Tuning the porosity of triangular supramolecular adsorbents for superior haloalkane isomer separations.

Distillation-free separations of haloalkane isomers represents a persistent challenge for the chemical industry. Several classic molecular sorbents show high selectivity in the context of such separations; however, most suffer from limited tunability or poor stability. Herein, we report the results of a comparative study involving three trianglamine and trianglimine macrocycles as supramolecular adsorbents for the selective separation of halobutane isomers.

Coordination-based self-assembled capsules (SACs) for protein, CRISPR-Cas9, DNA and RNA delivery.

Biologics, such as functional proteins and nucleic acids, have recently dominated the drug market and comprise seven out of the top 10 best-selling drugs. Biologics are usually polar, heat sensitive, membrane impermeable and subject to enzymatic degradation and thus require systemic routes of administration and delivery. Coordination-based delivery vehicles, which include nanosized extended metal-organic frameworks (nMOFs) and discrete coordination cages, have gained a lot of attention because of their remarkable biocompatibility, stability, on-demand biodegradability, high encapsulation efficiency, easy surface modification and moderate synthetic conditions.

Ligand-free gold nanoclusters confined in mesoporous silica nanoparticles for styrene epoxidation.

We present a novel approach to produce gold nanoclusters (Au NCs) in the pores of mesoporous silica nanoparticles (MSNs) by sequential and controlled addition of metal ions and reducing agents. This impregnation technique was followed to confine Au NCs inside the pores of MSNs without adding external ligands or stabilizing agents. TEM images show a uniform distribution of monodisperse NCs with an average size of 1.