Awareness and Perceptions of the Impact of Tonsillectomy on the Level of Immunity and Autoimmune Diseases Among the Adult Population in Qassim, Saudi Arabia.

Introduction Tonsils are part of the immune system, but recurrent tonsillitis may necessitate tonsillectomy. While studies show that tonsillectomy reduces throat infections and improves quality of life, it does not significantly affect immunity or increase the risk of autoimmune diseases. Despite this, misconceptions about its impact persist.

Terson Syndrome in Two Infants: Case Report and Literature Review.

We report the presentation and outcome of Terson syndrome in four eyes of two infants in a tertiary hospital in Saudi Arabia. This is a retrospective report of two infants with Terson syndrome due to accidental traumatic head injuries. Intraoperative screenshots of the posterior pole were taken for both cases.

Exploring the Impact of Digital Health Tools in Enhancing Quality of Life and Psychological Adjustment in Long-term Blood Donors: A Cross-Sectional Study.

Background: Blood donation plays a critical role in public health, yet long-term donors (donating at least twice per year, for at least three years) often face challenges related to psychological adjustment and quality of life. Digital health tools could offer innovative solutions to address these issues by providing personalized support, tracking, and mental health interventions.

Aim: This study investigates the impact of digital health tools on the quality of life (QoL) and psychological adjustment of long-term blood donors in Saudi Arabia, with attention to demographic factors influencing engagement and perceptions.

Patient Safety Attitudes Among Saudi Medical Students and Interns: Insights for Improving Medical Education.

Purpose: Patient safety (PS) is a basic principle of healthcare worldwide. In Saudi Arabia, medical colleges have integrated PS modules into their regular curricula. This study investigated undergraduate medical students' and interns' attitudes regarding PS at King Abdulaziz University (KAU), Jeddah.

Comparisons of the Academic Performance of Medical and Health-Sciences Students Related to Three Learning Methods: A Cross-Sectional Study.

Introduction: The learning methods employed in medical education have substantially transformed from traditional face-to-face (FTF) instruction to online learning modalities. This study sought to quantitatively compare the impact of three learning methods on the academic performance of first-year medical and health sciences students enrolled in a Medical Terminology (MT) course. The learning methods examined include the FTF method, the online-synchronized method, and a blended learning method that combines elements of both.

Pharmacogenomics for neurodegenerative disorders - a focused review.

Neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) are characterized by the progressive degeneration of neuronal structure and function, leading to severe cognitive and motor impairments. These conditions present significant challenges to healthcare systems, and traditional treatments often fail to account for genetic variability among patients, resulting in inconsistent therapeutic outcomes. Pharmacogenomics aims to tailor medical treatments based on an individual's genetic profile, thereby improving therapeutic efficacy and reducing adverse effects.

Motor skill experience modulates attentional processing regardless of open- or closed-skill types: an ERP study.

Background: Attentional engagement, the ability to maintain focus on relevant tasks, plays a crucial role in optimizing human performance. Studies have shown that athletes exhibit superior attentional engagement compared to non-athletes; however, it remains unclear if these benefits persist in non-sport-related tasks or differ across types of sports expertise, such as open-skill versus closed-skill sports.

Methods: Ninety-three young adults, divided into open-skill athletes ( = 31), closed-skill athletes ( = 31), and a control group ( = 31), completed an auditory oddball task while the P3 component of event-related potentials was measured to assess attentional processing.

Effectiveness of picture exchange communication system in developing requesting skills for children with multiple disabilities.

This study evaluated the effectiveness of the Picture Exchange Communication System (PECS) in developing and generalizing requesting skills among children with multiple disabilities. The study was conducted at The Autism Center of Excellence, Riyadh, Saudi Arabia. This study included three participants age ranged from 4.

Augmenting phyto-chemical and phyto-mineral profiling of moringa leaf extract: A contrastive study of solid-liquid extraction methodologies.

The global food system is plagued by legitimacy and stability issues due to climate and ecosystem disruptions, contributing to widespread malnutrition. A significant portion of the global population experiences undernourishment, overweight, and micronutrient deficiencies from unhealthy diets. Addressing these challenges necessitates regular consumption of essential nutrients from plant sources.

