Obturation quality of bioceramic sealers with different obturation techniques: a micro-CT evaluation.

This micro-computed tomography (micro-CT) analysis in vitro study was designed to compare void volume in root canal fillings performed using the single-cone (SC) technique and the continuous wave condensation (CWC) technique with bioceramic (BC) sealer. Forty human-extracted, single-rooted mandibular premolars were cleaned, shaped, and divided into two groups (n = 20) based on the obturation technique. In the first group, obturation was performed using the CWC technique with TotalFill HiFlow BC sealer.

Exploring Pediatric Sutural Variations with 3D CT Imaging: A Retrospective Study at a Tertiary Hospital.

Background: Sutural anatomy variation has long been a topic of debate among anatomists, paleontologists, and morphologists. While the exact reasons for the prevalence of this variance remains a topic of ongoing discussion, developmental and genetic factors are hypothesized to be the main reasons. Understanding the morphology and occurrence of normal sutural variations in pediatric patients is essential to making the right diagnosis, where a misinterpretation of a sutural bone may lead to an inaccurate assessment, completely misleading the diagnostic process.

Demystifying furan formation in foods: Implications for human health, detection, and control measures: A review.

Furan (C₄H₄O), an unintended hazardous compound, is formed in various thermally processed foods through multiple pathways, raising concerns due to its potential carcinogenicity in humans. The aim of this comprehensive review was to synthesize and evaluate the latest research on furan, from its formation by different precursors to its presence in diverse food matrices, as well as the emerging methods for its detection and mitigation. Emphasizing the toxicity of furan, it explored evidence from in vitro and in vivo studies, including reproductive toxicity, carcinogenic effects, and related biomarkers.

Leveraging fuzzy embedded wavelet neural network with multi-criteria decision-making approach for coronary artery disease prediction using biomedical data.

Coronary artery disease (CAD) is the main cause of death. It is a complex heart disease that is linked with many risk factors and a variety of symptoms. In the past few years, CAD has experienced a remarkable growth.

Knowledge and Practices Regarding Deep Venous Thrombosis (DVT) Prevention Among Nurses in Jeddah, Saudi Arabia.

Background/objectives: Deep venous thrombosis (DVT), the formation of a blood clot within a large vein, is one of the most common problems among hospitalized patients. The annual prevalence of DVT is 48 per 1,000,000. Nurses' knowledge significantly affects compliance with VTE risk assessment and prevention.

Protective Effects of a Sprout Hydroalcoholic Extract on Lipid Homeostasis, Hepatotoxicity, and Nephrotoxicity in Cyclophosphamide-Induced Toxicity in Rats.

possesses a significant concentration of bioactive compounds and has been demonstrated to have a variety of pharmacological properties, although its sprout has not been extensively studied. Thus, the protective effects of sprout hydroalcoholic extract (BNSE) on lipid homeostasis, hepatotoxicity, and nephrotoxicity in cyclophosphamide (CYP)-induced toxicity in rats were examined in this study. Four experimental rat groups ( = 8 for each group) were examined as follows: NR, normal rats that received normal saline by oral gavage daily; CYP, injected with a single dose of CYP at 250 mg kg intraperitoneally (i.

Pesticide exposure promotes disease activity by decreasing lymphoproliferative activity and increasing IL-4 production in systemic sclerosis patients.

Background: One of the common findings in systemic sclerosis (SSc) patients has been long-term exposure to environmental toxins such as pesticides. However, the data available shows an equivocal association between pesticide exposure and autoimmunity in SSc.

Methods: We investigated the levels of organochlorine pesticides (OCPs) in blood of 20 SSc patients and 17 healthy controls, and also studied their effect on T lymphocytes and their functional responses.

Precise vesical wall staging of bladder cancer in the era of precision medicine: has it been fulfilled?

Urinary bladder cancer is a global disease that poses medical and socioeconomic challenges to patients and healthcare systems. Predicting detrusor invasiveness and pathological grade of bladder cancer by the radiologist is imperative for informed decision-making and effective patient-tailored therapy. Cystoscopy and TURBT are the current gold standard for preoperative histologic diagnosis and local pathological staging but are compromised by their intrusiveness, under-sampling, and staging inaccuracies.

Exploring Spine Surgeons' Perspectives on Salah (Islamic prayer) Performance Post-Surgery. Time for consensus?

Background: Post-surgical recovery following spine surgeries poses challenges for Muslim patients wishing to resume Salah (Islamic prayer), which involves physical movements like kneeling and prostration. This study aims to examine spine surgeons' perspectives on the appropriate timing and conditions for resuming Salah after spine surgery without restrictions.

Methods: This cross-sectional survey study included surgeons in Saudi Arabia who perform spine surgeries.

The impact of bilateral transient occlusion of uterine and utero-ovarian arteries on surgical blood loss during laparoscopic myomectomy: A systematic review and meta-analysis of randomized controlled trials.

Background: The primary perioperative concern during laparoscopic myomectomy is the risk of significant intraoperative blood loss, which can lead to hypovolemia, necessitate blood transfusion, and result in postoperative anemia. To address this issue, we conducted a systematic review and meta-analysis to assess the impact of temporarily clamping the uterine and utero-ovarian arteries on operative blood loss during laparoscopic myomectomy.

Methods: We conducted a comprehensive search across various databases to identify eligible clinical trials from inception to May 2024, focusing on randomized controlled trials (RCTs).

Exploring the Influence of Genetic Single-Nucleotide Polymorphism (SNPs) on Endodontic Pathologies: A Comprehensive Review.

