6,459 results match your criteria: "Khalifa University Khalifa University of Science & Technology[Affiliation]"

Probiotic and Rice-Derived Compound Combination Mitigates Colitis Severity.

Pharmaceuticals (Basel)

October 2024

Biological Science Department, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.

Article Synopsis
  • This study explored how () and Hasawi rice protein lysate (HPL) can help reduce colitis, an inflammatory condition of the colon, induced in mice by DSS.
  • Researchers evaluated various factors such as disease activity index (DAI), gut permeability, and antioxidant enzyme activity to determine the effectiveness of the treatments.
  • Results showed that the combination of both treatments significantly improved symptoms, reduced oxidative stress, and lower pro-inflammatory markers, indicating that () with HPL could be a promising approach for managing colitis.
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The presence of -, , gene family has been reported in many important plants, playing roles in various aspects of plant biology but little has been uncovered in soybeans. Soybean is one of the major plants providing nutrition for humans and livestock globally. In this study, we overexpressed a novel gene () in and conducted bioinformatic analyses, evaluated the T2 transgenic line in an open field, and applied major stressors along with the growth promoter GA to investigate the potential functions of the gene.

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Metallic nanoparticles have found wide applications due to their unique physical and chemical properties. Green biosynthesis using plants, microbes, and plant/microbial extracts provides an environmentally friendly approach for nanoparticle synthesis. This review discusses the mechanisms and factors governing the biosynthesis of metallic nanoparticles such as silver, gold, and zinc using various plant extracts and microorganisms, including bacteria, fungi, and algae.

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Background: Loquat fruit is consumed for its flavorful taste and a rich array of health-promoting compounds like phenolics, flavonoids, and carotenoids. This study aimed at the biochemical characterization of fresh juice from the Moroccan variety of loquat and evaluating its effects on lipid homeostasis and liver steatosis in hyperlipidemic mice.

Methods: The biochemical characterization followed AOAC methods.

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Alzheimer's disease treatment landscape: current therapies and emerging mechanism-targeted approaches.

Neural Regen Res

November 2024

Department of Anesthesiology, Pharmacology and Therapeutics, and Djavad Mowafaghian Center for Brain Health, University of British Columbia, Vancouver, BC, Canada.

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The naked-eye detection of hazardous pollutants through simple and cost-effective techniques is of great interest to the scientific community and related stakeholders in analytical science. The present study emphases the development of a stimuli-responsive probe by encountering sophisticated techniques for the detection of environmental pollutants. Herein, highly swellable and fluorescent-WTR-CDs-loaded HB-Alg/Gel@WTR-CDs was fabricated through a simple extrusion dripping method.

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Mpox, formerly known as Monkeypox, is a viral zoonotic disease endemic to Central and West Africa that has posed significant public health challenges since its identification in 1970. Despite decades of experience in managing outbreaks, the 2022-2024 Mpox outbreaks exposed substantial gaps in global preparedness and response, leading the World Health Organization (WHO) to declare a Public Health Emergency of International Concern (PHEIC) in 2022. The resurgence of cases in Europe in 2022 and the more recent emergence of the virulent clade Ⅰb in the Democratic Republic of the Congo (DRC) in 2024 have highlighted a critical need for improved proactive and response strategies to curb the epidemic.

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Global burden of disease attributable to metabolic risk factors in adolescents and young adults aged 15-39, 1990-2021.

Clin Nutr

December 2024

MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China. Electronic address:

Background: Metabolic risk factors are a significant cause of global burden among adolescents and young adults, but there is a lack of attention to the burden attributable to these metabolic risk factors globally.

Aims: This study aims to provide comprehensive estimates of five important metabolic risk factors and the attributable disease burden in people aged 15-39 years from 1990 to 2021, based on the Global Burden of Disease Study (GBD) database.

Methods: Global total deaths and disability-adjusted life years (DALYs) were used to describe the burden attributable to five common metabolic risk factors, including high fasting plasma glucose (FPG), high low-density lipoprotein cholesterol (LDL-C), high systolic blood pressure (SBP), high body mass index (BMI), and kidney dysfunction, in adolescents and young adults.

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Three distinct ternary complexes (TC-M1, TC-M2, and TC-M3) based on lactoferrin (LF), (-)-epigallocatechin-3-gallate (EGCG), and α-lactalbumin (ALA) were prepared by varying the assembly sequence and EGCG concentrations (ranging from 0 to 2.0 mM). Structural characterization was performed using various spectroscopic techniques, while the assembly mechanisms were investigated through ITC and molecular docking.

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This scoping review explores mobile health (mHealth) technologies and their features affecting medication adherence in cancer patients. Among 11 selected studies, predominantly from the USA, mHealth tools, particularly smartphone apps, were examined for their features in managing cancer patient's medication adherence. The studies highlighted the importance of adherence in continuous cancer therapy, with mHealth tools offering reminders and interactive features, that aim to enhance patient engagement.

