Exoskeleton Robot Training in Two Patients with an Electrical Burn and Septic Arthritis: A Case Report.

Septic arthritis (SA) are rare in patients with burns, but delayed treatment can result in irreversible joint destruction. Early diagnosis and immediate treatment are necessary to prevent joint destruction. Robot training in patients with musculoskeletal diseases and burns, can improve joint range of motion (ROM), muscle strength, and lower extremity function.

Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course.

Background: Earlier identification of high coronary artery disease (CAD) risk individuals may enable more effective prevention strategies. However, existing 10-year risk frameworks are ineffective at earlier identification. We sought to understand how the variable importance of genomic and clinical factors across life stages may significantly improve lifelong CAD event prediction.

Effects of the narrative elaboration technique and open-ended rapport on accuracy of children's recall according to age.

Introduction: This study explored the impacts of the narrative elaboration technique (NET) and open-ended rapport building on younger ( = 30, ages 5-6) and older ( = 30, ages 7-8) children's free recall and suggestibility.

Methods: Children were randomly assigned to either a NET condition or an open-ended rapport condition after engaging in a photo-taking play session with an experimenter. Then, a novel interviewer asked them about the play session.

Aspirin modulates inflammatory biomarkers in patients with subcortical silent brain infarcts.

Introduction: This study aimed to identify differences in the levels of inflammation-related biomarkers between patients with subcortical silent brain infarcts (SBIs) and healthy controls. We also evaluated the effect of aspirin on the subcortical SBI inflammatory processes.

Methods: Consecutive patients diagnosed with subcortical SBIs without a history of acute stroke were included.

Suppression of dopamine receptor 2 inhibits the formation of human prostate cancer PC‑3‑derived cancer stem cell‑like cells through AMPK inhibition.

Cancer stem cells (CSCs) contribute to the resistance of intractable prostate cancer, and dopamine receptor (DR)D2 antagonists exhibit anticancer activity against prostate cancer and CSCs. Human prostate cancer PC-3 cells were used to generate CSC-like cells, serving as a surrogate system to identify the specific DR subtype the inhibition of which significantly affects prostate-derived CSCs. Additionally, the present study aimed to determine the downstream signaling molecules of this DR subtype that exert more profound effects compared with other DR subtypes.

Prediction of delirium occurrence using machine learning in acute stroke patients in intensive care unit.

Introduction: Delirium, frequently experienced by ischemic stroke patients, is one of the most common neuropsychiatric syndromes reported in the Intensive Care Unit (ICU). Stroke patients with delirium have a high mortality rate and lengthy hospitalization. For these reasons, early diagnosis of delirium in the ICU is critical for better patient prognosis.

single nucleotide polymorphism reduces dabigatran acylglucuronide formation in humans.

Background: Dabigatran etexilate (DABE), a prodrug of dabigatran (DAB), is a direct thrombin inhibitor used to prevent ischemic stroke and thromboembolism during atrial fibrillation. The effect of genetic polymorphisms on its metabolism, particularly , has not been extensively explored in humans. This study aimed to investigate the effects of , , and polymorphisms on the pharmacokinetics of DAB and its acylglucuronide metabolites in healthy subjects.

Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells.

Background: Polydatin (3,4',5-trihydroxy-3-β-d-glucopyranoside, PD) is known for its antioxidant and anti-inflammatory properties. Oxaliplatin (OXA)-based chemotherapy is the first-line treatment for metastatic and recurrent colorectal cancer (CRC). However, the lack of selectivity for normal cells often results in side effects.

Hospital utilization and telemedicine preferences in patients with late-stage Parkinson's disease and caregivers.

Background: There remains a significant gap in systematic research on healthcare utilization behaviors and the influencing factors for patients with Parkinson's disease (PD), particularly those in late stages.

Methods: PD patients in late stage (Hoehn and Yahr (HY) stages 4 and 5) and their caregivers from Seoul National University Hospital Movement Disorders Clinic participated. A total of 103 respondents completed a questionnaire covering medical utilization behaviors, perceptions of face-to-face and telemedicine consultations, and additional medical service needs.

Traditional herbal medicine for Guillain-Barré syndrome: A systematic review and meta-analysis.

Background: Guillain-Barré syndrome (GBS) is a rapid-onset disease caused by the immune system damaging the peripheral nervous system. Since most standardized treatments for GBS focus on acute phase treatment, there are limitations to the rehabilitation and management of general conditions. In East Asian countries, herbal medicine has been used to treat GBS and aid rehabilitation.

Depressive symptoms and quality of life among women experiencing infertility: The moderating effect of perceived social support.

Background: Infertility constitutes a leading reproductive health problem with profound psychosocial outcomes, including elevated depressive symptoms that compromise quality of life (QoL). While the literature has suggested social support as a protective psychological mechanism, its role in depressive symptoms and QoL among women with infertility remains underexplored. This study aimed to examine the moderating effect of perceived social support on the relationship between depressive symptoms and QoL among South Korean women experiencing infertility.

Advancing vaccine technology through the manipulation of pathogenic and commensal bacteria.

