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Objective: The aim of this study was to investigate the utility of different screening techniques for primary aldosteronism (PA), including serum aldosterone (SA), plasma renin activity (PRA) and the SA/PRA ratio in hypertensive patients of a tertiary-care centre. Furthermore, the influence of antihypertensive medication on SA and the SA/PRA ratio were studied.

Design: Clinical records of 425 hypertensive patients who had SA and PRA measurements over a 27-month period were analysed retrospectively.

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