3,677 results match your criteria: "King 's College Hospital NHS Foundation Trust[Affiliation]"
Pediatr Pulmonol
December 2024
Department of Paediatric Respiratory Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Clin Nutr
January 2025
Department of Nutritional Sciences, King's College London, London, UK.
Background And Aims: Infants with biliary atresia experience gastrointestinal malabsorption of long-chain triglycerides and are commonly supplemented with medium-chain triglyceride (MCTs) that can be passively absorbed. The aim was to investigate the association of MCT supplementation with growth, nutritional status and clinical outcomes in infants with biliary atresia.
Methods: Infants who underwent Kasai portoenterostomy and were followed up for at least two years or until death or transplantation were reviewed.
Neurology
January 2025
From the Nuffield Department of Clinical Neurosciences (B.C., A.F., R.G., M.I.S.L., J.P.), Oxford University Hospitals, United Kingdom; Department of Neurology (B.C.), Tongji Hospital of Tongji Medical College, Huazhong University of Science of Technology, Wuhan, China; University Hospitals Sussex National Health Service Foundation Trust (S.A.C.), Brighton; Centre for Preventive Neurology (R.D.), Wolfson Institute of Population Health, Queen Mary University of London; Queen Square Multiple Sclerosis Centre (Y.H.), UCL Institute of Neurology, Faculty of Brain Sciences, University College London; Department of Paediatric Neurology (Y.H.), Great Ormond Street Hospital for Children, London; Department of Neurology (C. Halfpenny), University Hospital Southampton NHS Foundation Trust; Department of Neurology (C. Hemingway), Great Ormond Street Hospital for Children, London and Institute of Neurology; Department of Neurology (J.C.H.), University of Plymouth Faculty of Health and University Hospitals; Department of Ophthalmology (E.O.S.), King's College Hospital NHS Foundation Trust, London; Department of Neurology (W.R.), St George's University Hospitals NHS Foundation Trust, London; Department of Neurology (R.J.M.), Gloucestershire Hospitals National Health Service Foundation Trust; Department of Neurology (V.W.), King's College Hospital NHS Foundation Trust, London; Department of Neurology (V.W.), Guy's and St Thomas' National Health Service Foundation Trust, London; Department of Paediatric Neurology (S.R.), John Radcliffe Hospital, Oxford; and Neurology Department (R.G.), Wexham Park Hospital, Frimley Foundation Health Trust, Slough, United Kingdom.
Neuro Oncol
December 2024
Center for Data Science and AI for Integrated Diagnostics (AI2D), and Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA.
Background: Glioblastoma is the most aggressive adult primary brain cancer, characterized by significant heterogeneity, posing challenges for patient management, treatment planning, and clinical trial stratification.
Methods: We developed a highly reproducible, personalized prognostication and clinical subgrouping system using machine learning (ML) on routine clinical data, MRI, and molecular measures from 2,838 demographically diverse patients across 22 institutions and 3 continents. Patients were stratified into favorable, intermediate, and poor prognostic subgroups (I, II, III) using Kaplan-Meier analysis (Cox proportional model and hazard ratios [HR]).
Med Sci Law
December 2024
Offender Healthcare, St George's, University of London, UK.
JFMS Open Rep
December 2024
IVC Evidensia Small Animal Referral Hospital Hart van Brabant, Waalwijk, The Netherlands.
Case Summary: A 16-year-old spayed female domestic shorthair cat with methimazole-treated hyperthyroidism presented with a chronic progressive history of a stiff gait progressing to recumbency. A neurological examination revealed continuous excessive muscle tone with myokymia, which exacerbated with exercise and persisted during general anaesthesia. An electromyographic study revealed myokymic discharges in all tested muscles, as well as complex repetitive discharges, fibrillation potentials and positive sharp waves.
View Article and Find Full Text PDFEClinicalMedicine
November 2024
Health Service & Population Research Department, Institute of Psychiatry, Psychology, & Neuroscience (IoPPN), King's College London, UK.
Lancet
January 2025
Division of Infection and Immunity, University College London, London, UK; National Institute for Health and Care Research Biomedical Research Centre, University College London Hospitals NHS Foundation Trust, London, UK.
Ann Surg Oncol
December 2024
Department of Hepatopancreatobiliary and Liver Transplant Surgery, Queen Elizabeth Hospital, Birmingham, UK.
J Invest Dermatol
January 2025
King's College Hospital NHS Foundation Trust, London, United Kingdom.
Cureus
December 2024
Medical Education, Great Western Hospitals NHS Foundation Trust, Swindon, GBR.
Cureus
November 2024
Respiratory Medicine, King's College Hospital NHS Foundation Trust, London, GBR.
Smith-Magenis syndrome (SMS) is a genetic disorder characterized by intellectual disability, behavioral challenges, and distinctive physical abnormalities. This case report describes a patient with SMS who presented with pneumonia and was found to have chronic hypercapnic respiratory failure, attributed to kyphoscoliosis and obesity-related conditions such as obesity hypoventilation syndrome and obstructive sleep apnea. Following treatment with non-invasive ventilation (NIV), the patient's baseline oxygen levels improved, and she was discharged with domiciliary NIV and respiratory follow-up.
