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Exp Ther Med
October 2012
Department of Neurology, The First People's Hospital of Yunnan, Kunhua Affiliated Hospital of Kunming Medical University, Kunming 650032;
Depression is a highly debilitating and widely distributed illness in the general population. Geranylgeranylacetone (GGA), a non-toxic anti-ulcer drug, has been reported to have protective effects in the central nervous system. The aim of this study was to determine the antidepressant effect of GGA in a chronic mild stress (CMS) model of depression.
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