2 results match your criteria: "KonkukUniversity[Affiliation]"
Current paradigms in employing self-assembled structures: Drug delivery implications with improved therapeutic potential.
Colloids Surf B Biointerfaces
February 2024
Biotransformation and Biomaterials Lab, Department of Biological Engineering, College of Engineering, KonkukUniversity, Hwayang-dong Gwangjin-gu, Seoul 05029, South Korea. Electronic address:
Article Synopsis
- - Recent advancements in drug delivery systems have highlighted the use of micelles made from amphiphilic block copolymers, which present benefits like biodegradability, biocompatibility, and sustained drug release, but require further enhancements for efficiency and stability.
- - Researchers are working on optimizing the performance of these micelles by addressing challenges like toxicity and stability, while employing various strategies such as protecting hydrophobic cores and prolonging blood circulation through polyethylene oxide coatings.
- - This article discusses the potential of nanoscale self-assembled structures for drug delivery and emphasizes the need for rigorous research and structural modifications to improve micelle efficacy in clinical applications.
Preventive effects of COX-2 inhibitor, celecoxib on renal tubular injury induced by shock wave lithotriptor.
Urol Res
August 2010
Department of Urology, College of Medicine, KonkukUniversity, Chungju, Korea.
Our study was designed to investigate the protective effect of the COX-2 inhibitor, celecoxib, on renal tubules against shock wave lithotripsy (SWL). Sprague-Dawley rats were randomly divided into three groups: sham, control, and COX-2 groups. The control group was administrated normal saline.
View Article and Find Full Text PDF