Neutrophilic urticarial dermatosis without systemic disease: case report.

Neutrophilic urticarial dermatosis (NUD) is an uncommon and not well understood disease. We report a 24-year-old female with persistent present with pruritic and painful urticarial plaques unresponsive to convential treatment. Histopathologically, it demonstrates a perivascular and interstitial neutrophilic infiltrate with leukocytoclasia without evidence of vasculitis or dermal edema consistent with neutrophilic urticarial dermatosis.

Toxic epidermal necrolysis induced by COVID-19.

Toxic epidermal necrolysis (TEN) is a life-threatening acute mucocutaneous syndrome. It is characterized by keratinocyte necrosis and apoptosis, which affect more than 30% of the body's surface. TEN is most commonly due to an altered immunological response to specific drugs, infections, and malignancies, or it can be idiopathic.

Factors Associated with Recurrent Emergency Department Visits for Epistaxis in Adults, Cross Sectional Study in Two Tertiary Care Hospitals in Riyadh, Saudi Arabia.

Introduction And Objectives: This study aimed to investigate the prevalence of recurrent and active epistaxis in adult patients presenting to the Emergency Department (ED) and explored the association of recurrent epistaxis with demographic characteristics, comorbidities and medications, and types of emergency interventions in adult epistaxis patients.

Methods: A retrospective cross-sectional study was conducted with data from Eds of two tertiary hospitals over three years, from January 2019 to January 2022. All adult patients aged ≥18 years with active epistaxis not resolved by pressure on the nose or head positioning were included.

Nutritional Support in the ICU.

Critical illness is a complex condition that can have a devastating impact on health and quality of life. Nutritional support is a crucial component of critical care that aims to maintain or restore nutritional status and muscle function. A one-size-fits-all approach to the components of nutritional support has not proven beneficial.

Pharmacological Profiling of and : Unraveling the Antibacterial and Anti-Cancer Potential of Chemically Active Metabolites.

The increasing prevalence of cancer and bacterial resistance necessitates more effective anti-cancer and anti-bacterial treatments. This study explores the potential of medicinal plants, specifically () and (), in addressing this need, aiming to uncover new therapeutic interventions. Various extraction methods for the leaves of and were employed to investigate the anti-bacterial and anti-cancer properties of these herbs.

A Narrative Review of Rotator Cuff Tear Management: Surgery Versus Conservative Treatment.

Rotator cuff tears are a prevalent musculoskeletal issue, particularly among middle-aged and elderly individuals, affecting shoulder stability and arm movement. These tears can arise from acute injuries or chronic wear and tear, leading to conditions ranging from tendinopathy to cuff tear arthropathy. The prevalence increases with age, with a significant portion of older adults affected, many of whom may be asymptomatic.

Social Media Use and Body Image Dissatisfaction Among University Students of Health Sciences in Saudi Arabia.

Background Recently, social media has become an integral part of daily life, particularly among young adults. While these platforms offer numerous benefits, including communication, information sharing, and social connection, they have also been linked to a range of negative psychological consequences, including body image dissatisfaction. This study examined the prevalence of body dissatisfaction among health science students in Saudi Arabia, assessed the frequency and duration of social media use by gender, estimated the impact of social media use for >3 hours a day on body dissatisfaction, and identified the most commonly used social media platforms.

Assessing the Causes of Acceptance or Refusal of Breast Cosmetic Procedures Among Saudi Women When They Get to Age of Menopause: A Cross Sectional Study-Saudi Arabia.

Introduction: Cosmetic breast surgery encompasses a variety of procedures aimed at enhancing breast appearance and is increasingly popular globally. Despite this trend, the acceptance of such surgeries among Saudi women approaching menopause remains understudied. This research aims to explore the attitudes and perceptions toward cosmetic breast surgery in this demographic, considering cultural and religious influences in Saudi Arabia.

Efficacy of Duloxetine for Postspine Surgery Pain: A Systematic Review and Meta-Analysis.

Background: Duloxetine, a serotonin and norepinephrine reuptake inhibitor (SNRI), is used to treat various health conditions, including major depressive disorder, generalized anxiety disorder, fibromyalgia, and off-label for chemotherapy-induced pain. We conducted this systematic review and meta-analysis aiming to test the current evidence regarding effectiveness and safety of duloxetine for postspine surgeries pain.

