38 results match your criteria: "Kyono ART Clinic[Affiliation]"

Deliveries of babies with normal health derived from oocytes with smooth endoplasmic reticulum clusters.

J Assist Reprod Genet

November 2014

Kyono ART Clinic, Mitsui-Seimei, Sendai Honcho Bl, 3F, 1-1-1 Honcho, Aoba-ku, Sendai, Miyagi, 980-0014, Japan.

Purpose: To examine the impact on development of derived embryos from smooth endoplasmic reticulum clusters (SERC) in human metaphase II (MII) oocytes.

Methods: Retrospective analysis at Kyono ART Clinic. Comparison of embryological development, pregnancy, live birth and fetal malformation between oocytes with SERC (the SERC(+) group) and those without (the SERC(-) group) in 2,158 patients (3,758 cycles) after ICSI.

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Purpose: The purpose of this study was to evaluate the effect of transportation at prolonged low temperatures on the survival of pre-antral follicles.

Methods: Ovarian tissue was removed from six women with gender identity disorder. Tissues were stored in an icebox at 4 °C for 6 or 18 h prior to vitrification.

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Purpose: To report a live birth from vitrified-warmed oocytes for a Philadelphia chromosome-positive acute lymphoid leukemia (Ph-ALL) patient.

Methods: A 20-year-old single woman with Ph-ALL requested oocyte cryopreservation at a private fertility clinic using assisted reproduction technology (ART). In cases of leukemia, there is a very short time before chemotherapy, follwed shortly by total body irradiation (TBI), and although she had already received the chemotherapy, ten oocytes were vitrified and stored for 59 months before warming.

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There is a long-held credo, as illustrated in Langman's Medical Embryology (11th ed., Sadler, 2010), that dichorionic diamniotic (DD) twins develop after embryo splitting in the early stages of embryonic development. However, from our clinical experiences of the examination of data from single-embryo transfers in 16 fertility clinics in Japan and from various reports, the majority of occurrences of DD twins have been found in the blastocyst stages.

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Purpose: To report the world's first case of live monozygotic dichorionic diamniotic (DD) twins after a single vitrified-warmed blastocyst transfer in a cycle during which hormone supplements were given.

Methods And Results: The patient was a 39-year-old woman with tubal factor infertility. Six oocytes were retrieved and three blastocysts were vitrified after insemination with her husband's sperm.

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Objective: To describe the delivery of a healthy female infant after intracytoplasmic sperm injection (ICSI) using pentoxifylline-activated sperm from a patient with Kartagener's syndrome.

Design: Case report.

Setting: Private assisted reproductive technology clinic in Japan.

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A birth of twins-one boy and one girl-from a single embryo transfer and a possible natural pregnancy.

J Assist Reprod Genet

April 2010

Kyono ART Clinic, Mitsui-Seimei, Sendai Honcho Bld., 3F, 1-1-1, Honcho, Aobaku, Sendai, Miyagi, 980-0014, Japan,

Purpose: To describe a rare case of a birth of dizygotic twins with different-sex infants from a single embryo transfer.

Methods And Results: A patient, who had her right ovary and tube removed, and her husband were treated with ICSI and a single embryo transfer. When a single fresh embryo was transferred on day 4, following oocyte retrieval using GnRH agonist-long protocol, two gestational sacs were recognized at 8 weeks of gestation.

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Ovarian cryopreservation and autotransplantation could be of potential value for preservation of fertility in the patients with various malignancies. Ovarian tissue should be cryopreserved actively for fertility preservation, but stored tissue should be autotransplanted with much caution until reliable methods are established to detect minimal residual disease in grafts in precise and reproducible manners.

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Article Synopsis
  • * The patient had non-obstructive azoospermia; after warming oocytes, all six survived, leading to a 100% fertilization rate and production of five blastocysts.
  • * Two blastocysts were transferred in the successful attempt, resulting in the delivery of a healthy baby boy.
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Objective: To present the effectiveness of diagnostic heterologous intracytoplasmic sperm injection (ICSI), mouse oocyte activation test (MOAT), and ICSI combined with assisted oocyte activation (AOA) in a globozoospermic patient.

Design: A case report.

Setting: A private IVF center, Japan.

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Objective: To examine the outcomes of intracytoplasmic sperm injection (ICSI) with testicular sperm retrieved from men with spinal cord injury.

Design: Retrospective study.

Setting: Private hospital-based infertility research laboratory.

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Birth and follow-up of babies born following ICSI using SrCl2 oocyte activation.

Reprod Biomed Online

July 2008

Kyono ART Clinic, 3F Mitsuiseimei Sendai Honcho Building, 1-1-1 Honcho, Aobaku, Sendai 980-0014, Japan.

This report describes six successful pregnancies (five healthy children from four deliveries and two miscarriages) with SrC1(2) oocyte activation using spermatozoa from nine patients with repeated fertilization failure. Oocytes were artificially activated by SrC1(2) 30 min after intracytoplasmic sperm injection (ICSI). Oocytes were placed in 10 mmol/l of SrC1(2) medium for 1 h, rinsed several times, and then cultured in Universal IVF medium.

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Objective: To compare the fertilization and pregnancy rates using fresh testicular sperm between nonobstructive azoospermic (NOA) patients and obstructive azoospermic (OA) patients.

Design: We evaluated sperm quality of testicular sperm retrieved by microdissection testicular sperm extraction (MD-TESE) in NOA patients and compared the fertilization rate and pregnancy rate via intracytoplasmic sperm injection (ICSI) between NOA and OA patients.

Setting: Private hospital-based infertility research laboratory.

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