12 results match your criteria: "Koseikai Hospital[Affiliation]"

Case: We report a case of coccygeal dislocation complicated by defecatory dysfunction and discuss its treatment and mechanisms. A 58-year-old man was presented with coccygeal pain and defecatory dysfunction after sustaining an injury from a 1-m fall. Following diagnosis, a combined approach involving surgical treatment and physiotherapy was adopted, resulting in early symptom improvement and favorable long-term outcomes.

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Association between the gut microbiome and organic acid profiles in a Japanese population with HIV infection.

J Infect Chemother

January 2024

Department of Microbiology and Infectious Diseases, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8521, Japan.

Introduction: An increased incidence of metabolic syndrome has been observed in human immunodeficiency virus (HIV)-infected individuals. In contrast, gut dysbiosis is involved in various pathogeneses, including vascular endothelial disorders. Organic acids, including short-chain fatty acids (SCFAs), are essential for maintaining gut homeostasis.

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We report two cases of chronic portal vein occlusion with jejunal varices successfully treated using percutaneous intervention with a combined transhepatic and transsplenic approach. Case 1 was a 60-year-old man with uncontrolled jejunal variceal bleeding, and case 2 was a 79-year-old man with anastomotic jejunal variceal bleeding and cholangitis. Single access via the transhepatic or transsplenic route failed to allow catheter advancement through the occlusion.

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Aims: Relationship between baseline eGFR and the rate of decline in eGFR was investigated in diabetic kidney disease.

Materials And Methods: Patients with type 2 diabetes with microalbuminuria (MI) ( = 124) or macroalbuminuria (MA) ( = 81) received team-based medical care to prevent the development of diabetic kidney disease. The decline in eGFR over 4 years, divided into the first year and subsequent 3 years, was estimated by linear-mixed modeling.

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Acute-type lateral ridge defects (25 mm × 6 mm × 5 mm) were bilaterally created in the mandibles of four dogs (two defects per animal). The defects were reconstructed with particulate autologous bone and covered with a microperforated titanium membrane (Ti-honeycomb membrane, TiHM) or an existing conventional titanium mesh as control. The samples were dissected after 16 weeks postoperatively and processed for radiographic, histologic, and histomorphometric analyses.

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Article Synopsis
  • - The N-DOCC-F-C-1701 trial aims to test the effectiveness and safety of a combination treatment (CPT-11+S-1+Ramucirumab) for metastatic colorectal cancer, expecting better results than a different combination that includes Bevacizumab.
  • - The trial will involve 38 patients and focuses on progression-free survival as its primary goal, while also looking at other factors like overall response and survival rates, side effects, and quality of life.
  • - If successful, this research could lead to the new treatment becoming a standard option for patients with metastatic colorectal cancer who have already undergone oxaliplatin-based therapies.
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A 28-year-old man with a history of coil embolization of multiple pulmonary arteriovenous malformations presented with hemoptysis 11 years after initial embolization. A cavity lesion in the left upper lobe, which was accompanied by deformed coils and ground-glass opacity, was considered responsible for hemoptysis. Embolization of the bronchial artery was performed.

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Background: Evaluation of brain β-amyloid by positron emission tomography (PET) imaging can assist in the diagnosis of Alzheimer disease (AD) and other dementias.

Methods: Open-label, nonrandomized, multicenter, phase 3 study to validate the (18)F-labeled β-amyloid tracer florbetaben by comparing in vivo PET imaging with post-mortem histopathology.

Results: Brain images and tissue from 74 deceased subjects (of 216 trial participants) were analyzed.

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Background And Objective: Aspirin, clopidogrel, cilostazol, and statins are thought to reduce the risk of cerebral infarction in patients with intracranial arterial stenosis. We present a case of multiple intracranial arterial stenoses in which increased cerebral blood flow (CBF) was demonstrated after long-term medical therapy.

Case Presentation: A 68-year-old man with a history of cerebral infarction showed complete occlusion of the left internal carotid artery with severe stenoses in the A1 segment of the left anterior cerebral artery (ACA) and the left posterior communicating artery resulting in poor visualization of the left middle cerebral artery (MCA) on magnetic resonance angiography (MRA).

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Successful repair of left ventricular (LV) pseudoaneurysm after mitral valve replacement (MVR) is uncommon, with delayed onset showing particularly high mortality. We report a case of delayed LV pseudoaneurysm onset after MVR reoperation. The patient had unique clinical symptoms, including coronary ischemia due to compression of the left main coronary artery by the aneurysm.

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A 70-year-old woman with Marfan syndrome had undergone Y-graft replacement for abdominal aortic aneurysm at the age of 61. She recently underwent axillo-bifemoral bypass to treat ischemia of the lower extremities caused by acute aortic dissection. The patient was admitted for surgical treatment to treat a remaining dissecting descending aortic aneurysm.

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