Identifying subgroups of teacher burnout in elementary and secondary schools: the effects of teacher experience, age and gender.

Introduction: Teacher burnout is a serious problem that requires quick attention and management since it not only compromises educational quality but also strains schools' financial resources.

Research Objective: The purpose of the present study was to profile burnout indicators for teachers in the Kingdom of Saudi Arabia. A secondary goal was to evaluate the consistency of burnout profiles between elementary and secondary school teachers.

Obsessive-compulsive Symptoms Prevalence among Medical Students in Four Major Universities, Saudi Arabia: A Cross-Sectional Study.

Background: Obsessive-compulsive disorder is recognized by the World Health Organization as one of the top 10 most disabling disorders globally. Characterized by recurrent and persistent thoughts (obsessions) and/or repetitive behaviors (compulsions), it significantly disrupts an individual's daily life, impacting routine, education, career development, and social relationships. The disorder's prevalence varies worldwide, with studies in Saudi Arabia showing a higher rate of obsessive-compulsive symptoms among medical students.

Urine miRNA signature as potential non-invasive diagnostic biomarker for Hirschsprung's disease.

Hirschsprung's disease (HSCR) is characterized by congenital absence of ganglion cells in the gastrointestinal tract, which leads to impaired defecation, constipation and intestinal obstruction. The current diagnosis of HSCR is based on Rectal Suction Biopsies (RSBs), which could be complex in newborns. Occasionally, there is a delay in diagnosis that can increase the risk of clinical complications.

Characteristics and Associated Risk Factors of Neonatal Sepsis: A Retrospective Study From Saudi Arabia.

Introduction Neonatal sepsis is defined as a systemic illness caused by bacteria, viruses, or fungi, characterized by hemodynamic abnormalities and clinical findings that result in morbidity and mortality. Neonatal morbidity and mortality are significantly influenced by neonatal sepsis. Causative pathogens and antimicrobial sensitivity profiles have changed over time, with significant geographic variation.

ERS Congress 2024: highlights from the Thoracic Surgery and Lung Transplantation Assembly.

https://bit.ly/3AgC5Yv.

Median nerve entrapment neuropathy: a review on the pronator syndrome.

Pronator syndrome is a compression neuropathy of the median nerve within the anatomical structures of the elbow and forearm. It presents with neuropathic pain, numbness, and weakness of the forearm and hand, which are often exacerbated by repetitive pronation-supination movements. Patient presentation may mimic the signs and symptoms of carpal tunnel syndrome.

The use of Heated, Humidified, High-flow Nasal Cannulas, and Length of Hospital Stay Among Extremely Preterm Infants.

Background: Extremely preterm infants (EPIs) often require advanced respiratory support to survive, and one such intervention is the heated, humidified, high-flow nasal cannula (HHHFNC). While the use of this cannula in EPIs has been studied, the relationship between its use and the length of hospital stay is an important yet unexplored research area that we aim to investigate in this study.

Methods: In a quantitative retrospective cohort study, data were extracted from an electronic database.

Facial Lichen Planus Pigmentosus-Like Pigmentation Induced by Vicks VapoRub: A Case Report.

Lichen planus pigmentosus is a variant of lichen planus characterized by gray-brown hyperpigmented macules and patches occurring in sun exposed areas. Vicks VapoRub is an inhalant ointment frequently used to relieve symptoms of upper respiratory tract infections. We report a case of lichen planus pigmentosus induced by Vicks VapoRub and successfully treated with topical tacrolimus 0.

Evaluation of hypertension knowledge and its association with medication adherence among hypertensive patients attending primary health centers: a cross-sectional study from eastern Saudi Arabia.

Background And Aim: The global healthcare system acknowledged the crucial role of disease knowledge in health outcomes and improving quality of life among patients with chronic disease. A lack of adequate knowledge and understanding of hypertension, its symptoms, and available treatments can lead to poor treatment outcomes. The present study aimed to determine the level of hypertension knowledge and associated factors among hypertensive patients.

National Trends in Pulmonary Embolism Visit in United State Emergency Departments and Associated Costs (2006-2018).

Pulmonary embolism (PE) poses substantial morbidity and mortality risks, necessitating timely and accurate management in emergency departments (EDs). This study explores the trends in PE presentations to US EDs from 2006 to 2018 and assesses the impact of different factors on management and cost. This is a retrospective descriptive study conducted using the US Healthcare Cost and Utilization Project (HCUP) PE ED visits database.

eNSMBL-PASD: Spearheading early autism spectrum disorder detection through advanced genomic computational frameworks utilizing ensemble learning models.

Objective: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition influenced by various genetic and environmental factors. Currently, there is no definitive clinical test, such as a blood analysis or brain scan, for early diagnosis. The objective of this study is to develop a computational model that predicts ASD driver genes in the early stages using genomic data, aiming to enhance early diagnosis and intervention.

leaves extract-mediated synthesis of ZnO nanostructures for the enhanced photocatalytic oxidation of erythrosine.

This study was focused on the development of ZnO nanostructures for the efficient oxidation of erythrosine dye and for studying the antibacterial activity of ZnO. It was observed that the phytochemicals from leaves modified the size, shape, crystalline properties and surface chemical composition of the ZnO nanostructures. ZnO nanostructures synthesized with 15 mL leaves extract (S-15) demonstrated highly efficient oxidation of erythrosine dye under the illumination of natural sunlight.

Correction: Design, synthesis, and studies of new quinazolinones tagged thiophene, thienopyrimidine, and thienopyridine scaffolds as antiproliferative agents with potential p38α MAPK kinase inhibitory effects.

