Emergence of novel methicillin-resistant strains in a tertiary care facility in Riyadh, Saudi Arabia.

Purpose: There is a need for continuous surveillance of methicillin-resistant (MRSA) to identify emergence of new strains. We hypothesize that MRSA strains are evolving with ongoing acquisition of SCC elements. This study was carried out to evaluate the evolution of MRSA at a tertiary care facility in Saudi Arabia.

Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review.

Paneth cells are classified as secretory cells which are normally found in the cecum and ascending colon. Their presence in other parts of the gastrointestinal tract is regarded as abnormal and indicates metaplasia. Paneth cells may also be rarely found in gastrointestinal, biliary and prostatic tumors.

Genotyping of Staphylococcus aureus associated with nasal colonization among healthcare workers using DNA microarray.

Introduction: Healthcare workers (HCWs) colonized with Staphylococcus aureus may serve as a reservoir of infection. This study was carried to determine the genetic make-up of S. aureus nasal colonizers in HCWs.

Investigating a rare methicillin-resistant strain: first description of genome sequencing and molecular characterization of CC15-MRSA.

Purpose: Methicillin resistant CC15 strains (CC15-MRSA) have only been sporadically described in literature. This study was carried out to describe the genetic make-up for this rare MRSA strain.

Methods: Four CC15-MRSA isolates collected in Riyadh, Saudi Arabia, between 2013 and 2014 were studied.

Diversity of methicillin-resistant Staphylococcus aureus CC22-MRSA-IV from Saudi Arabia and the Gulf region.

Objectives: CC22-MRSA-IV, UK-EMRSA-15/Barnim EMRSA, is a common and pandemic strain of methicillin-resistant Staphylococcus aureus (MRSA) that has been found mainly in Western Europe, but also in other parts of the world including some Gulf countries. One suspected case of an infection with this strain in a patient who was admitted to the surgical unit in Riyadh, Kingdom of Saudi Arabia (KSA) was investigated in order to check whether this strain has reached KSA.

Methods: Besides the index isolate, 46 additional isolates of CC22-MRSA-IV from patients from KSA, Abu Dhabi, Kuwait, and Germany (patients with a history of travel in the Middle East), were characterized by microarray hybridization.

Molecular characterization of methicillin-resistant Staphylococcus aureus in nosocomial infections in a tertiary-care facility: emergence of new clonal complexes in Saudi Arabia.

Changes in the molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) continue to be reported. This study was carried out to characterize MRSA isolates in Saudi Arabia. MRSA isolates causing nosocomial infections (n = 117) obtained from 2009-2015 at a tertiary-care facility in Riyadh, Saudi Arabia, were studied.

The Prevalence of Anxiety and Depression in Arab Dermatology Patients.

Background: Psychiatric disorders are common among patients with physical illnesses.

Objectives: To estimate the prevalence of anxiety and depression in Arab dermatology patients and to study its association with the patients' characteristics.

Materials And Methods: A cross-sectional study was carried out on 875 patients attending the Dermatology Clinic at King Khalid University Hospital in Riyadh, Saudi Arabia.

Successful treatment of gastrointestinal basidiobolomycosis with voriconazole without surgical intervention.

Basidiobolomycosis is a rare disease due to fungus Basidiobolus ranarum, an environmental saprophyte that is found worldwide, though mainly reported in the tropical and subtropical regions. Basidiobolomycosis is an unusual fungal skin infection, rarely involves the gastrointestinal (GI) tract. Most of the cases of paediatric GI basidiobolomycosis (GIB) were reported from the southern region of Saudi Arabia.

Unusual clinicopathological and immunological presentation of chronic bullous dermatosis of childhood (linear IgA dermatosis).

Linear IgA bullous dermatosis is a rare sulfone-responsive subepidermal blistering disorder of unknown etiology in which smooth linear deposits of IgA are found in the basement membrane zone. Chronic bullous dermatosis of childhood is equivalent to linear IgA disease of adulthood and is characterized by an abrupt onset of large, widespread and tense bullae on a normal or erythematous base. In this case, we describe an unusual presentation of chronic bullous dermatosis in a 14-month-old Saudi girl.

Immunophenotyping of acute lymphoblastic leukemia using immunohistochemistry in bone marrow biopsy specimens.

Flow cytometry is the preferred method of diagnosing and immunophenotyping acute lymphoblastic leukemia (ALL). However, there are situations in which immunohistochemical staining (IH) of bone marrow trephine biopsy specimens can be used to provide immunophenotypic information. To evaluate the use of IH and to confirm its value in diagnosing and typing of ALL, we studied 50 cases of denovo ALL that were previously classified into pre B, T and B by morphologic, cytochemical and FC methods.

Recent advances in the management of hypertension.

Hypertension is a worldwide prevalent disease that leads to considerable morbidity and mortality. While its underlying basis of genetics and pathology as well as its complications are universally agreed upon, management of hypertension remains to be controversial. In this article, we will present clear evidence of the recent advances in the management of hypertension that include newer therapeutic agents replacing old strategies.

Dyspnea, pulmonary function and exercise capacity in adult Saudi patients with sickle cell disease.

Objective: To examine pulmonary function, dyspnea and exercise capacity in adult Saudi sickle cell disease (SCD) patients.

Methods: The patients were recruited from the hematology clinic at King Khalid University Hospital in Riyadh from January to December 2005. The study involved 39 patients with stable SCD (20 women and 19 men), with a mean age of 22.

Placental migration and mode of delivery in placenta previa: transvaginal sonographic assessment during the third trimester.

Background: The objective of this study was to assess the role of serial transvaginal sonography (TVS) in predicting placental migration and mode of delivery in pregnancy complicated by placenta previa during the third trimester.

Patients And Methods: In this prospective observational study, all the cases had confirmed diagnosis of placenta previa before 32 weeks' gestation. TVS was performed between 28 and 32 weeks' gestation for 287 patients with either clinical suspicion or previous sonographic diagnosis of placenta previa.

The prevalence of obesity and overweight in 1-18-year-old Saudi children.

Objectives: The aim of this study was to review the prevalence of overweight and obesity in Saudi children with ages ranging up to 18 years.

Subjects And Methods: The study was a cross-sectional national epidemiological household survey, and the study group included 12071 children (boys 6281; girls 6420), with ages ranging from 1-18 years. Their height and weight were measured and body mass index (BMI) was calculated.