79 results match your criteria: "Kofu National Hospital[Affiliation]"

It has been hypothesized that the biopsychosocial stress associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, in combination with the immunological effects of SARS-CoV-2 and pancreatic β-cell dysfunction, may contribute to the onset of type 1 diabetes (T1D) in children. In this study, we documented the incidences of T1D in Yamanashi Prefecture, Japan, from 1986 to 2018, and expanded the analysis to include cases from 2019 to 2022 to evaluate the potential influence of coronavirus disease 2019 (COVID-19) on T1D incidence. The COVID-19 pandemic period was defined as 2020 to 2022.

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Aim: To compare the incidence of end-stage renal disease (ESRD) between slowly progressive type 1 diabetes and acute-onset type 1 diabetes.

Methods: This cohort study enrolled all 521 patients with childhood-onset type 1 diabetes with the year of onset from 1959 to 1996 in Hokkaido Prefecture, Japan. We calculated the ESRD incidence rate per 100,000 person-years by sex, onset year, onset age, and type 1 diabetes subtype (slowly progressive or acute-onset).

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Diagnostic challenges in imaging and immunohistopathological profiles in extraskeletal osteosarcoma.

World J Surg Oncol

November 2024

Department of Orthopaedic Surgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.

Article Synopsis
  • The article by Nie et al. discusses a rare case of extraskeletal osteosarcoma (EO) found in the sigmoid mesocolon, diagnosed through imaging and histopathology.
  • Diagnosing EO is complicated due to non-specific imaging properties and limited immunohistochemical markers, with SATB2 being a proposed but not highly specific option.
  • It's crucial to differentiate EO from other soft tissue sarcomas, like dedifferentiated liposarcoma, as some markers may overlap, complicating diagnosis.
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Myofibroblastomas are benign mesenchymal tumors that frequently occur in the groin. They show variable morphology, and the differential histopathological diagnoses are broad, including lipomatous to myxoid tumors. In addition, both pathological and imaging findings may be complex, which makes diagnosis challenging.

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  • Human pose estimation is a computer vision technique that captures body representations from images and videos, and its application in clinical photography for conditions like adolescent idiopathic scoliosis (AIS) is being explored.
  • A study with 42 AIS patients analyzed preoperative photographs to derive photographic parameters and compared these to traditional radiographic measures using statistical analysis.
  • Significant correlations were found between photographic and radiographic measurements, suggesting that pose estimation via mobile devices could enable safer screening and monitoring of AIS without exposing patients to X-ray radiation.
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IgG4-related disease is a rare fibroinflammatory disorder characterized by the infiltration of IgG4-rich plasma cells. Herein, we report a case of IgG4-related disease of the subcutaneous tissue with atypical MRI findings and difficulties in the histopathological examination using needle biopsy. Based on the clinical presentation and MRI findings, the patient was diagnosed with a benign myxoid or cystic tumor.

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Case: Traumatic pediatric Achilles ruptures are rare, and few cases have been reported among patients with a history of Achilles tenotomy. A 17-year-old boy with a history of Achilles tenotomies for congenital clubfoot as an infant presented with acute midsubstance Achilles tendon rupture of the right leg. The gastrocnemius fascia was dissected to allow for approximation of the ruptured Achilles tendon segments.

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Abnormality in re-programing of preparatory muscle activity for landing following unpredictable events in patients with anterior cruciate ligament injury.

Knee

August 2024

Department of Health Sciences, Division of Medicine, Interdisciplinary Graduate School, University of Yamanashi, 1110 Shimokato, Chuo City, Yamanashi 409-3898, Japan.

Background: Anterior cruciate ligament deficiency (ACL-D) causes dysfunction in the quadriceps femoris muscle, and this dysfunction hampers a safe return to sports. However, how the dysfunctional quadriceps femoris muscle affects instantaneous re-programming of motor command in response to unpredictable events remains unknown. This study aimed to examine the effects of ACL-D on re-programming of preparatory muscle activity during an unpredictable landing task.

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Introduction: Segond fractures, characterized by avulsion injuries at the lateral tibial condyle's anterolateral structure (ALS) attachment, often coincide with anterior cruciate ligament (ACL) injuries, potentially leading to knee instability. However, the influence of Segond fractures on knee stability after ACL reconstruction remains uncertain. Despite documented ALS reconstructions, there is a lack of consensus regarding the assessment of ALS failure and the criteria for surgical interventions.