[This corrects the article DOI: 10.1039/D4RA06744D.].

Comparison of different severity scores in correlating hemoglobin levels with the severity of hepatic decompensation: An observational study.

Background: Chronic liver disease is a growing global health problem, leading to hepatic decompensation characterized by an array of clinical and biochemical complications. Several scoring systems have been introduced in assessing the severity of hepatic decompensation with the most frequent ones are Child-Pugh score, model of end-stage liver disease (MELD) score, and MELD-Na score. Anemia is frequently observed in cirrhotic patients and is linked to worsened clinical outcomes.

Experiences and overall impact reported by people living with obesity: results from a multinational study.

Objectives: To explore the impact of obesity on clinical outcomes, health-related quality of life, emotional well-being, and work productivity in people/patients with obesity across six countries by body mass index and the presence of complications.

Methods: Adelphi Real World Obesity Disease Specific Programme™ captured data related to physicians and their consulting people/patients with obesity on a weight management program or anti-obesity medication in Brazil, Canada, China, Japan, Kingdom of Saudi Arabia, and the United Arab Emirates from April to December 2022. Physicians reported data for up to eight qualifying people/patients with obesity.

Integrating Machine Learning and Pharmacophore Features for Enhanced Prediction of H1 Receptor Blockers.

Introduction: Histamine Type I Receptor Antagonists (H1 blockers) are widely used to mitigate histamine-induced inflammation, particularly in allergic reactions. Histamine, a biogenic amine found in endothelial cells, vascular smooth muscle, bronchial smooth muscle, and the hypothalamus, is a key player in these responses. H1 blockers are essential in cough syrups and flu medications and are divided into two generations: first-generation H1 blockers, which are sedating and have numerous side effects, and second-generation blockers, which are non-sedating and generally less toxic but may still exhibit cross-reactivity with other receptors.

Unlocking the Potential of miRNAs in Sepsis Diagnosis and Prognosis: From Pathophysiology to Precision Medicine.

The clinical syndrome appears as a dysregulated host response to infection that results in life-threatening organ dysfunction known as Sepsis. Sepsis is a serious public health concern where for every five deaths in ICU there is one patient who dies with sepsis worldwide. Sepsis is featured as unbalanced inflammation and immunosuppression which is sustained and profound, increasing patient susceptibility to secondary infections and mortality.

Resilience as a predictor of internet addictive behaviours: a study among Ghanaian and Saudi samples using structural equation modelling approach.

This study aimed to examine the relationship between resilience and internet addictive behaviours, focusing on cross-cultural contexts involving tertiary education students in Ghana and Saudi Arabia. Using a cross-sectional survey design, data were collected from 738 students across selected universities in both countries. Structural equation modeling (SEM) techniques were employed to analyse the data.

Barriers to nurse-led delirium management in intensive care units: an integrative systematic review using COM-B model.

Background: Development of effective guideline for delirium management is still seeking nowadays. As nurses are in the first confrontation line for delirium, their prospective in identifying barriers are essential in developing integrated strategies and clinical guidelines.

Objective: To explore the barriers focusing on intensive care unit (ICU) nurses' point of views to provide an evidence-based support for effective nurse-led delirium management in ICU settings.

Pattern of antibiotic dispensing at pharmacies according to access, watch, reserve (AWaRe) classification: multicenter study after COVID-19 waves in different districts of Pakistan.

Objective: The dispensing of non-prescription antibiotics is a worldwide concern, and antibiotics should only be dispensed with a legitimate prescription.

Methodology: A cross-sectional study was conducted using the simulated client methodology, with data collected, recorded, and analyzed using SPSS.

Results: The simulated client visited 210 pharmacies, of which 70 dispensed antibiotics without a prescription.

Evaluating dental students' satisfaction in clinical Periodontics courses at KSAU-HS: a cross-sectional study.

Background: The National Commission for Academic Accreditation and Assessment (NCAAA) in Saudi Arabia underscores the importance of assessing student satisfaction to ensure program quality. No previous studies have explored the satisfaction levels of dental students enrolled in clinical Periodontics courses at King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS). This study aims to assess dental students' satisfaction with clinical Periodontics courses and to explore potential differences in satisfaction based on gender and academic level.

Methylenetetrahydrofolate reductase () C677T and A1298C polymorphisms are associated with major depressive disorder in the Saudi patients attending Erada complex for mental health and Erada services - Jeddah, Saudi Arabia.

: Major Depressive Disorder (MDD) is a prevalent and debilitating mental disorder that has been linked to hyperhomocysteinemia and folate deficiency. These conditions are influenced by the methylenetetrahydrofolate reductase () gene, which plays a crucial role in converting homocysteine to methionine and is essential for folate metabolism and neurotransmitter synthesis, including serotonin. : This study explored the association between and polymorphisms among Saudi MDD patients attending the Erada Complex for Mental Health and Erada Services outpatient clinic in Jeddah, Saudi Arabia.

Leading Women in Respiratory Care: Letter From Saudi Arabia.

Special Series: Leading Women in Respiratory Clinical Sciences.

Privacy-preserving approach for IoT networks using statistical learning with optimization algorithm on high-dimensional big data environment.

In the present digital scenario, the explosion of Internet of Things (IoT) devices makes massive volumes of high-dimensional data, presenting significant data and privacy security challenges. As IoT networks enlarge, certifying sensitive data privacy while still employing data analytics authority is vital. In the period of big data, statistical learning has seen fast progressions in methodological practical and innovation applications.