Structural insights into 1,4-bis-(neopent-yloxy)pillar[5]arene and the pyridine host-guest system.

The crystal structure of 1,4-bis-(neopent-yloxy)pillar[5]arene, CHNO (, featuring two encapsulated pyridine mol-ecules, reveals significant host-guest inter-actions. Inter-estingly, the pyridine guests are positioned near the neopent-yloxy substituents instead of the electron-rich aromatic core of the pillar[5]arene. This spatial arrangement suggests a preference for the pyridine mol-ecules to engage with the aliphatic regions of the host.

An international survey on the knowledge, attitudes and clinical patterns of use of medical cannabis for cancer care: The TASMAN study.

Background: Medical cannabis (MC) has gained traction in oncology for managing cancer-related symptoms, but its integration faces challenges due to limited evidence, inconsistent guidelines, and varied legal frameworks.

Methods: The TASMAN study aimed to assess the knowledge, attitudes, and practices of oncologists and palliative care providers globally regarding MC use in cancer care. A survey of healthcare providers from diverse regions and income levels was conducted.

A twin of Polydora hoplura (Annelida: Spionidae) from the Arabian (Persian) Gulf, with review of primers used for barcoding of Spionidae.

The spionid polychaete Polydora hoplura Claparède, 1868 has been widely recorded boring in shells of abalone, oysters, clams, barnacle tests and sponges in temperate and subtropical waters. Molecular studies have suggested conspecificity of individuals collected worldwide but showed high genetic variability of the species with the highest diversity of haplotypes in the South African population. We have compared the morphology and genetic data of shell-boring worms from Kuwait, which were previously assigned to P.

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort.

Schizophrenia presents significant diagnostic and treatment challenges, particularly in distinguishing between treatment-resistant (TRS) and non-treatment-resistant schizophrenia (NTRS). This cross-sectional study analyzed routine laboratory parameters as potential biomarkers to differentiate TRS, NTRS, and healthy individuals within a Qatari cohort. The study included 31 TRS and 38 NTRS patients diagnosed with schizophrenia, alongside 30 control subjects from the Qatar Biobank.

The Meaning of Being a 'Good Nurse' in the ICU During the COVID-19 Pandemic.

Intensive care unit (ICU) nurses were at the forefront of patient care during the coronavirus (COVID-19) pandemic. To date, no studies have explored what it meant to be a 'good nurse' in this unique and challenging context. As such, the aim of this study was to construct the meaning of the 'good nurse' in ICUs during a pandemic.

Multisociety consensus recommendations on hepatitis delta virus infection.

Hepatitis D virus (HDV) prevalence data and country-specific HDV guidelines are not widely available in the Gulf Cooperation Council (GCC) states. We developed consensus recommendations to guide healthcare professionals, policymakers, and researchers in improving HDV management and patient health outcomes in three GCC states: Kuwait, Saudi Arabia, and the United Arab Emirates. A consensus panel comprising hepatology experts (n = 6) from the three GCC societies was formed.

Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network.

Background: Effectiveness of disease-modifying treatment (DMT) in people affected by primary progressive multiple sclerosis (PPMS) is limited. Whether specific subgroups may benefit more from DMT in a real-world setting remains unclear. Our aim was to investigate the potential effect of DMT on disability worsening among patients with PPMS stratified by different disability trajectories.

Dual scale light weight cross attention transformer for skin lesion classification.

Skin cancer is rapidly growing globally. In the past decade, an automated diagnosis system has been developed using image processing and machine learning. The machine learning methods require hand-crafted features, which may affect performance.

Revolutionizing Fingerprint Detection: Ce Doped SiO-ZrO:Sr Nanocomposites with Enhanced Luminescence and Selectivity.

Even though fingerprints remain one of the most reliable methods of identification, they are often lost during the recovery process. Accurate fingerprint recognition depends on the contrast between the ridges and substrate. On tough surfaces, such as glossy, colorful, and patterned materials, the contrast is harder to establish.

The relationship between the secondary implant stability quotient and oxidized implant-related factors: A retrospective study.

Objective: The present retrospective study aimed to determine the relationship between the secondary implant stability quotient and different parameters related to an oxidized implant.

