29 results match your criteria: "Kisen Hospital[Affiliation]"
Clin J Am Soc Nephrol
December 2024
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Phys Ther
October 2024
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Objective: Patients with chronic kidney disease reportedly have decreased muscle oxygen utilization, which most substantially decreases exercise capacity, followed by cardiac reserve. However, determinants of longitudinal changes in exercise capacity in patients on hemodialysis and the effects of long-term exercise interventions are unknown. This study was conducted to clarify these concerns.
View Article and Find Full Text PDFAdv Exp Med Biol
October 2024
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.
The high concentration of oxygenated haemoglobin (OHb) in the prefrontal cortex (PFC) during exercise improves cognitive performance. In this study, we aimed to elucidate the relationship of cognitive function with the OHb concentration difference between the left and right PFC (L-PFC and R-PFC, respectively) during sustained exercise. We enrolled 12 healthy adult males who, after a 4-min rest and warm-up, performed a 40-min exercise regime at a workload corresponding to 50% maximal oxygen consumption.
View Article and Find Full Text PDFJACC Cardiovasc Interv
July 2024
Department of Cardiovascular Pathology, CVPath Institute, Gaithersburg, Maryland, USA; School of Medicine, University of Maryland, Baltimore, Maryland, USA. Electronic address:
Background: The success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is lower and the risk for complications higher compared with other non-CTO PCI. Although interventionalists focus on intimal plaque characteristics, the coronary media is an important (especially for techniques involving antegrade dissection and re-entry) but poorly understood structure in CTO PCI.
Objectives: The aim of the present study was to investigate coronary medial wall thinning in CTO lesions and determine how this thinning might affect CTO PCI.
Nephrology (Carlton)
October 2024
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.
Aim: Protein-energy wasting (PEW) is a common syndrome in patients undergoing haemodialysis (HD) and is associated with poor prognosis. Bioelectrical impedance analysis (BIA)-derived phase angle (PA) is useful for predicting PEW, but sex and age need to be considered. We aimed to reveal sex-specific cut-off values of PA predicting PEW in HD patients aged ≥65.
View Article and Find Full Text PDFPhys Ther
July 2024
Renal Exercise and Physical Activity Network - Virtual Laboratory, Japan.
Objective: Patients on hemodialysis are highly susceptible to falls and fractures. Amplified apprehension regarding the fear of falling (FOF) constitutes a risk factor that restricts physical activity and escalates the probability of falls among the elderly population. This study aimed to elucidate the association between falls and FOF and physical activity in patients on hemodialysis.
View Article and Find Full Text PDFEur Heart J Case Rep
January 2024
Division of Cardiology, Kisen Hospital, Tokyo, Japan.
Ther Apher Dial
June 2024
Department of Endocrinology, Metabolism and Nephrology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Introduction: There is little evidence for ivabradine hydrochloride in patients undergoing hemodialysis.
Methods: In this open-label prospective interventional trial of hemodialysis patients with chronic heart failure, during 12 weeks of treatment, changes in Heart rate (HR), frequency of dialysis-related hypotension were examined, and we investigated health-related quality of life (HR-QOL) and adverse effects.
Results: 18 patients from 6 facilities were enrolled in the study.
J Ren Nutr
July 2024
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Objective: Postexercise vagal dysfunction is linked to noncardiovascular mortality in hemodialysis patients, but the mechanism is unknown. This study aimed to determine the association of cardiovagal neuropathy with systemic inflammation, protein-energy wasting, and noncardiovascular hospitalization.
Methods: This 2-center retrospective cohort study analyzed data from 280 hemodialysis patients who underwent exercise test.
Nephrology (Carlton)
April 2024
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Aim: Circulating blood volume (BV) during exercise changes depending on the intensity and duration, and post-exercise hypotension is observed after continuous exercise. We investigated the safety and efficacy of both interval and continuous IDE at anaerobic threshold (AT) levels with respect to hemodynamic stability and dialysis efficiency.
Methods: In this crossover randomized controlled trial, 16 patients on haemodialysis were subjected to three trial arms, including non-IDE, interval-IDE, and continuous-IDE arms.
Eur Heart J Case Rep
November 2023
Division of Cardiology, Kisen Hospital, Tokyo, Japan.
Geriatr Gerontol Int
November 2023
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.
Aim: Hemodialysis (HD) patients have a high prevalence of frailty. The association between frailty and exercise capacity in HD patients has not been established. This study aimed to clarify the relationships between frailty and exercise capacity in HD patients.
View Article and Find Full Text PDFPhys Ther Res
April 2023
Department of Cardiology, Itabashi Heart Clinic, Japan.
Background: The upper extremity siding cardiac implantable electrical device tends to have a limited range of motion during the perioperative period; however, the underlying reason lacks scientific evidence. This study aimed to investigate the safety of the two methods (stepwise or early) of postoperative early upper extremity rehabilitation.