View Article and Find Full Text PDFPediatr Surg Int
December 2024
Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Purpose: To describe the outcomes of infants with gastroschisis treated with a preformed silo (PFS) and determine whether routinely measured early physiological parameters, sepsis (blood culture positive), gastroschisis complexity or location of birth influenced the length of stay (LOS) and duration of parenteral nutrition (PN).
Methods: Infants cared for in a tertiary surgical neonatal intensive care unit during a 10-year period were identified.
Results: Seventy-seven infants were assessed [median gestational age 36 + 6 (IQR 35 + 3 to 38 + 0)] weeks.
Ann Surg Oncol
December 2024
Department of Hepatopancreatobiliary and Liver Transplant Surgery, Queen Elizabeth Hospital, Birmingham, UK.
BMJ Case Rep
December 2024
Paediatric Haemato-Oncology, Royal Marsden Hospital NHS Trust, London, UK.
Venous thromboembolism (VTE) is a rare event in children and does not usually trigger investigation for malignancy. We report the case of a previously healthy female teenager presenting with unilateral leg swelling. Colour-Doppler ultrasound confirmed deep vein thrombosis (DVT), and the thrombophilia workup was negative.
View Article and Find Full Text PDFResuscitation
December 2024
Essex Cardiothoracic Centre, MSE Trust, Basildon, Essex SS16 5NL, UK; Anglia Ruskin School of Medicine and MTRC, Anglia Ruskin University, Chelmsford, Essex, UK. Electronic address:
Cureus
December 2024
Research, Research Group on Emergency and Disaster Medicine (ReGEDiM), Free University of Brussels, Brussels, BEL.
Education and training in disaster medicine for undergraduate medical students have been advocated for years in several countries. Despite the inclusion of disaster medicine into the medical curriculum being a reality in certain countries, such as the United States and Germany, it is still under scrutiny and yet to be embraced globally. The objective of the study was to examine and map the range of literature and evidence available to support the inclusion of disaster education in the undergraduate medical curriculum and the identification of the related research gaps.
View Article and Find Full Text PDFJ Perinat Med
December 2024
Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Front Neuroendocrinol
November 2024
Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Craniopharyngioma is a benign tumour affecting the hypothalamic and pituitary regions, which are involved in the production and secretion of oxytocin. We conducted a systematic review to assess dysregulation of the oxytocin system in craniopharyngioma and associations with neurobehavioural, eating, and metabolic abnormalities. Eight studies (n = 72 patients) were included.
View Article and Find Full Text PDFBMJ Open Gastroenterol
November 2024
Nuffield Department of Medicine, University of Oxford Translational Gastroenterology Unit, Oxford, UK.
Introduction: The evolving landscape of inflammatory bowel disease (IBD) necessitates refining colonoscopic surveillance guidelines. This study outlines methodology adopted by the British Society of Gastroenterology (BSG) Guideline Development Group (GDG) for updating IBD colorectal surveillance guidelines.
Methods And Analysis: The 'Grading of Recommendations, Assessment, Development and Evaluation' (GRADE) approach, as outlined in the GRADE handbook, was employed.
J Surg Educ
January 2025
MRC Centre for Transplantation, Guy's Hospital, King's College London, London, United Kingdom. Electronic address:
Objectives: The recent shift from traditional surgical teaching to the incorporation of simulation training in plastic surgery has resulted in the development of a variety of simulation models and tools. We aimed to assess the validity and establish the effectiveness of all currently available simulators and tools for plastic surgery.
Design: Systematic review.
Med Teach
November 2024
King's College Hospital NHS Foundation Trust, Denmark Hill, London, UK.
medRxiv
November 2024
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9RT, United Kingdom.
Objective: Novel subcutaneous electroencephalography (sqEEG) systems enable prolonged, near-continuous cerebral monitoring in real-world conditions. Nevertheless, the feasibility, acceptability and overall clinical utility of these systems remains unclear. We report on the longest observational study using ultra long-term sqEEG to date.
View Article and Find Full Text PDFA woman in her 70s presented with features of hyperandrogenism including clitoral enlargement and deepening of her voice. Biochemical investigations revealed raised plasma androgens and urinary androgen metabolites and imaging findings showed a highly F-18 fluorodeoxyglucose (FDG)-PET avid left adrenal tumour initially suspected to be a malignant adrenocortical carcinoma (ACC). She subsequently underwent an uncomplicated laparoscopic adrenalectomy where complete resection of her tumour was achieved.
View Article and Find Full Text PDFRadiography (Lond)
November 2024
Department of Radiography, School of Allied Health Professions, Faculty of Medicine, Health and Social Care, Canterbury Christ Church University, Kent, United Kingdom. Electronic address: