4,933 results match your criteria: "King Abdullah International Medical Research center[Affiliation]"

Magnesium sulfate is commonly used intraoperatively to reduce postoperative pain in spinal surgery patients, but its effects when administered postoperatively are not well established. This study specifically aimed to assess the effect of magnesium sulfate on a postoperative basis on the incidence of postoperative pain in lumbar spinal surgery patients. This systematic review focuses on assessing the practicality of postoperative magnesium sulfate in the mitigation of pain after lumbar surgery.

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: The objective of this study was to evaluate the effects of adherence to the ACC/AHA 2018 dyslipidemia guidelines on patient management of lipid-lowering therapy in patients with ischemic heart diseases (IHD) and its correlation with major adverse cardiovascular events (MACEs), including non-fatal MI, stroke, death, hospitalization for revascularization, and peripheral arterial disease. : A multi-center retrospective observational study was conducted in patients with IHD between January 2019 and December 2020, who were followed for two years. The primary objective was to assess statin utilization and adherence to the 2018 ACC/AHA guidelines and the associated influence on MACE outcomes.

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Acute Kidney Injury in Critically Ill Children: Prevalence, Progression, Recovery Mortality, and Impact of Severity.

J Clin Med

January 2025

Department of General Pediatrics, Ministry of the National Guard-Health Affairs, Riyadh P.O. Box 11426, Saudi Arabia.

: Acute kidney injury (AKI) among the pediatric population is considered a risk factor for mortality and morbidities during pediatric intensive care unit (PICU) admission. The association between AKI and increased mortality risk and length of stay (LOS) is still inconclusive. This retrospective cohort study aimed to evaluate the impact of AKI severity upon critical management and clinical parameters with an evaluation of severity progression among AKI patients admitted to the PICU at a tertiary care hospital.

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Coronary and carotid artery diseases are manifestations of a systemic atherosclerotic process, often coexisting in patients affected by both conditions. This association emphasizes the importance of evaluating both coronary and carotid atherosclerosis in high-risk individuals. Ultrasound 2D shear-wave elastography (2D-SWE) has shown promise as a noninvasive technique for assessing carotid plaque stiffness.

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Automated Machine Learning in Dentistry: A Narrative Review of Applications, Challenges, and Future Directions.

Diagnostics (Basel)

January 2025

King Abdullah International Medical Research Center, Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, P.O. Box 3660, Riyadh 11481, Saudi Arabia.

The adoption of automated machine learning (AutoML) in dentistry is transforming clinical practices by enabling clinicians to harness machine learning (ML) models without requiring extensive technical expertise. This narrative review aims to explore the impact of autoML in dental applications. A comprehensive search of PubMed, Scopus, and Google Scholar was conducted without time and language restrictions.

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Background: Psychiatric nurses experience unique emotional and ethical challenges, including moral distress, associative stigma, and compassion fatigue, that can negatively affect their mental health and clinical performance. The complex relationship among these variables has not been clearly defined. Thus, this study aimed to determine the levels of compassion fatigue, associative stigma, and moral distress and to investigate how these factors interact with an emphasis on the role of compassion fatigue in mediating the relationship between associative stigma and moral distress.

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Background: The prevalence of chronic obstructive pulmonary disease (COPD) is increasing in Saudi Arabia, yet there is a lack of studies on the usefulness of routine hematological parameters in predicting mortality.

Objective: To determine hematological parameters that can predict mortality in patients with COPD exacerbation admitted to intensive care units.

Materials And Methods: This multicenter retrospective study included patients with COPD admitted at intensive care units of Ministry of National Guard Health Affairs hospitals in Saudi Arabia between 2016 to 2021.

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Quality of life improvement in children with otitis media with effusion post ventilation tube insertion: A prospective cohort study.

Saudi Med J

February 2025

From the Otorhinolaryngology Head & Neck Surgery Department (Alkhaldi, Alhashem, Al-Saab), King Abdulaziz Medical City-National Guard; from the Department of Research (Alkhaldi, Alhashem, Al-Saab) King Abdullah International Medical Research Center; from the College of Medicine (AlSahli,), King Saud bin Abdulaziz University for Health Sciences; and from the College of Medicine (Al-Ibraheem), Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.

Objectives: To study is to establish the OM-6 scores in Saudi children with OME and subjectively assess the change in QoL following VT insertion. The Otitis Media 6 (OM-6) questionnaire is a widely used measure of the quality of life (QoL) in children with otitis media with effusion (OME). Myringotomy with ventilation tube (VT) insertion is indicated when OME persists with clinically documented hearing impairment.

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Background: The academic performance of students is influenced by several factors, such as academic motivation, self-directed learning, their mindset, and view of themselves.

Aim: This study aimed to assess the impact of academic motivation (AM) on self-esteem (SE) among Saudi Arabian undergraduate dental students.

Methodology: A descriptive cross-sectional study was conducted among undergraduate dental students in Riyadh, Saudi Arabia.

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Background: Although headaches are common, only 3-21% are estimated to be secondary, with their causes ranging from non-alarming to life-threatening conditions.

Objectives: Evaluate the associated factors and predictive warning signs of intracranial pathologies in patients presenting with nontraumatic headaches to the emergency document (ED).

Design: Retrospective chart review.

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Introduction: Research indicates that older hospitalised individuals are more susceptible to hospital adverse events (AEs). Frailty is a syndrome marked by increased vulnerability, sudden and severe health changes and the risk of adverse outcomes. The majority of the available research puts a limited emphasis on those who live with frailty and examines the relationship between age alone and the occurrence of AEs.

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Empowering Women in the Saudi Health Sector: Challenges, Opportunities, and Policy Interventions.

J Epidemiol Glob Health

February 2025

Information Systems Department, College of Computer and Information Sciences, King Saud University, Riyadh, Saudi Arabia.

Introduction: Empowering women in Saudi Arabia has become a critical agenda, reflecting the nation's shifting societal and economic dynamics. This review highlighted recent policy initiatives, societal changes, and institutional reforms aimed at enhancing the role of women in the Saudi health sector.

Methods: This scoping review explored academic literature and government reports related to gender equality and women's empowerment in the Saudi health sector to provide an overview of the advancements made and the challenges that remain.

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Background: The rapid emergence of multidrug-resistant (MDR ) is a major public health and economic burden worldwide. Various resistance mechanisms complicate treatment, leading to increased morbidity and mortality. Despite numerous studies conducted in Gulf Health Council (GHC) countries, the molecular epidemiology of MDR remains not clearly defined.

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Objective: Student self-assessment is a skill that is taught, assessed, and attained in education for lifelong learning. In dental education, developing self-assessment is essential during the early stages of psychomotor learning. This study compared dental students' self-assessments and instructors' assessments in competency examinations and evaluated the progress and potential predictors of self-assessment performance, including achievement level and gender, in a Preclinical Operative Dentistry course.

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Purpose: Dental magnifying loupes (DMLs) allow better visualization of the operative field and operator's seating postures. This study aimed to investigate factors influencing the usage and selection of DMLs among dentists and determine the self-reported musculoskeletal pain and perception regarding DMLs usage.

Methods: A validated self-reported questionnaire of 19 items assessing participant's characteristics and DMLs usage was distributed to individuals who fit the inclusion criteria: practicing general dentists/dental intern and resident/specialized dentist in various dental specialties.

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Objective: This retrospective study aimed to determine the effect of liraglutide on weight and HbA1c levels in patients with type 2 diabetes mellitus (T2DM) in Saudi Arabia. The present investigation was carried out at a medical facility located in the Kingdom of Saudi Arabia.

Materials And Methods: A retrospective analysis was conducted on the clinical records of 290 patients who were diagnosed with T2DM and were above 18 years of age.

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Unlabelled: Hymenoptera stings can lead to a different range of local and systemic reactions. However, rare and unexpected reactions can develop and may be life threatening. In this paper, we present a 29-year-old female who developed anaphylactic shock followed by paraparesis and paraesthesia after a black ant sting.