Using MaxEnt modeling to analyze climate change impacts on van Hall, 1904 distribution on the global scale.

is a pathogenic bacterium that poses a significant threat to global agriculture, necessitating a deeper understanding of its ecological dynamics in the context of global warming. This study investigates the current and projected future distribution of , focusing on the climatic factors that influence its spread. To achieve this, we employed Maximum Entropy (MaxEnt) modeling based on Geographic Information Systems (GIS) to analyze species occurrence records alongside relevant climate data.

Comparison of the efficacy of curcumin and its nano formulation on dexamethasone-induced hepatic steatosis, dyslipidemia, and hyperglycemia in Wistar rats.

Background And Objective: Insulin resistance is a primary feature of type 2 diabetes. This study compared the effects of curcumin and its nanoformulation on insulin resistance, fasting blood sugar, liver function, GLUT4, lipid profile, and oxidative stress in the liver and pancreas in a diabetic model.

Methods: Thirty male Wistar rats were divided into five groups: a control group, a diabetic group, a diabetic group treated with metformin (40 mg/kg), a diabetic group treated with curcumin (100 mg/kg), and a diabetic group treated with curcumin NPs (100 mg/kg).

Predictive analytics technique based on hybrid sampling to manage unbalanced data in smart cities.

A smart city is deemed smart enough because it has the capability to make decisions on its own. Artificial intelligence needs a lot of data from the physical world to make correct decisions. IoT sensor devices collect data from the surroundings, which is further used for predictive analytics.

Optimization and assessment of a hybrid geothermal heat pump and wind turbine system in Izmir, Turkey: A 4E analysis approach.

This study explores the optimization and performance of a hybrid energy system combining a geothermal heat pump (GHP) with a wind turbine in Izmir, Turkey. Utilizing a 4E (Energy, Exergy, Economic, and Exergoenvironmental) analysis approach, the system aims to enhance winter heating efficiency. Geothermal heat pumps leverage the Earth's consistent temperatures for heating and cooling, offering a sustainable alternative to traditional energy sources.

Empowering data-driven load forecasting by leveraging long short-term memory recurrent neural networks.

The integration of renewable energy sources has resulted in an increasing intricacy in the functioning and organization of power systems. Accurate load forecasting, particularly taking into account dynamic factors like as climatic and socioeconomic impacts, is essential for effective management. Conventional statistical analysis and machine learning methods struggle with accurately capturing the intricate temporal relationships present in load data.

Role of Nrf2/HO-1 and cytoglobin signaling in the protective effect of indole-3-acetic acid and chenodeoxycholic acid against kidney injury induced by valproate.

Background: Purpose: Valproate (VPA) is an antiepileptic drug widely used to treat various psychiatric and neurological disorders. Although its use is generally considered safe, chronic administration may lead to kidney injury. The mechanisms underlying VPA kidney toxicity are not entirely explored.

Prevalence of polycystic ovary syndrome among infertile women in the Gulf Cooperation Council (GCC) countries: A systematic review and meta-analysis.

Background: Polycystic ovary syndrome (PCOS) is a significant contributor to female infertility and other various metabolic disorders. This systematic review estimates the prevalence of PCOS among infertile women in the Gulf Cooperation Council (GCC) countries.

Methods: The study searched five databases (PubMed, Embase, CINAHL, Web of Science, and SCOPUS), from their inception to 2022 for observational studies conducted in GCC countries.

Phytochemical diversity, therapeutic potential, and ecological roles of the genus.

The genus , a pivotal component of Neotropical flora, is renowned for its integration of traditional medicinal uses with significant ecological functions. This review aims to highlight the phytochemical diversity and pharmacological activities of the genus, with a particular focus on well-documented species such as , , and . Through a comprehensive review of the literature and current studies, this review identifies critical phytochemicals, including flavonoids, phenolic acids, and terpenoids, and correlates these compounds with biological activities such as anti-inflammatory, antimicrobial, and antioxidant effects.