Advancements in vaccine technology are increasingly focused on leveraging the unique properties of both pathogenic and commensal bacteria. This revolutionary approach harnesses the diverse immune modulatory mechanisms and bacterial biology inherent in different bacterial species enhancing vaccine efficacy and safety. Pathogenic bacteria, known for their ability to induce robust immune responses, are being studied for their potential to be engineered into safe, attenuated vectors that can target specific diseases with high precision.

OsWRKY26 negatively regulates bacterial blight resistance by suppressing expression.

Plants are susceptible to infection by various pathogens with high epidemic potential. pv () causes bacterial blight in rice, one of the most significant diseases in both temperate and tropical regions. In this study, we report the identification and characterization of , a sucrose-inducible transcription factor, that plays a role in the plant defense responses following infection.

Optimizing adsorption and photocatalysis for tetracycline and sulfamethoxazole removal: the role of Ag and NH in Bi-MOF derivatives.

This study focuses on the synthesis, characterization, and evaluation of the photocatalytic efficiency of bismuth-based metal-organic frameworks (Bi-MOFs) and their derivatives, specifically Ag/Bi-MOF and NH /Ag/Bi-MOF, in the degradation of tetracycline (TC) and sulfamethoxazole (SMX) under visible light irradiation. Bi-MOFs are promising photocatalysts due to their large surface area, tunable porosity, and unique electronic properties that are favorable for visible light absorption. In this study, Bi-MOFs were synthesized using a solvothermal method, with the incorporation of silver (Ag) and ammonium (NH ) ions to enhance their photocatalytic performance.

Automated classification of stress and relaxation responses in major depressive disorder, panic disorder, and healthy participants via heart rate variability.

Background: Stress is a significant risk factor for psychiatric disorders such as major depressive disorder (MDD) and panic disorder (PD). This highlights the need for advanced stress-monitoring technologies to improve treatment. Stress affects the autonomic nervous system, which can be evaluated via heart rate variability (HRV).

The Prevalence of Tear Patterns and Their Effects on Tendon Healing After Arthroscopic Surgery in Patients With Full-Thickness Rotator Cuff Tears.

Background: To achieve successful anatomic rotator cuff repair with minimal tension, both the tear pattern and tear size should be considered. However, little information is available concerning the frequency of tear patterns and their effects on tendon healing.

Purpose: To evaluate the distribution of tear patterns in full-thickness rotator cuff tears and whether these patterns affect tendon healing after arthroscopic repair.

The Trend in Age-Adjusted Incidence of Head and Neck Cancer in South Korea over the Past 20 Years.

Objectives: We aimed to calculate the age-adjusted incidence rate of head and neck cancer (HNC) in South Korea from 1999 to 2020 and investigate the incidence trend of HNC excluding the effect of population aging.

Methods: Data were obtained from the Cancer Registration Statistics Program. All 12 types of HNCs were analyzed.

Apparent diffusion coefficient values in differentiating benign and malignant thoracic masses in children and young adults.

Background: In children and young adults, tumors in the chest and thoracic wall exhibit a wide variety of types, making it challenging to differentiate between benign and malignant cases before invasive histopathological examination.

Purpose: To evaluate the utility of apparent diffusion coefficient (ADC) for discriminating malignant thoracic masses in children and young adults.

Material And Methods: This retrospective study included chest magnetic resonance imaging (MRI) scans in patients aged <30 years.

Exploring the Proteomic Landscape and Immunomodulatory Functions of Derived Extracellular Vesicles.

Extracellular vesicles (EVs) have garnered attention in research for their potential as biochemical transporters and immune modulators, crucial for regulating the host immune system. The present study was conducted to isolate and characterize EVs from Gram negative bacteria (EVs) and investigate their proteomic profile and immune responses. Isolation of EVs was carried out using ultracentrifugation method.

sp. nov., Isolated from the Marine Sponge, , and Reclassification of as comb. nov.

A Gram-stain-negative, facultative anaerobic rods, designated as strain 219JJ12-13, was isolated from a marine sponge, , in Jeju-do, Republic of Korea. The cells displayed catalase and oxidase activity and were non-motile. Strain 219JJ12-13 grew at 10-37°C (optimum, 25-30°C), pH 6.

Protective Potential of Strains and Their Mixture on Inflammatory Bowel Disease via Regulating Gut Microbiota in Mice.

The aim of this study is to investigate the protective potential of IM57, IR51, and IR62 strains, isolated from infant feces, and their mixture against inflammatory bowel disease (IBD). The strains exhibited robust antioxidant activities and anti-inflammatory properties in RAW 264.7 cells.

Wurmb Extract Recovered Compromised Immune Status Induced by Forced Swimming in a Mouse Model.

Wurmb is known to contain large amounts of polyphenols and flavonoids with antioxidative and anti-inflammatory effects. However, the biological and physiological functions of have not been scientifically investigated. Thus, we investigated the immunomodulatory effect of hot water extract (YSK-N) in mice using an immune compromised model established by forced swimming (FS).