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The Saudi thoracic society guidelines for vaccinations in adult patients with chronic respiratory diseases.

Ann Thorac Med

October 2024

Professor of Pulmonary Medicine, Department of Medicine, Division of Pulmonary Medicine, King Saud University, Riyadh, Saudi Arabia.

Adult patients with chronic respiratory diseases (CRDs) are considered high risk group who are more likely to experience worse clinical outcomes if they acquire viral or bacterial infections. Vaccination is the best preventive tool to reduce the risk of infection and disease occurrence and to reduce the level of severity of complications associated with the various vaccine-preventable infections. These guidelines were developed by the Saudi Thoracic Society task force to emphasize the critical importance of improving the vaccine coverage rates in adult patients with CRD.

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The pathogenesis of cervical extension of the thymus has been postulated to be incomplete descent of the thymus in the midline of the neck, which is considered normal in children. The thymus normally extends to the neck in approximately two-thirds of children. Ectopic thymus mainly occurs in 1%-13% of the younger population.

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Background The incidence of colorectal cancer (CRC) is increasing nationally, emphasizing the importance of early detection. Late-stage diagnosis, particularly with peritoneal metastasis (PM), is associated with poor outcomes despite advancements in treatment. PM poses a challenge owing to the lack of standardized treatment, although cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) shows promise in improving survival rates.

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Background: Retrograde intrarenal surgery (RIRS) is a preferred treatment for renal stones, yet challenges such as kidney movement due to respiration hinder surgical precision and outcomes. The introduction of flexible and navigable suction ureteral access sheaths (FANS) and novel techniques like gated respiration aim to improve stone-free rates (SFR) and reduce complications. This study evaluates the impact of gated respiration on perioperative outcomes in RIRS with FANS.

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Alveolar socket surface area as a local risk factor for MRONJ development in oncologic patients on polypharmacy.

Clin Oral Investig

February 2025

OMFS-IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, KU Leuven & Department of Oral and Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium.

Objectives: To determine the impact of alveolar socket surface area and number of root extractions for developing medication-related osteonecrosis of the jaw (MRONJ) in polypharmacy patients following multiple tooth extractions.

Materials And Methods: A retrospective sample of 40 patients was recruited, including 20 polypharmacy patients (109 tooth extractions) who developed MRONJ in at least one of the extraction sites, matched with 20 controls (100 tooth extractions). Tooth-specific alveolar socket surface areas were assessed using CBCT scans from the control group to establish reference values for alveolar socket surface areas in polypharmacy patients with MRONJ.

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Objectives: The type of electronic nicotine delivery system (ENDS) used by different age groups may be associated with ENDS and cigarette use behaviours. This study sought to identify differences in the use of ENDS device type based on age and cigarette use status to inform policy about regulating ENDS.

Design: This was a cross-sectional study.

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Introduction: The growing demand for orthodontic treatment in patients irrespective of age highlights the need for effective bonding of brackets to provisional crowns (PCs).

Aims And Objectives: This study evaluates the shear bond strength (SBS) of orthodontic brackets to 3D-printed and milled PC materials, comparing the effects of hydrofluoric acid (HFA) and phosphoric acid (PA) etching.

Materials And Methods: Forty cylinders were fabricated using a 3D printer with hybrid resin, and forty were milled from cross-linked polymethyl methacrylate (PMMA) resin.

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Analyzing the cancer mortality-to-incidence ratios and health expenditures in the aging population: a 20-year comparative study across high-income countries.

Front Aging

January 2025

Department of Cellular Therapy and Cancer Research, King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Jeddah, Saudi Arabia.

Background: The global burden of cancer is expected to increase by 60% over the next two decades, largely due to population aging. The study aims to examine the association between cancer mortality-to-incidence ratios (MIR) with healthcare expenditures (HE), and human development index score for individuals 70 years old or older.

Method: This is an epidemiological study using publicly available data from the Global Burden of Disease (GBD) for six over the years 1990-2019.

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