useful in routine laboratory examinations of a large number of CSF samples as an aid in neurological diagnosis.
View Article and Find Full Text PDFDiagn Cytopathol
July 2002
Department of Cytology, Kyorin University School of Health Sciences, Hachioji, Tokyo, Japan.
The presence of papillary cell clusters is taken as a serious indication in the diagnosis of well-differentiated endometrial adenocarcinoma in Japan. However, papillary-like clusters have been observed in both normal and benign samples. Therefore, overdiagnosis may occur in the observation of cytopreparations.
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