1,159 results match your criteria: "King Fahad hospital[Affiliation]"

Background: Medical curriculum reform requires quality assurance in all curricular activities including assessment. Such reform necessitates a shift of focus from summative assessment (SA) to formative assessment (FA). However, the implementation of FA confronts several challenges that hinder its proper application, especially with the increased number of students and the diversity of activities required from faculty members.

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The popliteal arteries are rarely injured during total knee replacement. Although uncommon, these complications warrant attention because the consequences can be disastrous, with high mortality rates, amputation risk, and additional comorbidities such as foot drop, infection, and functional impairment. However, it has detrimental consequences for the patient.

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Introduction: Thyroid disorders are a common manifestation of hormonal disorders that result from either excessive or insufficient production of thyroid hormones and the swelling of the thyroid gland. A lack of information and awareness of the signs and risk factors of thyroid problems can lead to untreated patients, thereby harming public health.

Methods: Observational cross-sectional research was conducted in the Al-Baha region of Saudi Arabia, with 531 residents selected from the general population.

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Androgenetic alopecia is a chronic dermatological condition in which genetically predisposed individuals undergo progressive hair loss secondary to the effects of circulating androgens. It has been well documented that dihydrotestosterone binds to the androgenic receptors prevalent in the scalp, thus inducing miniaturization of the hair follicle. To date, the only FDA approved medications for the treatment of androgenetic alopecia are finasteride and minoxidil.

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Assessing radiation doses and proposing DRLs for nuclear medicine procedures for pediatric and adult patients in Madinah, Saudi Arabia.

Appl Radiat Isot

January 2025

Applied Physics and Radiation Technologies Group, CCDCU, School of Engineering and Technology, Sunway University, Bandar Sunway, Selangor, 47500, Malaysia; Faculty of Graduate Studies, Daffodil International University, Daffodil Smart City, Birulia, Savar, Dhaka, 1216, Bangladesh; Department of Physics, College of Science, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. Electronic address:

Background: Nuclear medicine diagnostic and treatment procedures represent significant sources of ionizing radiation exposure for both staff and patients. Consequently, assessing and optimizing radiation doses are crucial to minimize potential side effects.

Aim: This study seeks to evaluate the effective radiation doses associated with common diagnostic and treatment procedures, as well as propose diagnostic reference levels (DRLs), within two nuclear medicine centers in Madinah, Saudi Arabia.

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Proton beam radiation therapy (PBRT) is an advanced cancer treatment modality that utilizes the distinctive physical properties of protons to precisely deliver radiation to tumor targets while sparing healthy tissue. This cannot be obtained with photon radiation. In this systematic review and meta-analysis, we aimed to comprehensively assess the risk of brainstem toxicity in pediatric brain tumor patients undergoing PBRT.

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Background: Evidence-based practice (EBP) lowers costs, guarantees staying current with new technology and abilities, and enables the provision of high-quality care. Evidence-based practice (EBP) considered the foundation for safe patient care.

Aim: is to validate and carry out the linguistic-cultural adaptation of the S-EBPQ for the Arabic language.

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Dengue virus (DENV) remains one of the most common arboviral infections threatening humans. This study was conducted to systematically review the available literature and provide an updated overview of the overall prevalence of DENV infection in Saudi Arabia. The prevalence data was pooled from 21,891 participants recruited in 17 studies.

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Background: Falls are a common and consequential concern for persons with multiple sclerosis (PwMS), with trunk impairment frequently observed even in the early stages of the disease. However, the relationship between falls and trunk impairment using the trunk impairment scale in this population remains unclear. This study aims to explore this association and identify potential factors contributing to falls in PwMS.

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COVID-19 infection in children with blood cancer: A systematic review.

Ann Hematol

November 2024

Molecular Diagnostic Laboratory, Johns Hopkins Aramco Healthcare, 31311, Dhahran, Saudi Arabia.

Article Synopsis
  • * The study aimed to assess the incidence of COVID-19 among children with blood cancer, analyzing their demographics, clinical features, and the outcomes of their treatments.
  • * Out of 3077 identified studies, 155 were included in the review, involving 1289 children with blood cancer and confirmed COVID-19, showing that the majority had relatively mild symptoms, while a minority faced severe complications or death.
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  • - Foreign bodies in the lower urinary system, though rare, can lead to pain, blood in urine, or infections, with diagnosis typically confirmed through clinical examination and pelvic X-ray.
  • - A case study describes a 25-year-old male who experienced pain after inserting a wire into his urethra, which was found coiled and knotted in his bladder during an X-ray.
  • - Treatment involved a successful open cystostomy to remove the wire, and a psychiatric evaluation was recommended since foreign body cases are often linked to psychological issues.
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This systematic review synthesizes current evidence to evaluate the safety and efficacy of inclisiran for lowering low-density lipoprotein cholesterol (LDL-C). A thorough search was conducted across four main databases - PubMed, Web of Science, SCOPUS, and Science Direct - for relevant studies published in the literature within the last five years (2020-2024). We included seven studies with a total of 6831 participants, of which 4661 (68.

