110 results match your criteria: "KhonKaen University[Affiliation]"

Objective: This study aims to evaluate the effectiveness of digital health interventions compared to standard care in promoting exclusive breastfeeding (EBF) among postpartum women in low-and middle-income countries (LMICs).

Methods: The PRISMA guidelines of reporting were followed for the searching of four databases and screening following eligibility criteria: articles presenting digital health interventions, conducted as randomized control trials (RCTs), quasi-experimental, or mixed-method studies, reporting on EBF duration and early initiation of breastfeeding, and published in the English language were included.

Results: Of 1595 articles screened, only 10 published between 2013 and 2023 met the criteria.

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is a significant zoonotic pathogen, capable of causing severe illnesses such as septicemia and meningitis in both swine and humans. Its transmission through pork consumption necessitates effective food safety measures. Lime juice, known for its antimicrobial properties, presents a potential alternative to reduce contamination in pork products.

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Article Synopsis
  • Cardiovascular disease, particularly ST elevation myocardial infarction (STEMI), remains a leading cause of death globally, with different outcomes observed in young adults compared to older patients.
  • A study analyzed data from 5,479 STEMI patients to identify factors and short-term outcomes, revealing young patients (under 40) were predominantly male, had higher smoking rates, and greater instances of obesity and family history of coronary artery disease (CAD).
  • Despite experiencing higher rates of procedural failure and complications, the in-hospital death rate for young patients was lower compared to older counterparts, indicating different mortality trends among age groups.
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The effects of physical exercise on fitness and emotion in Chinese preschoolers.

BMC Public Health

September 2024

Key Laboratory of Child Cognition &Behavior Development of Hainan Province, Haikou, 571100, China.

Article Synopsis
  • The study highlights the rising issue of overweight and obesity in children under five and the decline in their physical activity, emphasizing the impact on cognitive performance.
  • It investigated the effects of three physical education programs on the fitness and emotional skills of 239 preschoolers in Haikou, China, over a ten-week period.
  • Results showed significant improvements in physical fitness for those in the "Hello Sunshine" and ordinary physical education groups compared to a free play group, and both intervention groups reported lower anxiety levels post-program.
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Revisiting morphology of xiphoid process of the sternum in human: a comprehensive anatomical study.

Surg Radiol Anat

October 2024

Department of Neurosurgery, Clinical Neuroscience Research Center, Tulane University School of Medicine, 131 S. Robertson St. Suite 1300, New Orleans, LA, 70112, USA.

Article Synopsis
  • The xiphoid process (XP) in humans, considered an anatomical variant, was studied to better understand its morphology and cartilage presence.
  • A study using twenty embalmed cadaveric sterna revealed that 85% of XPs contained cartilage, classified into four types based on bone and cartilage proportions.
  • The findings suggest that previous research may have misjudged the XP's size and emphasizes the importance of recognizing xiphoidal cartilage as a normal anatomical feature.
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Severe hyperlactatemia in the emergency department: clinical characteristics, etiology and mortality.

BMC Emerg Med

August 2024

Department of Emergency Medicine, Faculty of Medicine, Thanon Mittraphap, KhonKaen University, Amphoe Mueang, Khon Kaen, 40002, Thailand.

Background: Severe hyperlactatemia (lactate level ≥ 10 mmol/L) is associated with high mortality rates in critically ill patients. However, there is limited data on emergency department (ED) patients. We aimed to investigate the clinical characteristics, etiology and outcomes of patients with severe hyperlactatemia in the ED setting.

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Lettuce seed pelleting with sp. 31-12: plant growth promotion under laboratory and greenhouse conditions.

Can J Microbiol

December 2024

Department of Plant Science and Agricultural Resources, Faculty of Agriculture, KhonKaen University, Khon Kaen 40002, Thailand.

Plant growth promotion by sp. 31-12 incorporated into a lettuce seed pelleting matrix was studied. We examined (1) the effect of five rhizosphere derived bacterial strains on green oak lettuce ( L.

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Individual cytotoxicity of three major type A trichothecene, T-2, HT-2, and diacetoxyscirpenol in human Jurkat T cells.

Toxicon

May 2024

Interdisciplinary Graduate Program in Genetic Engineering, Graduate School, Kasetsart University, Bangkok, 10900, Thailand; Department of Pharmacology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, 10900, Thailand. Electronic address:

Mycotoxins are toxic, fungal secondary metabolites that contaminate agricultural commodities, food, and feed. Among them, T-2, HT-2, and diacetoxyscirpenol (DAS; the major type A trichothecene) are primarily produced from Fusarium species. These mycotoxins exert numerous toxicological effects in animals and humans, such as dermatotoxicity, haematotoxicity, hepatotoxicity, nephrotoxicity, neurotoxicity, and immunotoxicity.

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Background: Inflammation caused by infection increases the risk of cholangitis, cholecystitis, and leads to bile duct cancer (cholangiocarcinoma or CCA). However, only certain infected individuals are susceptible to CCA, suggesting the involvement of host factors in cancer development. In addition, there are reports indicating differences in the locations of CCA.

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Article Synopsis
  • The CRUSADE score is used to assess in-hospital bleeding risks for patients with NSTEMI going through PCI, particularly in Asian populations like those in Thailand.
  • A study was conducted using data from the Thai PCI registry to validate and simplify the CRUSADE score, concluding that both the original and a revised version accurately predicted major bleeding outcomes.
  • The final simplified version of the CRUSADE score, which only incorporates four key factors, also demonstrated strong predictive ability, indicating its effectiveness in the Thai NSTEMI patient population.
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Detection of high-risk HPV 16 genotypes in cervical cancers using isothermal DNA amplification with electrochemical genosensor.

