1 results match your criteria: "Kunming Kingmed Institute for Clinical Laboratory Co. Ltd[Affiliation]"
Systematic analysis of the adverse effects of commonly used clinical tetracycline drugs based on the FAERS database.
Expert Opin Drug Saf
August 2024
Kunming Kingmed Institute for Clinical Laboratory Co. Ltd, Kunming, Yunnan province, China.
Article Synopsis
- Tetracyclines are widely used antibacterial drugs, but their adverse effects (AEs) had not been systematically analyzed until this study, which utilized the FDA's FAERS database from 2004 to 2023.
- The research identified 15,020 cases and calculated signal values for various AEs linked to different tetracycline drugs, with notable findings such as doxycycline causing gastrointestinal issues and minocycline linked to skin pigmentation changes.
- The study highlighted previously unreported AEs like ototoxicity, along with psychiatric effects from doxycycline and concerns related to tumors from minocycline, suggesting that awareness of these risks should be increased among healthcare providers and patients.