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  • - Metabolic changes in tumor cells shift towards glycolysis or mitochondrial respiration depending on tumor progression, with mitochondrial dysfunction driving these changes and influencing tumor growth.
  • - Mutations in mitochondrial DNA (mtDNA) have been found in tumors like glioblastoma, but many studies focus on limited parts of mtDNA, potentially missing significant mutations that affect tumor behavior.
  • - Mitochondrial dysfunction impacts energy production and various signaling pathways in tumor cells, marking them as potential targets for new therapies to combat chemoresistance in glioblastoma.
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  • Psoriasis is a lifelong skin condition, and Tofacitinib, a type of JAK inhibitor, may help improve skin lesions and overall patient outcomes, but it also carries risks like increased infections due to its immunosuppressive nature.
  • A systematic review and meta-analysis were conducted, following specific guidelines, to compare the safety of Tofacitinib against placebo, focusing on the occurrence of serious infections and other adverse effects among participants.
  • Among 998 studies, only six randomized controlled trials with 2,516 psoriasis patients were included; the results indicated increased risks of herpes zoster and respiratory infections, but no significant differences in safety outcomes were found between those taking Tofacitinib and those receiving a placebo
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Hydroxyurea (HU) is an effective medication used to reduce the frequency of painful crises associated with sickle cell disease (SCD). However, data describing its prevalence among SCD patients in the Eastern Region of Saudi Arabia are scarce. This is a multi-center, retrospective, cross-sectional study that aims to investigate the pattern of prescribing HU in SCD patients and to determine the association between prescribing HU and other co-prescribed medications used to manage SCD complications.

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Objectives: Accurate estimation of unerupted permanent canines and premolars is a crucial step for effective orthodontic treatment planning during mixed dentition. This study aimed to evaluate the validity of Moyers' charts and the Tanaka-Johnston equation in predicting tooth sizes in a sample of the Madina population in Saudi Arabia and propose a new regression equation.

Methods: Dental casts from 219 subjects (113 males and 106 females) were analyzed.

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Efficacy of pCONUS Devices in the Management of Intracranial Aneurysms: Outcomes of 190 Patients.

Cureus

September 2024

Department of Neurology and Interventional Radiology, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

Intracranial aneurysms (IAs) pose a significant health concern, necessitating effective treatment modalities. The pCONUS device has emerged as a promising option for managing complex IAs, particularly wide-necked bifurcation aneurysms. Evaluating its efficacy across multiple studies is essential for establishing therapeutic guidelines.

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  • - NHMH is a benign reactive condition marked by an increase in histiocytic and scattered mesothelial cells, presented here in a 56-year-old HIV-positive male who had swelling and nodules in the greater omentum.
  • - The patient was found to have an abnormal CD4/CD8 ratio and underwent surgery, with biopsies confirming the diagnosis through histopathological examination and immunohistochemical staining.
  • - This case is notable for being the first report of NHMH in an HIV-positive patient, highlighting its potential to appear malignant on imaging, underscoring the need for accurate diagnosis to avoid incorrect treatment.
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Background/aim: Earlier treatment in axial spondyloarthritis (axSpA) was proposed to alter disease prognosis in this often-challenging condition. We aimed to assess the proportion of patients and prognostic factors associated with axSpA remission.

Objective: The aim was to determine the number of patients with Ankylosing Spondylitis Disease Activity Score with C-reactive protein (ASDAS-CRP) of <2.

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This case report describes the successful management of a knotted ureteric stent in a 57-year-old male with diabetes mellitus, who presented with left flank pain and lower urinary tract symptoms after seven months of stent placement. Initial imaging revealed migration and encrustation of the stent, along with knotting at the proximal end. As rigid cystoscopy to attempt stent retrieval met resistance, a semirigid ureteroscope was used to laser transect the stent, allowing for the insertion of a new stent.

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Anatomical Study of Abdominal Wall Muscle Innervation to Optimize Retroperitoneal Vascular Approach.

Ann Vasc Surg

January 2025

Department of Vascular and Endovascular Surgery, Nancy Regional University Hospital, University of Lorraine, INSERM UMRS 1116 DCAC, Nancy, France.

Introduction: Different surgical approaches are used in aortic surgery. Retroperitoneal approaches can result in abdominal wall weakness and flank bulging. These approaches often require dissection of the anterolateral or anteromedial muscles of the abdominal wall.

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  • A national multicenter study in Saudi Arabia assessed the resistance profiles of a common pathogen causing healthcare-associated infections, using the gold standard broth microdilution method over 2022-2023.
  • The study collected 185 isolates from various infection sites, finding the highest susceptibility to amikacin (76.8%), while notable resistance was observed with meropenem (52%) and colistin (43.8%).
  • The findings revealed a significant level of multidrug-resistance among the isolates, highlighting the need for enhanced antimicrobial stewardship and infection control policies in hospitals to manage and track antibiotic resistance effectively.
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  • Hypertension (HTN) is increasingly becoming a critical health issue in the U.S., with a rise in related cardiovascular deaths, particularly when it becomes refractory, or treatment-resistant.
  • Key risk factors for refractory HTN are linked to demographics (African ancestry, young age, and female gender), health conditions (diabetes, obesity, sleep apnea, kidney disease), and lifestyle choices (smoking).
  • The text also emphasizes three key areas to focus on: understanding the risk factors for refractory hypertension, the potential role of surgical interventions in its management, and the existing referral systems to support patients with refractory HTN.
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  • Peritoneal dialysis (PD) is a less commonly used treatment option compared to hemodialysis (HD) for patients with end-stage kidney disease (ESKD), and understanding patient knowledge about PD is vital for informed decision-making.
  • A study involving 108 HD patients revealed that while many had heard of alternative treatments, only a small percentage understood PD and its benefits; misconceptions and lack of information contributed to its underutilization.
  • Improving education and addressing myths surrounding PD can help promote it as a viable treatment option, ultimately enhancing the quality of life for ESKD patients.
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