Methods: We searched the Cochrane Central Register of Controlled Trials, PubMed, Scopus and Web of science databases for relevant articles up to March 2024.

A nationwide cross-sectional study in Saudi Arabia for the assessment of understanding and practices of clinicians towards personalized genetic testing.

In order to plan and facilitate the culture of personalized / precision medicine in medical practices within any healthcare institution, it is requisite for healthcare professionals like clinicians to have a clear understanding and approach towards the practices of personalized genetic testing. This nationwide cross-sectional study aimed to measure the perceptions and knowledge of clinicians towards personalized genetic testing and assess their current practices of personalized genetic testing in clinical settings through an online self-administered questionnaire in Saudi Arabia. The results of the study revealed that almost two-fifths of participants were responsible for ordering genetic tests directly (39.

Prevalence of Patellofemoral Pain Among Adults in Saudi Arabia.

Background And Aim: Patellofemoral pain syndrome (PFPS) is a disease that clinically presents with retro-patellar and peripatellar pain that affects primarily physically active individuals. This study aims to estimate the prevalence of PFPS in Saudi Arabia and the variables that contribute to its occurrence.

Objectives: This multicenter, cross-sectional study aimed to explore the prevalence of patellofemoral pain in Saudi Arabia.

Bibliometric Analysis of Peer-Reviewed Literature on Erosive Tooth Wear From 1945 to 2023.

Erosive tooth wear (ETW) is a prevalent oral condition with varying etiology, including erosion, abrasion, abfraction, and attrition. It is reported in the literature in different nomenclatures, hindering the ability to identify the emerging trends and influential scholarly works and bodies within this field. Using a bibliometric analysis approach, this study aims to evaluate the trends, themes, and productivity of the research on ETW condition while respecting its different terminologies.

Assessment of cardio-oncology knowledge and practice among healthcare providers in Saudi Arabia: a comprehensive nationwide survey.

Introduction: The evolving field of oncology necessitates effective management of cancer-related cardiovascular diseases. In Saudi Arabia, the incidence of cancer is rising, and there is a critical need for cardio-oncology services to address cancer treatment-related cardiovascular toxicity. This study aimed to evaluate the knowledge and practices of healthcare providers (HCPs) in Saudi Arabia regarding cardio-oncology.

Post-COVID-19 manifestations among college students: shedding the light on young adults' health.

Background: Post-COVID-19 syndrome refers to a variety of symptoms that affect different organs in the body and can persist 28 days following exposure to COVID-19. Previous studies have shown that COVID-19 affects not only elderly individuals but also young adults. However, the influence of post-COVID-19 syndrome on young adults has not been studied sufficiently.

The Prevalence of Vitamin B12 Deficiency Among Diabetic Patients Who Use Metformin.

Background And Aim: Vitamin B12 deficiency is a recognized concern among patients with type 2 diabetes mellitus (T2DM) using metformin due to its potential impact on health outcomes. This study investigates the prevalence of vitamin B12 deficiency among diabetic patients using metformin at Dr. Sulaiman Al Habib Medical Group (HMG) hospitals.

Risk of malignancy and the use of disease-modifying therapy in multiple sclerosis: exploring the role of DMT in a multi-center study.

Background: The potential link between disease-modifying therapies (DMTs) and malignancy in multiple sclerosis (MS) patients has generated significant concern, particularly given the immunosuppressive nature of these treatments. Conflicting evidence in the literature has left this issue unresolved, underscoring the need for definitive research to inform clinical practice. This study addresses this gap by examining cancer occurrence among MS patients on DMTs treated at two tertiary-care centers in Saudi Arabia.

Incidence of Proteinuria Post Radical Nephrectomy in Comparison to Partial Nephrectomy: A Comparative Study.

Objectives The objective of this study is to enhance understanding of the incidence and impact of proteinuria following nephrectomy, to guide clinical decision-making, and to optimize post-operative monitoring strategies. Specifically, the study seeks to compare the incidence of proteinuria in patients undergoing radical nephrectomy and those receiving partial nephrectomy, thereby contributing valuable insights into post-surgical outcomes that could inform treatment approaches and improve patient care. Methods It is a retrospective cohort design, analyzing clinical data from patients who underwent radical or partial nephrectomy in King Abdulaziz Medical City (KAMC), Riyadh, Saudi Arabia, between 2014 and 2022.

Age-specific vulnerability and high prevalence of delirium in pediatric intensive care based on a prospective cohort study.

Delirium, a neuropsychiatric syndrome characterized by acute disruptions in attention and awareness, significantly impacts children in Pediatric Intensive Care Units (PICUs), leading to prolonged hospitalization, increased infection risk, and dependence on mechanical ventilation. Despite growing recognition, its true burden and risk factors in children remain poorly understood. This prospective cohort study investigated the prevalence, characteristics, and potential therapeutic targets for delirium in 890 children admitted to a tertiary PICU between January and December 2022.

Exploring Pediatric Sutural Variations with 3D CT Imaging: A Retrospective Study at a Tertiary Hospital.

Background: Sutural anatomy variation has long been a topic of debate among anatomists, paleontologists, and morphologists. While the exact reasons for the prevalence of this variance remains a topic of ongoing discussion, developmental and genetic factors are hypothesized to be the main reasons. Understanding the morphology and occurrence of normal sutural variations in pediatric patients is essential to making the right diagnosis, where a misinterpretation of a sutural bone may lead to an inaccurate assessment, completely misleading the diagnostic process.

Prognostic Value of Strain by Speckle Tracking Echocardiography in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy.

Background Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare genetic disorder associated with an elevated risk of life-threatening arrhythmias and progressive ventricular impairment. Risk stratification is essential to prevent major adverse cardiac events (MACE). Our study aimed to investigate the incremental value of strain measured by two-dimensional speckle-tracking echocardiography in predicting MACE in ARVC patients compared to conventional echocardiographic parameters.

Effect of Mechanical Surface Treatment on Shear Bond Strength of Orthodontic Brackets to 3D Printed and Milled CAD/CAM Provisional Materials: An In Vitro Study.

The aim of the study is to assess the impact of mechanical surface treatments on the shear bond strength (SBS) of orthodontic brackets bonded to three-dimensional (3D) printed and milled CAD/CAM provisional materials. Sixty cylindrical samples were fabricated for each provisional material. Samples were treated with one of the following surface treatments: aluminum oxide airborne particle abrasion, diamond bur rotary instrument roughening, and phosphoric acid etching (control).

Comparison of Three-Bag Method Acetylcysteine Versus Two-Bag Method Acetylcysteine for the Treatment of Acetaminophen Toxicity: An Updated Systematic Review and Meta-Analysis.

Background: Acetaminophen is generally considered safe when used according to the recommended guidelines. Consumption in excessive doses can lead to severe liver damage and, in critical cases, may even result in death. To reduce the effects of acetaminophen overdose, N-acetylcysteine (NAC) has been established as the preferred intervention to prevent liver damage.

Congenitally Missing Lateral Incisors: Prioritizing Space Closure Whenever Feasible.

Congenital missing teeth are among the most prevalent dental malformations. Maxillary lateral incisors are particularly prone to agenesis, often missing bilaterally. This condition presented complex challenges for both patients and clinicians.

Exploring Spine Surgeons' Perspectives on Salah (Islamic prayer) Performance Post-Surgery. Time for consensus?

Background: Post-surgical recovery following spine surgeries poses challenges for Muslim patients wishing to resume Salah (Islamic prayer), which involves physical movements like kneeling and prostration. This study aims to examine spine surgeons' perspectives on the appropriate timing and conditions for resuming Salah after spine surgery without restrictions.

Methods: This cross-sectional survey study included surgeons in Saudi Arabia who perform spine surgeries.

Exploring the Influence of Genetic Single-Nucleotide Polymorphism (SNPs) on Endodontic Pathologies: A Comprehensive Review.

A considerable portion of the global population is affected by pulpitis and periapical lesions. While the impact of infections caused by various microbes and host effector molecules in pulpal and periapical diseases is widely recognized, disease susceptibility and progression are also influenced by the dynamic interaction between host genetic factors and environmental influences. Apical periodontitis occurs as an inflammatory response to microorganisms present in the root canals of infected teeth.