Methods: A total of 135 patients (305 oxidized implants) were included. Implant-related factors (length, diameter, surgical and loading protocols, grafting, insertion torque, and primary stability) were used for comparisons and linear regression analyses, using secondary ISQ as the dependent variable.

Adipocyte Angptl8 deletion improves glucose and energy metabolism and obesity associated inflammation in mice.

Angiopoietin-like protein 8 (Angptl8), expressed in the liver and adipocytes, forms a complex with Angptl3 or Angptl4, which regulates lipoprotein lipase and triglyceride metabolism. However, the precise functions of adipocyte Angptl8 remain elusive. Here we report that adipocyte-specific inducible Angptl8-knockout (AT-A8-KO) male mice on normal diet showed minor phenotypic changes, but after a high-fat high fructose (HFHF) diet, exhibited decreased body weight gain and glycemia, elevated rectal temperature and early dark phase energy expenditure compared to the Cre controls.

Isolated sphenoid sinus fungal mucoceles: A rare entity with a high propensity for causing neurological complications.

Background: Isolated sphenoid sinus fungal mucoceles are extremely rare and potentially associated with visual disturbances, cranial nerve (CN) deficits, or pituitary dysfunction. Their initial symptoms are often absent or nonspecific, and routine examination offers little information, resulting in diagnostic and therapeutic delays. A high index of suspicion and a thorough understanding of their clinical presentation, neuroradiological features, microbiological implications, and complication profile are crucial for early diagnosis and prompt management.

Toward Efficient Hydrogen Generation Using Nickel-Molybdenum Catalyst and Its Environmental Sustainability.

In this study, a catalyst with Ni-Mo combination was synthesized using the electric heating/reductive tempering method. Nickel (II) nitrate hexahydrate and ammonium molybdate were combined in a ratio of 1.1 in this approach.

Credibility-based knowledge graph embedding for identifying social brand advocates.

Brand advocates, characterized by their enthusiasm for promoting a brand without incentives, play a crucial role in driving positive word-of-mouth (WOM) and influencing potential customers. However, there is a notable lack of intelligent systems capable of accurately identifying online advocates based on their social interactions with brands. Knowledge Graphs (KGs) offer structured and factual representations of human knowledge, providing a potential solution to gain holistic insights into customer preferences and interactions with a brand.

Achieving simultaneous removal of carbon and nitrogen by an integrated process of anaerobic membrane bioreactor and flow-through biofilm reactor.

In this study, a combined system consisting of an anaerobic membrane bioreactor (AnMBR) and flow-through biofilm reactor/CANON (FTBR/CANON) was developed to simultaneously remove carbon and nitrogen from synthetic livestock wastewater. The average removal efficiencies of total nitrogen (TN) were 64.2 and 76.

Clinical Considerations for Crown Lengthening: A Comprehensive Review.

Clinical crown lengthening is a surgical procedure that involves the manipulation of gingival tissue, designed to expose sound tooth structure for restorative purposes by apically repositioning the gingival tissue, with or without the removal of alveolar bone. Crown lengthening may be subdivided as functional or esthetic, according to the purpose of treatment. Functional crown lengthening pertains to the exposure of subgingival caries, fractures, or to avoid invading the biologic width.

Psychological antecedents of vaccine inequity: keys to improve the rates of vaccination.

Background: The World Health Organization (WHO) stresses the importance of worldwide vaccine coverage of coronavirus-19 (COVID-19) vaccination. This study fills a critical gap in the literature by providing empirical evidence on the factors influencing COVID-19 vaccine hesitancy and inequity in the Middle East and North Africa (MENA) region. This study investigated the determinants of psychological antecedents and other factors behind COVID-19 vaccination and their role in vaccine coverage in MENA.

Evaluation of modified fire hawk optimizer for new modification in double diode solar cell model.

The evaluation of photovoltaic (PV) model parameters has gained importance considering emerging new energy power systems. Because weather patterns are unpredictable, variations in PV output power are nonlinear and periodic. It is impractical to rely on a time series because traditional power forecast techniques are based on linearity.