8 results match your criteria: "Kurume Coloproctology Center[Affiliation]"
Crohn's Disease-Associated Anorectal Cancer Has a Poor Prognosis With High Local Recurrence: A Subanalysis of the Nationwide Japanese Study.
Am J Gastroenterol
September 2023
Tokyo Medical and Dental University, Tokyo, Japan.
Article Synopsis
- Colorectal cancer (CRC) presents a significant risk for patients with Crohn's disease (CD), and this study aimed to investigate the prognosis and characteristics of CD-related CRC (CD-CRC) compared to sporadic CRC using a large database of cases.
- The analysis included 233 CD-CRC patients and 129,783 sporadic CRC patients, revealing that CD-CRC patients were typically younger, more likely to have rectal cancer, multiple tumors, and a distinct type of cancer called mucinous adenocarcinoma, all resulting in lower survival rates.
- The findings showed a lower five-year overall survival rate for CD-CRC (53.99% vs. 71.17% for sporadic CRC
Effect of Biologics on the Risk of Advanced-Stage Inflammatory Bowel Disease-Associated Intestinal Cancer: A Nationwide Study.
Am J Gastroenterol
July 2023
Department of Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Article Synopsis
- - The study aimed to assess how biologic drugs influence the risk of advanced-stage intestinal cancer in patients with inflammatory bowel disease (IBD) using a comprehensive nationwide dataset.
- - Analyzing records from 1,042 patients with Crohn's disease (CD) and ulcerative colitis (UC), it was found that biologics significantly reduced the risk of advanced-stage cancer in UC patients, but not in CD patients.
- - The findings suggest different cancer progression mechanisms between UC and CD, highlighting the need for further research in understanding these differences.
Lower effectiveness of intravenous steroid treatment for moderate-to-severe ulcerative colitis in hospitalised patients with older onset: a multicentre cohort study.
Aliment Pharmacol Ther
June 2022
Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Background: The increasing incidence of older-onset ulcerative colitis (UC), which has a higher risk of surgery, is a global health issue. However, data regarding intravenous steroid treatment, one of the important treatment options to avoid surgery, for older-onset UC is lacking.
Aims: To evaluate the association between onset age and effectiveness of intravenous steroids in UC.
Changes in the rate of and trends in colectomy for ulcerative colitis during the era of biologics and calcineurin inhibitors based on a Japanese nationwide cohort study.
Surg Today
December 2019
Department of Surgery, Fukuoka University Chikushi Hospital, Chikusino, Japan.
Purpose: We evaluated the recent incidence of surgery and the changing surgery trends for ulcerative colitis (UC) in Japan due to the increasing use of anti-tumor necrosis factor (TNF) agents.
Methods: A questionnaire survey was performed to assess the number of surgeries, surgical indications, surgical timing, and immunosuppressive treatments before surgery between 2007 and 2017.
Results: A total of 3801 surgical cases were reported over 11 years.
Leukocytapheresis for the treatment of active pouchitis: a pilot study.
J Gastroenterol
November 2008
Kurume Coloproctology Center, Kurume, Japan.
Background: Pouchitis is a major long-term complication of ileal pouch-anal anastomosis for ulcerative colitis. The aim of this study is to investigate the efficacy of leukocytapheresis for the treatment of active pouchitis.
Methods: Eight patients with active pouchitis received leukocytapheresis weekly for 5 weeks in an open-label treatment protocol together with baseline therapy.
Perineal hernia in women : assessment with evacuation fluoroscopic cystocolpoproctography.
Kurume Med J
August 2008
Kurume Coloproctology Center, Kurume, Japan.
The aim of this study is to assess the usefulness of fluoroscopic cystocolpoproctography in the treatment of female pelvic organ prolapse. The presence or absence of rectocele, enterocele, sigmoidocele, and the cystocele on cystocolpoproctography was retrospectively analyzed in 46 consecutive patients. A rectocele was detected in 4.
View Article and Find Full Text PDFGraciloplasty for internal and external sphincteric resection of lower rectal cancer.
Kurume Med J
February 2005
Kurume Coloproctology Center, Kurume 839-0865, Japan.
Anal sphincteric resection for rectal cancer is most commonly followed by colostomy in the lower abdominal wall, which enforces quite a poor quality of life due to a permanent stoma. For surgeons treating lower rectal cancer, the goal is to achieve defecation via the anus without placing a stoma. Internal sphincteric resection, partial external sphincteric resection and coloanal anastomosis have been reported for the treatment of lower rectal cancer with avoiding a colostoma.
View Article and Find Full Text PDFClipless hand-assisted laparoscopic total colectomy using Ligasure Atlas.
Kurume Med J
December 2004
Kurume Coloproctology Center, Kurume 839-0861, Japan.
Hand-assisted laparoscopic total colectomy for ulcerative colitis has allowed less invasive operations in acute severe colitis and poor risk, and has not yet been widely applied for the reason of prolong the operating time in comparison with open surgery. We present the advantages of the use of the LigaSure Atlas vessel sealing for vascular control during laparoscopic surgery. A retrospective study was conducted to compare 15 patients who underwent hand-assisted laparoscopic total colectomy using an ultrasonic coagulator from January 1988 to September 2002 (US group) with 18 patients who were operated using LigaSure Atlas (LS group) from October 2002 to December 2003.
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