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Pro-healing effect of Cinnamomum zeylanicum bark.

Phytother Res

September 2003

Department of Pharmacology, Krupanidhi College of Pharmacy Sarjapur Road, Koramangala, Bangalore 560034, India.

The ethanol extract of the bark of Cinnamomum zeylanicum was evaluated for wound healing activity in Wistar rats. The extract was administered by the oral route at a dose of 250 mg/kg and 500 mg/kg body weight (1/8 and 1/4 of LD(50), respectively) for all the wound models selected, excision, incision and dead space wounds. The extract significantly enhanced the wound breaking strength in the case of incision wound, the rate of wound contraction and the period of epithelization in the case of excision wound.

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