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Article Synopsis
  • - The study investigates whether certain anatomical characteristics linked to anterior cruciate ligament (ACL) injuries are shared among family members, comparing them to patients with simple meniscus injuries.
  • - Researchers analyzed medical records of 1548 patients and ultimately included 41 patients from 20 families with ACL injuries, looking specifically at anatomical factors like posterior-inferior tibial slope and notch width in relation to control subjects.
  • - Results revealed significant differences in anatomical measurements between families with ACL injuries and controls, indicating hereditary risk factors, which could inform future ACL injury prevention strategies.
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Aim: To examine the mortality rate and causes of death in childhood-onset type 1 diabetes in Japan.

Methods: For a median 36.7 years, we followed 391 patients under the age of 15 years who developed type 1 diabetes between 1959 and 1996.

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Arthrogenic muscle inhibition (AMI) is induced by pathological knee conditions. The present study aimed to investigate the effect of tactile stimulation on reflex changes induced by simulated AMI during unpredictable landing performances. Twenty participants performed six unilateral landing tasks: 15 cm normal landing (15NL), 30 cm normal landing (30NL), surprise landing (SL), 30 cm normal landing following vibration (30NLV), SL following vibration (SLV), and SL following vibration with Kinesiology tape (SLK).

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  • An 11-year-old boy with Ehlers-Danlos syndrome experienced severe instability of his kneecap, leading to dislocations on both the inside and outside.
  • Despite an initial surgical realignment, the instability persisted and required a more extensive procedure.
  • The boy underwent successful simultaneous reconstruction of ligaments in his knee using a tendon from his leg, resulting in improved stability.
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Background: Individual variation in kidney function can be affected by both congenital and acquired factors, and kidney function in children is possibly correlated with that in their mothers. However, the mother-child correlation in kidney function remains directly unconfirmed.

Methods: We conducted a cross-sectional study of 655 healthy pairs of 7- or 8-year-old children and their mothers as an adjunct study of a nationwide epidemiological study (Japan Environment and Children's Study).

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Article Synopsis
  • Falls are common medical accidents in hospitals, with a study of 5,219 patients from April 2016 to March 2019 revealing a 2.9% fall rate, predominantly occurring bedside and often at night.* -
  • The study utilized a fall risk assessment sheet to analyze patient backgrounds and identify risk factors, finding age, previous falls, certain behaviors (like not using the nurse call button), unstable gait, and narcotic use as significant risk factors.* -
  • The overall incidence of falls in this hospital was lower than other reports, suggesting that the fall risk assessment could be beneficial in preventing falls among hospitalized patients.*
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Combined knee injuries of the anterior cruciate ligament (ACL), medial collateral ligament (MCL), and medial meniscus were called "the unhappy triad" in the past. With recent advances in diagnostic technology, combined ACL, MCL, and lateral meniscus injuries are now known to be the predominant triad. We examined and verified the treatment outcomes of the triad of combined knee injuries from both patient-based subjective evaluation and objective assessments.

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Objectives: We investigated the clinical situation of fractures that occurred in patients in the severely disabled patients' ward of our hospital. The study aimed to identify risk factors for the occurrence of long bone fractures in the extremities, which pose problems in nursing care.

Methods: We retrospectively studied fractures that occurred between April 2015 and March 2021 among a total of 126 patients in the severely disabled patients' ward of our hospital.

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  • The study aimed to understand how patients with Stage-3 locomotive syndrome (LS) improve over time after different types of surgeries for degenerative musculoskeletal diseases.
  • It involved 168 patients who underwent spinal fusion, total hip arthroplasty, or total knee arthroplasty, with evaluations at multiple time points before and after the surgeries.
  • Results showed that a significant percentage of patients improved their LS stage two years after surgery, particularly in the hip surgery group, which also performed best on a functional assessment tool.
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Background: Kawasaki disease is suspected to be triggered by previous infection. The prevention measures for coronavirus disease 2019 (COVID-19) have reportedly reduced transmission of certain infectious diseases. Under these circumstances, the prevention measures for COVID-19 may reduce the incidence of Kawasaki disease.

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Prolonged second stage of labor is a common abnormality of labor progression. Very little research exists regarding the relationship between prolonged second stage of labor and antepartum sonographic fetal head biometry parameters, especially fetal biparietal diameter (BPD). Fetal BPD assessment is essential for estimating fetal weight, and these measurements are readily available to Japanese obstetricians.

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Objectives: Patients requiring total hip arthroplasty (THA) may possibly have locomotive syndrome (LS). Therefore, we investigated changes of LS in patients undergoing THA and clarified key factors that affected LS stage.

Methods: A prospective cohort study was conducted with 88 patients undergoing THA (74 females, 14 males, mean age: 67.

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