3 results match your criteria: "Khonkhaen University[Affiliation]"
Protection of human influenza vaccines against a reassortant swine influenza virus of pandemic H1N1 origin using a pig model.
Res Vet Sci
October 2017
Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Henri-Dunant Rd, Bangkok 10330, Thailand; Center of Excellence in Emerging Infectious Diseases in Animals, Chulalongkorn University (CU-EIDAs), Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok 10330, Thailand. Electronic address:
Article Synopsis
- Since the emergence of the H1N1 pandemic in 2009, new reassortant strains of pdmH1N1 have been found in pigs worldwide, raising concerns about their transmission to humans.
- This study evaluated the effectiveness of commercial human subunit vaccines against reassortant swine influenza viruses in pigs, revealing that vaccinated pigs did not show significant clinical improvement against the rH3N2 strain.
- Results indicated that while vaccines generated some protective immune response against other strains (enH1N1, pdmH1N1, rH1N2), they were ineffective against rH3N2, highlighting the need for ongoing surveillance of swine influenza viruses for potential zoonotic risks.
Efficacy of Fostera® PRRS modified live virus (MLV) vaccination strategy against a Thai highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection.
Trop Anim Health Prod
October 2016
Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Recently, the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus (PRRSV) (HP-PRRSV) belonging to lineage 8 causes severe symptom with high morbidity and high mortality rates to the Asian pig industry. A recent study showed that pigs immunized with Fostera® PRRS modified live virus (MLV) of lineage 8 could provide a degree of protection against a Vietnamese HP-PRRSV infection. It should be noted that PRRSV commonly found after weaning causes porcine respiratory disease complex (PRDC).
View Article and Find Full Text PDFCytotoxic activity of lupane-type triterpenes from Glochidion sphaerogynum and Glochidion eriocarpum two of which induce apoptosis.
Planta Med
March 2005
Department of Pharmacology, Faculty of Medicine, Khonkhaen University, Khonkhaen, Thailand.
Six known lupanes lupenone ( 1), 3- epi-lupeol ( 2), glochidone ( 4), glochidonol ( 5), glochidiol ( 6) and lup-20(29)-ene-1beta,3beta-diol ( 7) were isolated from the roots and stem wood of Glochidion eriocarpum and three, 5, 6 and lup-20(29)ene-3alpha,23-diol ( 3), were isolated from the roots and stem wood of Glochidion sphaerogynum. Compounds were identified by (1)H- and (13)C-NMR techniques. Triterpenes 2 - 7 were tested against the growth of three human tumor cell lines, MCF-7, NCI-H-460 and SF-268.
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