28 results match your criteria: "King's and St Thomas' School of Medical Education[Affiliation]"

Article Synopsis
  • The study aims to assess how genetic factors influence lower urinary tract symptoms (LUTS) in adults by reviewing various research articles.
  • The analysis included 34 studies, focusing on symptoms related to benign prostatic enlargement, urinary incontinence, and other urinary issues, identifying genetic links to conditions like BPE and certain types of UI.
  • The conclusion highlights the complexity of LUTS inheritance and emphasizes the need for further research to better understand these genetic patterns.
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Article Synopsis
  • International guidelines suggest that surgical removal of suspected localized renal cell carcinoma (RCC) is common, but some benign cases are identified post-surgery, highlighting a need for better non-invasive diagnostic tests.
  • A systematic review was conducted on imaging tests' accuracy for T1 renal tumors, analyzing 27 studies involving over 2000 tumors, which highlighted various imaging modalities like CT, MRI, and PET scans.
  • While [Tc]Tc-sestamibi SPECT/CT showed promising sensitivity and specificity, the optimal imaging strategy remains uncertain, calling for further research and standardization of diagnostic criteria across different imaging techniques.
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Introduction: The integration of novel electronic informed consent platforms in healthcare has undergone significant growth over the last decade. Adoption of uniform, accessible, and robust electronic online consenting applications is likely to enhance the informed consent process and improve the patient experience and has the potential to reduce medico-legal ramifications of inadequate consent. A systematic review and meta-analysis was conducted to evaluate the utility of novel electronic means of informed consent in surgical patients and discuss its application to neurosurgical cohorts.

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Background: Disparities in COVID-19 outcomes exist on the basis of ethnicity and comorbidities. Minority ethnic groups in the UK are known to have poorer COVID-19 outcomes, but also an increased prevelance of certain comorbidities associated with severe outcomes. Additionally, despite the prevalence of certain psychiatric disorders there is a lack of research establishing their relationship with COVID-19 outcomes.

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  • About 75% of pancreatic cancer patients experience pain, and over 50% suffer from cachexia, yet there's uncertainty on how to manage these symptoms effectively.
  • The study aims to compare different interventions for managing pain and treating cachexia in patients with unresectable pancreatic cancer through systematic reviews and network meta-analysis, while also developing a clinical care pathway based on patient and healthcare professional input.
  • The methodology includes systematic literature reviews, independent trial screening, risk of bias assessment, and data analysis, culminating in surveys to gather perspectives from patients and caregivers regarding pain and caching management.
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This review aims to provide an update on the role of augmented reality (AR) in surgical training and investigate whether the use of AR improves performance measures compared to traditional approaches in surgical trainees. PUBMED, EMBASE, Google Scholar, Cochrane Library, British Library and Science Direct were searched following PRIMSA guidelines. All English language original studies pertaining to AR in surgical training were eligible for inclusion.

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Article Synopsis
  • Erectile dysfunction (ED) affects 12-19% of men of reproductive age and is more prevalent among those with male infertility, ranging from 6.7 to 61.6%.
  • While ED is a common issue, it only accounts for 0.4-5% of male infertility cases and is often poorly treated, with current therapies providing only temporary relief without addressing the underlying progression of the condition.
  • The article explores the potential of using intracavernosal injections of platelet-rich plasma (PRP) as a regenerative treatment for ED, which may offer a more effective solution compared to current methods.
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Background: Educational videos are a potent resource for the learning of surgical skills among different study cohorts. However, there is limited evidence on the effectiveness of different educational video interventions and their features.

Unlabelled: A systematic search of MEDLINE (via PubMed), Embase (via OVID), Cochrane libraries and Clinicaltrials.

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Introduction: Recent advancements in surgical technology, reduced working hours, and training opportunities exacerbated by the COVID-19 pandemic have led to an increase in simulation-based training. Furthermore, a rise in endovascular procedures has led to a requirement for high-fidelity simulators that offer comprehensive feedback. This review aims to identify vascular surgery simulation models and assess their validity and levels of effectiveness (LoE) for each model in order to successfully implement them into current training curricula.

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Synchronous Parathyroidectomy and Extended Thymectomy in Multiple Endocrine Neoplasia Type 1.

Ann Thorac Surg

August 2022

Department of Otolaryngology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

A 49-year-old man presented with symptoms of hypercalcemia that had been present for 3 months. An initial chest x-ray showed a large anterior mediastinal mass. Subsequent computed tomography also demonstrated a calcified lesion in the uncinate process of the pancreas, and a neck ultrasound showed parathyroid lesions.

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Lung Cancer Surgery in the Early Phase After Acute COVID-19 Pneumonitis.

Ann Thorac Surg

April 2022

Department of Thoracic Surgery, Guy's and St. Thomas' National Health Service Foundation Trust, London, United Kingdom.

