3 results match your criteria: "KortexMed Institute of Medical Education[Affiliation]"
Supplementation with red palm oil increases β-carotene and vitamin A blood levels in patients with cystic fibrosis.
Mediators Inflamm
January 2016
Division of Pediatric Pulmonology & Allergy and Cystic Fibrosis Centre, Department of Pediatrics III, Children's Hospital, University of Heidelberg, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany ; Translational Lung Research Centre Heidelberg (TLRC), Member of the German Centre for Lung Research (DZL), Im Neuenheimer Feld 350, 69120 Heidelberg, Germany ; Department of Translational Pulmonology, University of Heidelberg, Im Neuenheimer Feld 350, 69120 Heidelberg, Germany.
Patients with cystic fibrosis (CF) show decreased plasma concentrations of antioxidants due to malabsorption of lipid soluble vitamins and consumption by chronic pulmonary inflammation. β-Carotene is a major source of retinol and therefore is of particular significance in CF. The aim of this study was to investigate the effect of daily intake of red palm oil (RPO) containing high amounts of β-carotene on the antioxidant levels in CF patients.
View Article and Find Full Text PDFMetabolism of 4-hydroxy-2-nonenal in human polymorphonuclear leukocytes.
Arch Biochem Biophys
November 2010
Department of Physiotherapy and Gerontology, KortexMed Institute of Medical Education, Bad Harzburg, Germany.
Intracellular metabolism of 4-hydroxy-2-nonenal (HNE), a major product and mediator of oxidative stress and inflammation, is analyzed in resting and fMLP-stimulated human polymorphonuclear leukocytes (PMNL), where this compound is generated during activation of the respiratory burst. HNE consumption rate in PMNL is very low, if compared to other cell types (rat hepatocytes, rabbit fibroblasts), where HNE metabolism is always an important part of secondary antioxidative defense mechanisms. More than 98% of HNE metabolites are identified.
View Article and Find Full Text PDFOxysterols are increased in plasma of end-stage renal disease patients.
Kidney Blood Press Res
May 2006
Research Institute of Physiotherapy and Gerontology, KortexMed Institute of Medical Education, Bad Harzburg, Germany.
Background/aims: Oxidative stress occurs in chronic renal failure patients undergoing hemodialysis (HD). The objective of our study was to measure oxidation products of cholesterols, so-called oxysterols, in the serum of HD patients in comparison to healthy control persons.
Methods: In 42 HD patients, plasma oxysterols were measured before and after HD.