4 results match your criteria: "Kobe University Graduate School of Medical Science[Affiliation]"

In acute pancreatitis, multiple organ failure in the early phase and infectious complications in the late phase are contributors to mortality. To analyze the mechanism of aggravation of acute pancreatitis is to investigate the mechanism of organ dysfunction and infection. As strategy to elucidate the mechanism, various animal experimental models are utilized.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on preventing hepaticojejunostomy leaks following pancreaticoduodenostomy to avoid severe complications like abscesses and sepsis.
  • Researchers analyzed clinical records of 107 patients, assessing eight perioperative risk factors such as age, serum levels, and intraoperative conditions.
  • The findings indicated that performing an anastomotic leak test significantly reduced leak occurrences, with no leaks in patients tested through a retrograde transhepatic bile drainage catheter.
View Article and Find Full Text PDF

Arginase catalyzes the hydrolysis of arginine to urea and ornithine. Urea is not only an important solute for concentrating urine but also inhibits Na-K-2Cl cotransport. To elucidate the roles of arginase in the development of salt-sensitive hypertension, we examined arginase activity and expression in the kidney and other organs of Dahl/Rapp salt-sensitive (SS) and salt-resistant (SR) rats before and after 4 weeks' administration of a 4% NaCl or control diet.

View Article and Find Full Text PDF