A 65-year-old woman was diagnosed with early-stage lung cancer in 2020 and scheduled for robotic assisted-left upper lobectomy. Unfortunately, the patient contracted symptomatic COVID-19, resulting in postponement of lung resection. She was admitted for surgery 6 weeks after the acute infection.

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Visual Impairment, Major Eye Diseases, and Mortality in a Multi-Ethnic Asian Population and a Meta-analysis of Prospective Studies.

Am J Ophthalmol

November 2021

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore. Electronic address:

Purpose: Vision impairment (VI) is associated with poor quality of life and increased risk of falls. Few prospective data are available on Asians. This study investigates the longitudinal impact of VI and the major eye diseases on mortality risk in Asians.

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Background: What subjects UK medical schools teach, what ways they teach subjects, and how much they teach those subjects is unclear. Whether teaching differences matter is a separate, important question. This study provides a detailed picture of timetabled undergraduate teaching activity at 25 UK medical schools, particularly in relation to problem-based learning (PBL).

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Article Synopsis
  • Medical schools in the UK exhibit significant differences in various aspects, including teaching styles, entry criteria, and postgraduate performance, prompting the MedDifs study to explore these variations.
  • The study analyzed aggregated data from 29 medical schools, focusing on 50 different measures such as curricular influences, student satisfaction, and specialty training outcomes.
  • Results indicate that while differences in medical schools are consistent over time, schools using problem-based learning (PBL) tend to have lower postgraduate performance despite higher satisfaction with feedback, suggesting a complex relationship between teaching methods and outcomes.
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Perceptions of risk and influences of choice in pregnant women with obesity. An evidence synthesis of qualitative research.

PLoS One

April 2020

Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.

Background: Between 7-35% of the maternity population are obese in high income countries and 1-40% in lower or middle-income countries. Women with obesity are traditionally limited by the choices available to them during pregnancy and birth because of the higher risk of complications. This evidence synthesis set out to summarise how women with obesity's perceptions of pregnancy and birth risk influence the care choices that they make.

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Current Status of Technical Skills Assessment Tools in Surgery: A Systematic Review.

J Surg Res

February 2020

MRC Centre for Transplantation, Guy's Hospital, King's College London, London, United Kingdom; Department of Urology, King's College Hospital NHS Foundation Trust, London, United Kingdom.

Background: Tools for assessment of technical skills are a crucial part of surgical education. They provide trainees with quantitative feedback highlighting both proficiency and areas for improvement. For this to be relevant to day-to-day practice, the tools used have to be validated and relevant to each surgical situation.

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Compliance of systematic reviews in ophthalmology with the PRISMA statement.

BMC Med Res Methodol

December 2017

Guy's and St. Thomas' NHS Foundation Trust and Balliol College, University of Oxford, Oxford, UK.

Background: Systematic reviews and meta-analyses are becoming increasingly important methods to summarize published research. Studies of ophthalmology may present additional challenges because of their potentially complex study designs. The aim of this study was to evaluate the reporting quality of systematic reviews and meta-analyses on topics in ophthalmology to determine compliance with the PRISMA guidelines.

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Background: Little is known about patients with a first episode of psychosis (FEP) who had first presented to prodromal services with an "at risk mental state" (ARMS) before making the transition to psychosis. We set out to identify the proportion of patients with a FEP who had first presented to prodromal services in the ARMS state, and to compare these FEP patients with FEP patients who did not have prior contact with prodromal services.

Methods: In this study information on 338 patients aged ≤37 years who presented to mental health services between 2010 and 2012 with a FEP was examined.

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Sepsis is the leading cause of child's death, yet it is well known that the rapid initiation of simple, timely interventions reduces morbidity and mortality. This paper shares our findings on the barriers doctors in training have identified to delivering such care. We also share the results of a pilot paediatric intensive care unit outreach teaching programme designed to directly address these highlighted concerns.

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An assessment of the compliance of systematic review articles published in craniofacial surgery with the PRISMA statement guidelines: A systematic review.

J Craniomaxillofac Surg

October 2016

The Academic Surgical Collaborative, UK; Guy's and St. Thomas' NHS Foundation Trust, London, SE1 7EH, UK; Balliol College, University of Oxford, OX1 3BJ, UK. Electronic address:

Context: Systematic review evidence is increasing within craniofacial surgery. Compliance with recognised reporting guidelines for systematic review evidence has not been assessed.

Objective: To assess the compliance of systematic reviews published in craniofacial journals with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting criteria.

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Unlabelled: Cochlear implants for sensorineural deafness in children is one of the most successful neuromodulation techniques known to relieve early chronic neurodisability, improving activity and participation. In 2012 there were 324,000 recipients of cochlear implants globally.

Aim: To compare cochlear implant (CI) neuromodulation with deep brain stimulation (DBS) for dystonia in childhood and explore relations between age and duration of symptoms at implantation and outcome.

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