A significance of micro-motile organism's flow of nanofluid for heat transportation with thermal radiations.

The ability of nanofluids to improve heat transmission in thermal systems is well established. This work investigates the three-dimensional theoretical behavior of Darcy-Forchheimer nanofluids in tilted magnetohydrodynamics. In this study, the Soret effect, micro-motile organisms, thermophoresis, and heat radiation are also considered.

Advanced deep transfer learning techniques for efficient detection of cotton plant diseases.

Introduction: Cotton, being a crucial cash crop globally, faces significant challenges due to multiple diseases that adversely affect its quality and yield. To identify such diseases is very important for the implementation of effective management strategies for sustainable agriculture. Image recognition plays an important role for the timely and accurate identification of diseases in cotton plants as it allows farmers to implement effective interventions and optimize resource allocation.

Inoculation with sp. enhances carbohydrate and amino acid production, strengthening antioxidant metabolism to mitigate heat stress in wheat cultivars.

Introduction: Heat stress caused by global warming adversely affects wheat yield through declining most nutritional quality attributes in grains, excluding grain protein content.

Methods: This research investigated the biochemical, physiological, and antioxidant responses of wheat plants under heat stress, focusing on the role of plant growth-promoting bacteria ( sp.).

Viscosol Treatment Ameliorates Insulin-Mediated Regulation of Dyslipidemia, Hepatic Steatosis, and Lipid Metabolism by Targeting PTP1B in Type-2 Diabetic Mice Model.

Type 2 diabetes mellitus (T2DM), a metabolic disorder, has the hallmarks of persistent hyperglycemia, insulin resistance, and dyslipidemia. Protein-tyrosine phosphatase 1B (PTP1B) was found to be overexpressed in many tissues in the case of T2DM and involved in the negative regulation of insulin signaling. So, PTP1B inhibition can act as a therapeutic target for T2DM.

Impact of SWCNT-conjugated senna leaf extract on breast cancer cells: A potential apoptotic therapeutic strategy.

Breast cancer (BC) has a prevalence rate of 21.8% among Saudi women and ranks as the third leading cause of death in Western nations. Nanotechnology offers innovative methods for targeted BC therapy, and this study explores the use of single-walled carbon nanotubes (SWCNTs) for delivering the senna leaf extract.

Electrochemically embedded heterostructured Ni/NiS anchored onto carbon paper as bifunctional electrocatalysts for urea oxidation and hydrogen evolution reaction.

Developing high-efficiency, cost-effective, and long-term stable nanostructured catalysts for electrocatalytic water splitting remains one of the most challenging aspects of hydrogen fuel production. Urea electrooxidation reaction (UOR) can produce hydrogen energy from nitrogen-rich wastewater, making it a more sustainable and cheaper source of hydrogen. In this study, we have developed Ni/NiS hybrid structures with cauliflower-like morphology on carbon paper electrodes through the application of dimethylsulfoxide solvents.

Long-Term Remission Rate of Type 2 Diabetes Following Bariatric Surgery: A Retrospective Cohort Study in Adult Patients in Riyadh, Saudi Arabia.

Introduction Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder that poses significant health and economic burdens, particularly in regions like Saudi Arabia where prevalence rates are among the highest globally. Bariatric surgery has emerged as a promising intervention, not only for weight reduction but also for inducing diabetes remission. However, while the short-term benefits of the procedure are well documented, long-term outcomes remain under-explored, especially in Saudi populations.

Sultan's Score: A Novel Predictive Score to Predict Complete Response Following Drug-Eluting Bead Chemoembolization.

Background: Transcatheter arterial chemoembolization (TACE) is a well-known standard treatment for hepatocellular carcinoma (HCC); however, the effectiveness of this treatment can vary among patients.

Objectives: This study aimed to develop a novel imaging-based prediction score (Sultan's score) to predict complete response after treatment.

Methods: From January 2015 to 2021, 41 patients with solitary HCC, admitted at King Saud University Medical City, Riyadh, Saudi Arabia, were treated with drug-eluting TACE (DEBTACE).