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Impact of MASLD on Portal Vein Thrombosis Following Hepatectomy for Liver Cancer.
Cancers (Basel)
November 2024
Department of Surgery, Kyoaikai Tobata Kyoritsu Hospital, Kitakyushu 804-0093, Fukuoka, Japan.
Article Synopsis
- The prevalence of non-alcoholic fatty liver disease (NAFLD), now referred to as metabolic dysfunction-associated steatotic liver disease (MASLD), is rising, especially among patients undergoing liver surgery (hepatectomy) due to liver cancer.
- A study of 106 hepatectomy patients found that those with MASLD had a significantly higher incidence of post-hepatectomy portal vein thrombosis (PH-PVT) compared to those without steatosis.
- MASLD and its variant associated with moderate alcohol consumption (MetALD) were identified as major risk factors for PH-PVT, suggesting that metabolic dysfunction plays a critical role in thrombosis risk post-surgery.