A considerable portion of the global population is affected by pulpitis and periapical lesions. While the impact of infections caused by various microbes and host effector molecules in pulpal and periapical diseases is widely recognized, disease susceptibility and progression are also influenced by the dynamic interaction between host genetic factors and environmental influences. Apical periodontitis occurs as an inflammatory response to microorganisms present in the root canals of infected teeth.

Exploring sleep-related disorders in patients with multiple sclerosis: A questionnaire-based approach.

Background: Multiple sclerosis (MS) is considered the most prevalent neurological disorder in young adults with many patients manifesting sleep-related disorders (SRD) due to its pathomechanisms. This is subsequently reflected in patients' quality of life and physical activities.

Material And Methods: This is a cross-sectional study at a tertiary care center.

Intussusception in children with celiac disease.

Celiac disease (CD) is a chronic illness. Blood testing for tissue transglutaminase antibodies is the initial screening test for the diagnosis of CD, and upper gastrointestinal endoscopy and duodenal/jejunal biopsy are used to confirm CD. Intussusception (IS) is the process in which a proximal segment of the bowel invaginates through the lumen of a distal segment.

The effects of the paramedics' field work on their mental status in Jeddah.

Background: Paramedics are continuously exposed to stressful events, making them liable to mental disorders. This study assesses the health of paramedics in Jeddah, focusing on their mental, emotional, and physical well-being.

Methods: This cross-sectional study included fieldwork paramedics in Jeddah through an online survey distributed on social media.

Prevalence of irritable bowel syndrome in endometriosis patients: A cross-sectional study.

Background: Despite its prevalence, limited research has explored the direct correlation between irritable bowel syndrome (IBS) and endometriosis, particularly in regions like Saudi Arabia. This study aimed to bridge this gap by investigating the prevalence of IBS among endometriosis patients and identifying associated risk factors.

Materials And Methods: The study conducted a cross-sectional analysis, it was done at King Abdulaziz University Hospital, Jeddah.

Academic performance of pediatric epileptic patients at King Abdulaziz University Hospital.

Background: Epilepsy is a prevalent neurological condition affecting children worldwide, with a particularly high incidence in Saudi Arabia. Children with epilepsy can experience poor school performance due to cognitive deficits and frequent absences. This study investigates the impact of seizures on school attendance among children with epilepsy.

Factors Affecting Vancomycin Trough Concentration; a Population Pharmacokinetic Model in Non-Critical Care Saudi Patients.

Background And Objective: Vancomycin is commonly prescribed in treatment of methicillin-resistant Staphylococcus aureus infections. While, vancomycins' pharmacokinetic vary among older patients, there is a paucity of data regarding specific characteristics influencing pharmacokinetics in Saudi adult patients. This study aims to establish a population-pharmacokinetic (Pop-PK) model for vancomycin in patients admitted to medical wards, with the focus on identification of patient characteristics influencing vancomycin trough concentrations.

Banning tobacco products sales to adolescents in the Gulf Cooperation Council countries.

Background: Tobacco use poses a challenge to public health in the Gulf Cooperation Council countries. Although restricting access to tobacco can reduce consumption among adolescents, there is limited knowledge of how to implement the tobacco sales ban policy in the sub-region.

Aim: To assess implementation of the ban on tobacco products sales to adolescents in the Gulf Cooperation Council countries as recommended in the WHO Framework Convention on Tobacco Control.

Efficacy and Safety of Prophylactic Agents in Prevention of Retinopathy of Prematurity: A Systematic Review and Meta-analysis of Randomised Controlled rials.

Objective: Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness in preterm infants with low birth weight. The efficacy and safety of prophylactic agents, including vitamin A, propranolol and lipids, in reducing ROP incidence remain unclear. This systematic review and meta-analysis evaluated the effectiveness and safety of these agents in preventing ROP.

Barriers and Facilitators Toward Disaster Knowledge, Skills, and Preparedness among Emergency Medical Services in Saudi Arabia.

Introduction: Disasters pose significant challenges globally, affecting millions of people annually. In Saudi Arabia, floods constitute a prevalent natural disaster, underscoring the necessity for effective disaster preparedness among Emergency Medical Services (EMS) workers. Despite their critical role in disaster response, research on disaster preparedness among EMS workers in Saudi Arabia is limited.

Point shear wave elastography application in assessment pancreas tissue stiffness: A pilot study.

Introduction: Recent advancements in medical imaging, such as point shear wave elastography (pSWE), offer non-invasive methods to assess tissue stiffness and structural changes. This study explores the use of pSWE to evaluate pancreatic stiffness and dimensions in three different pancreas parts.

Methods: This study was conducted at diagnostic radiology department, King Abdulaziz University Hospital, Jeddah, between June 2022 and November,2022.

Characteristics and outcomes of patients with Guillain-Barré syndrome who were admitted to the intensive care unit: a retrospective observational study.

Objective: To evaluate characteristics and outcomes in critically ill patients with Guillain-Barré syndrome (GBS).

Methods: Consecutive adults with GBS who required intensive care unit (ICU) admission at a tertiary-care hospital between 1999 and 2020 were enrolled into this retrospective cohort study. Demographics, clinical data and patient outcomes were compared between patients who did or did not receive mechanical ventilation (MV).

Unusual Presentation of a Pediatric Burkitt's Lymphoma With Infiltration of the Interatrial Septum.

Background: Burkitt's lymphoma (BL) is the most common subtype of non-Hodgkin lymphoma in children, typically presenting with extranodal masses in areas such as the abdomen, face, and neck. Cardiac involvement in BL is extremely rare, especially in pediatric patients, and has significant implications for diagnosis, management, and prognosis.

Case Presentation: A 6-year-old male patient with Burkitt's lymphoma, presenting with an uncommon infiltration of the interatrial septum, is described.