Talanta

March 2024

Biosensors Laboratory, Department of Biomedical Engineering, Faculty of Engineering, Mahidol University, Nakhon Pathom, 73170, Thailand. Electronic address:

Cervical cancer emerges as the third most prevalent types of malignancy among women on a global scale. Cervical cancer is significantly associated with the persistent infection of human papillomavirus (HPV) type 16. The process of diagnosing is crucial in order to prevent the progression of a condition into a malignant state.

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This research assesses the flood vulnerability of Thailand's flood-prone province of Pathum Thani using a comprehensive vulnerability assessment framework. The assessment framework incorporates three key components: exposure, sensitivity, and adaptive capacity, consisting of 10, 12 and 11 flood vulnerability indicators, respectively. The flood vulnerability components and the flood vulnerability indicators are statistically validated by confirmatory factor analysis to determine the factor loadings and reliability of the components and indicators.

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Background: Bleeding following percutaneous coronary intervention (PCI) has important prognostic implications. The Academic Research Consortium (ARC) have identified a set of clinical criteria to standardize the definition of a high bleeding risk (HBR). Current study sought to externally validate the ARC definition for HBR patients in a contemporary real-world cohort.

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The host-targeting compound peruvoside has a broad-spectrum antiviral activity against positive-sense RNA viruses.

Acta Pharm Sin B

May 2023

Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore 117597, Singapore.

Positive-sense RNA viruses modify intracellular calcium stores, endoplasmic reticulum and Golgi apparatus (Golgi) to generate membranous replication organelles known as viral factories. Viral factories provide a conducive and substantial enclave for essential virus replication concentrating necessary cellular factors and viral proteins in proximity. Here, we identified the vital role of a broad-spectrum antiviral, peruvoside in limiting the formation of viral factories.

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Chronic respiratory diseases (CRDs) constitute 4% of the global disease burden and cause 4 million deaths annually. This cross-sectional study used QGIS and GeoDa to explore the spatial pattern and heterogeneity of CRDs morbidity and spatial autocorrelation between socio-demographic factors and CRDs in Thailand from 2016 to 2019. We found an annual, positive, spatial autocorrelation (Moran's I >0.

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This study aimed to investigate the potential of using field two-spotted cricket as the main protein source in fish feed for striped snakehead () juveniles. A 10-week feeding effect on growth performance, feed utilization, digestibility of major nutrients, including amino acids, and physiological outputs of nitrogen and phosphorus were determined. A total of 225 juvenile fish (Initial weight, 15.

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Effect of doctor allocation policies on the equitable distribution of doctors in Thailand.

Hum Resour Health

January 2023

International Health Policy Program, Ministry of Public Health, Tiwanon Road, Muang, 11000, Nothaburi, Thailand.

Background: Equitable geographic distribution of doctors is crucial for the provision of an accessible and efficient health service system. This study aimed to assess the effects of doctor allocation by the Thai Ministry of Public Health (MoPH) in relation to equity distribution.

Methods: This descriptive study compared secondary data on the number of doctors, gross provincial products (GPP), and populations of 76 Thai provinces for the years 2017 and 2021.

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Article Synopsis
  • The study focused on validating the ACUITY/HORIZON risk score for predicting bleeding in patients undergoing PCI (percutaneous coronary intervention) in a large Thai registry of ACS (acute coronary syndrome) patients.
  • Results showed that both original and updated models overestimated bleeding risk, but the updated model improved prediction accuracy by incorporating factors like congestive heart failure, prior vascular disease, and body mass index.
  • The updated models exhibited good calibration and discriminatory capacity for predicting bleeding, demonstrating their effectiveness for real-world ACS patients regardless of the bleeding definitions used.
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Background: Percutaneous coronary intervention (PCI) practice and outcomes vary substantially in different parts of the world. The contemporary data of PCI in Asia are limited and only available from developed Asian countries.

Objectives: To explore the pattern of practice and results of PCI procedures in Thailand as well as a temporal change of PCI practice over time compared with the registry from other countries.

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Background: Liver fluke caused by Opisthorchis viverrini is a serious health problem in the northeastern region of Thailand. It is associated with endemic cholangiocarcinoma (CCA) in this region. This study was performed to develop a school-based health literacy model for liver fluke prevention and control using participatory action research.

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Factors Influencing Demand for Medical Cannabis Use among Cancer Patients in the North of Thailand.

Asian Pac J Cancer Prev

January 2022

Department of Public Health Administration, Health Promotion, and Nutrition, Faculty of Public Health, KhonKaen University, KhonKaen, Thailand.

Objective: Cancer treatments often cause side effects. Cannabis is a plant that has been studied and used to treat and relieve side effects from modern medicine. Medical cannabis (MC) was legalized in Thailand in 2019 with limited research on demand for its use.

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Pulmonary hypertension is a significant complication in thalassemia patients. Recent studies showed that inhaled nebulized nitrite could rapidly decrease pulmonary artery pressure. We conducted a multicenter, randomized, double-blind, placebo-controlled trial in thalassemia patients with symptomatic pulmonary hypertension diagnosed by right heart catheterization.

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Human strongyloidiasis is one of the neglected tropical diseases caused by infection with soil-transmitted helminth Strongyloides stercoralis. Conventional stool examination, a method commonly used for diagnosis of S. stercoralis, has low sensitivity, especially in the case of light infections.

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A DFT calculation on nonenzymatic degradation of isoaspartic residue.

J Mol Model

September 2021

Supramolecular Chemistry Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Pathumwan, Bangkok, 10320, Thailand.

βAsp is an isomer of Asp that can be formed by either deamidation of Asn or isomerization of Asp and known as biological clock. The presence of βAsp affects the proteolytic stability of the protein. Formation of the isomerized Asp plays a diverse and crucial role in aging, cancer, autoimmune, neurodegenerative, and other diseases.

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