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Nucleotide sequence analysis of a DNA region involved in capsular polysaccharide biosynthesis reveals the molecular basis of the nontypeability of two Actinobacillus pleuropneumoniae isolates.

J Vet Diagn Invest

November 2016

The National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan (Ito, Kusumoto)Fukuoka Chuo Livestock Hygiene Center, Higashi-ku, Fukuoka, Japan (Ogawa, Fukamizu, Morinaga).

The aim of our study was to reveal the molecular basis of the serologic nontypeability of 2 Actinobacillus pleuropneumoniae field isolates. Nine field strains of A. pleuropneumoniae, the causative agent of porcine pleuropneumonia, were isolated from pigs raised on the same farm and sent to our diagnostic laboratory for serotyping.

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