8 results match your criteria: "Kozawa Eye Hospital and Diabetes Center[Affiliation]"
Aflibercept Biosimilar MYL-1701P vs Reference Aflibercept in Diabetic Macular Edema: The INSIGHT Randomized Clinical Trial.
JAMA Ophthalmol
October 2024
Clinical Development & Medical Affairs Department, Biocon Biologics Ltd, Bangalore, Karnataka, India.
Article Synopsis
- Biosimilars like MYL-1701P, a version of aflibercept, offer potentially cheaper options for treating diabetic macular edema (DME), but their efficacy and safety compared to the original have not been fully studied.
- A randomized double-masked trial across multiple countries involved 355 participants with DME to compare MYL-1701P and aflibercept, focusing on vision improvement and side effects over a year.
- Results showed similar improvements in visual acuity between the two treatments after 8 weeks, with MYL-1701P achieving an adjusted mean difference of just 0.04 letters from aflibercept, indicating comparable effectiveness.
Variability of urinary albumin to creatinine ratio and eGFR are independently associated with eGFR slope in Japanese with type 2 diabetes: a three-year, single-center, retrospective cohort study.
BMC Nephrol
August 2024
Department of Internal Medicine, Kozawa Eye Hospital and Diabetes Center, 246-6 Yoshizawa-cho, Mito, Ibaraki, 310-0845, Japan.
Article Synopsis
- The study aimed to investigate how the urinary albumin to creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) fluctuate with the seasons and how these fluctuations affect the eGFR over three years in individuals with type 2 diabetes (T2D).
- Researchers analyzed data from 1,135 T2D patients in Japan and found that UACR varied with seasons, peaking in winter, while eGFR remained stable throughout the year.
- Results indicated that both the variability in UACR and eGFR significantly influenced the eGFR decline over the three years, especially in patients not changing their medication during the study.
Introduction: The aim of this study was to evaluate the refractive error in patients undergoing combined phacovitrectomy with and without gas tamponade.
Methods: This was a retrospective chart review including patients undergoing phacoemulsification alone (Group 1), combined phacovitrectomy for epiretinal membrane (Group 2), and combined phacovitrectomy with gas tamponade for rhegmatogenous retinal detachment (RRD) (Group 3). Axial length and keratometry were measured using an optical biometric system (Argos, Alcon Laboratories.
Background: This study evaluated the safety and effectiveness of combining intravitreal brolucizumab injection with sub-tenon's capsule triamcinolone acetonide injection (STTA) during the loading phase for polypoidal choroidal vasculopathy (PCV).
Methods: In this retrospective observational study, untreated patients with PCV receiving intravitreal brolucizumab injections with STTA during loading at Saitama Medical University Hospital's Eye Center from May 2021 to June 2022 were analyzed. Complete regression rates of polypoidal lesions were assessed using indocyanine green angiography 12 weeks post-treatment initiation.
Analysis of Facial Features of Patients With Sagging Eye Syndrome and Intermittent Exotropia Compared to Controls.
Am J Ophthalmol
February 2023
Kozawa Eye Hospital and Diabetes Center (K.K., T.G., S.T., E.I.), Mito, Ibaraki, Japan.
Article Synopsis
- - The study aimed to compare the facial features of patients with sagging eye syndrome (SES) and other eye conditions to see if facial features could help diagnose SES.
- - Researchers analyzed photographs of patients over 60 years old, evaluating specific eye characteristics across three groups: SES, intermittent exotropia (IXT), and a control group, while excluding patients with certain criteria.
- - Results showed that patients with SES had notably more sunken upper eyelids compared to the other groups, and those with IXT had more baggy lower eyelids, indicating different manifestations of age-related eye changes.
Objective classification of zonular weakness based on lens movement at the start of capsulorhexis.
PLoS One
September 2017
Department of Ophthalmology, Tokyo Dental College Suidobashi Hospital, Tokyo, Japan.
Purpose: To quantify zonular weakness based on lens movement at the start of continuous curvilinear capsulorhexis (CCC) and establish a classification system for it.
Setting: Kozawa Eye Hospital and Diabetes Center, Mito, Japan.
Design: Retrospective interventional case series.
Modified capsule expander implantation to reposition and fixate the capsular bag in eyes with subluxated cataractous lenses and phacodonesis: intermediate-term results.
J Cataract Refract Surg
March 2015
From the Department of Ophthalmology (Asano, Yaguchi, Nishimura, Soda), School of Medicine, University of Showa, Fujigaoka Rehabilitation Hospital, Yokohama, and the Kozawa Eye Hospital and Diabetes Center (Kozawa), Mito, Japan.
Purpose: To report the intermediate-term results of capsule stabilization for scleral fixation with implantation of the Yaguchi hook, a modified capsule expander stabilization hook.
Setting: Department of Ophthalmology, School of Medicine, University of Showa, Fujigaoka Rehabilitation Hospital, Yokohama, Japan.
Design: Retrospective case series.
Comparison of the outcomes of limbal-based trabeculectomy with and without anchor sutures.
Ophthalmic Surg Lasers Imaging
March 2010
Kozawa Eye Hospital and Diabetes Center, 246-6, Yoshizawa-cho, Mito City, Ibaraki Pref. 310-0845 Japan.
Background And Objective: To retrospectively evaluate the efficacy and safety of limbal-based trabeculectomy with anchor sutures compared to standard limbal-based trabeculectomy. Limbal-based trabeculectomy was performed with a new technique using anchor sutures, which involved tying the conjunctiva to the sclera at a deep fornix incision to prevent bleb localization induced by slippage of the conjunctival suture scar toward the scleral flap.
Patients And Methods: In this retrospective, comparative, interventional case series, 45 eyes that underwent limbal-based trabeculectomy with anchor sutures and 27 eyes that underwent standard limbal-based trabeculectomy were analyzed (primary surgery).