Methods: We retrospectively investigated 650 consecutive patients with a new implantable pacemaker (PM), implantable cardioverter-defibrillator (ICD), cardiac resynchronization therapy (CRT), or generator exchange between March 2017 and December 2020.
Nephrol Dial Transplant
January 2024
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata-city, Niigata, Japan.
Background: In hemodialysis patients, high body mass index is associated with low mortality while abdominal obesity relates to increased mortality. We aimed to investigate the association between muscle mass, intramuscular fat and abdominal fat measured by abdominal computed tomography (CT), and mortality in this patients population.
Methods: This two-center retrospective cohort study included hemodialysis patients who underwent abdominal CT between January 2013 and December 2018.
Clin Physiol Funct Imaging
September 2023
Department of Cardiology, Itabashi Heart Clinic, Tokyo, Japan.
This study aimed to determine how behavioural restrictions due to the emergency declaration following the coronavirus disease 2019 (COVID-19) pandemic affect exercise tolerance and its outcomes in patients in Phase III cardiac rehabilitation programme. This is a multicenter retrospective cohort study. Participants in outpatient cardiac rehabilitation programmes and cardiopulmonary exercise testing before and after the emergency declarations were included.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2022
Department of Biomedical Informatics, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
The histopathological findings of the glomeruli from whole slide images (WSIs) of a renal biopsy play an important role in diagnosing and grading kidney disease. This study aimed to develop an automated computational pipeline to detect glomeruli and to segment the histopathological regions inside of the glomerulus in a WSI. In order to assess the significance of this pipeline, we conducted a multivariate regression analysis to determine whether the quantified regions were associated with the prognosis of kidney function in 46 cases of immunoglobulin A nephropathy (IgAN).
View Article and Find Full Text PDFPLoS One
November 2022
Department of Cardiac Rehabilitation, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan.
Cardiac implantable electrical devices (CIED) such as pacemakers, implantable cardioverter defibrillators, and cardiac resynchronization therapies are generally recommended for older patients and those with severe heart failure (HF). However, there is currently a lack of evidence on the relationship between frailty and readmission rates among patients with CIED. This study investigated whether preoperative frailty influenced readmission rates among patients with CIED over a one-year period following implantation.
View Article and Find Full Text PDFFront Physiol
August 2022
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.
A recent study has reported that prefrontal cortex (PFC) activity during incremental exercise may be related to exercise termination on exhaustion. However, few studies have focused on motor-related areas during incremental exercise. This study investigated changes in the oxygenation of the PFC and motor-related areas using near-infrared spectroscopy during incremental exercise.
View Article and Find Full Text PDFEur J Appl Physiol
October 2022
Division of Cardiology, Kisen Hospital, Tokyo, Japan.
Purpose: Exercise prescription based on a population-specific physiological response can help ensure safe and effective physical interventions. However, as a facile approach for exercise prescription in hemodialysis population that is based on their exercise capacity has not yet been established, the aim of our study was to develop a unique prediction formula for peak heart rate (HR) that can be used in this population.
Methods: This cross-sectional study measured physical function and HR at peak exercise and anaerobic threshold (AT) during cardiopulmonary exercise tests in 126 individuals.
Kidney Int
May 2022
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Int Urol Nephrol
June 2022
Department of Nephrology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Purpose: Intradialytic exercise may improve dialysis efficiency; however, the association between changes in blood volume (BV) related to exercise intensity and solute removal kinetics remains unknown. We herein investigated the relationship between changes in BV with exercise and removal of solute molecules during hemodialysis.
Methods: Each of the 21 hemodialysis patients underwent cardiopulmonary exercise test to measure anaerobic threshold (AT).
Geriatr Gerontol Int
August 2021
Division of Cardiology, Kisen Hospital, Tokyo, Japan.
Background: Recently, social frailty has been increasingly recognized as a factor associated with adverse health outcomes, including physical disability and mortality. However, there are no studies about the importance of this factor among hemodialysis patients. Therefore, we investigated the relationship between social frailty and early physical dysfunction in this group of patients.
View Article and Find Full Text PDFEur J Med Res
February 2021
Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kamimachi, Itabashi-Ku, Tokyo, 173-8610, Japan.
Background: Patients with severe COVID-19 have disorders of the respiratory, cardiovascular, coagulation, skeletal muscle, and central nervous systems. These systemic failures may be associated with cytokine release syndrome, characterized by hyperpyrexia, thrombocytopenia, hyperferritinemia, and the elevation of other inflammatory markers. Rhabdomyolysis with high fever is a complication that is rarely found in COVID-19.
View Article and Find Full Text PDFOpen Med (Wars)
December 2017
Division of Laboratory Medicine, Department of Pathology and Microbiology, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
Myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis (MPO-AAV) does not usually involve large vessels, such as the aorta. However, we experienced three cases having an aortic aneurysm as a complication of MPO-AAV with renal insufficiency. In one patient it involved the onset of descending aortic dissection during treatment for MPO-AAV; another two patients had an abdominal aortic aneurysm at the time of our diagnosis of MPO-AAV.
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