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We aimed to assess perceptions about interprofessional collaboration (IPC) of healthcare professionals working in an acute medical unit (AMU) in an internal medicine department in the United Arab Emirates. The AMU provides care during the initial 24 to 72 hours of admission and emphasizes interprofessional collaboration. Using the Assessment of Interprofessional Team Collaboration Scale II, the study measured partnership, cooperation, and coordination among team members.

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Infections attributable to respiratory syncytial virus (RSV) are a major cause of hospitalization among young children worldwide. Despite substantial clinical and economic burden, real-world data associated with RSV infections in the United Arab Emirates (UAE) are limited. This study aimed to assess among children (<18 years) diagnosed with RSV the epidemiology, seasonality, comorbidities, treatment patterns, length of hospital stay, healthcare resource utilization (HCRU), and costs associated with pediatric infection in Dubai, UAE.

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Purpose: It remains unclear if fluid pressures used during cataract surgeries contribute to iatrogenic corneal endothelial cell (CEC) loss.

Methods: A custom experimental platform was used to pressurize the anterior chamber of explanted porcine eyes to surgical fluid pressures of 60 mm Hg or 400 mm Hg for 5 minutes or 60 mm Hg for 45 minutes (n = 8 or 9 per group). The corneal endothelia were stained with a unique combination of nucleic acid viability dyes and were imaged using fluorescence microscopy without removing the cornea from the globe.

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Correction: Second-shell modulation on porphyrin-like Pt single atom catalysts for boosting oxygen reduction reaction.

Chem Sci

November 2024

Shenzhen Key Laboratory of Micro/Nano-Porous Functional Materials (SKLPM), SUSTech-Kyoto University Advanced Energy Materials Joint Innovation Laboratory (SKAEM-JIL), Department of Chemistry and Department of Materials Science and Engineering, Southern University of Science and Technology (SUSTech) Shenzhen 518055 China

Article Synopsis
  • This text is a correction to a previously published article identified by the DOI: 10.1039/D4SC03369H.
  • The correction likely addresses errors or inaccuracies found in the original article.
  • The purpose is to ensure that the scientific record is accurate and reflects the correct information. *
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The research on aerial manipulation systems has been increased rapidly in recent years. These systems are very attractive for a wide range of applications due to their unique features. However, dynamics, control and manipulation tasks of such systems are quite challenging because they are naturally unstable, have very fast dynamics, have strong nonlinearities, are very susceptible to parameters variations due to carrying a payload besides the external disturbances, and have complex inverse kinematics.

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Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold.

Eur J Med Chem

January 2025

Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2.3, 66123, Saarbrücken, Germany. Electronic address:

Article Synopsis
  • CK2 is an important enzyme involved in cell growth and survival, making it a potential target for cancer treatments, but many existing inhibitors are not selective enough.
  • Researchers discovered a new compound, a dihydropyrido-thieno[2,3-d]pyrimidine derivative, which showed strong inhibitory activity against CK2α and was notable for its unique chemical structure.
  • The most effective compound, 10b, had an IC value of 36.7 nM and demonstrated good selectivity and cellular activity against certain cancer cell lines, outperforming existing inhibitors in terms of inducing cell death.
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Survival rates with favorable neurological outcomes after in-hospital and out-of-hospital cardiac arrest: A prospective cohort study.

Intensive Crit Care Nurs

November 2024

Medical Intensive Care Unit, Hamad General Hospital, Doha, Qatar; Department of Medicine, Weill Cornell Medical College, Doha, Qatar. Electronic address:

Objectives: To evaluate the survival rates with favorable neurological outcomes among patients who experienced in-hospital cardiac arrest (IHCA) and out-of-hospital cardiac arrest (OHCA).

Design: This prospective cohort study assessed 554 adult patients with IHCA or OHCA referred to Hamad General Hospital, Qatar, between February 2015 and November 2021. Neurologic outcomes were measured using the Cerebral Performance Category (CPC) score.

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This research reports a continuous output ionic thermoelectric (i-TE) system based on MXene/PVA (polyvinyl alcohol) hydrogel, by utilizing thermo-diffusion of Cu and Cl ions and the redox reaction involving Cu/Cu at the electrode interfaces. The thermopower of the i-TE system can be independently tuned to a value of -3.13 mVK by adjusting the ion diffusivity via MXene (TiCT).

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Pediatric double-seropositive anti-glomerular basement membrane antibody disease: A case report and literature review.

Clin Nephrol Case Stud

November 2024

Department of Pediatrics, Cheikh Khalifa International University Hospital, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.

Introduction: Glomerular basement membrane (GBM) disease is a severe and exceedingly rare disorder characterized by the presence of circulating antibodies targeting the non-collagen NC1 domain of the α3 chain of collagen type IV in glomerular and alveolar basement membranes. It typically presents as rapidly progressive glomerulonephritis (RPGN), often accompanied by pulmonary hemorrhage. The occurrence of double-seropositivity for anti-GBM antibody and anti-neutrophil cytoplasmic antibody (ANCA), primarily with myeloperoxidase specificity (MPO-ANCA), is particularly uncommon in pediatric cases.

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Article Synopsis
  • The COVID-19 pandemic has had serious effects on maternal and neonatal health, prompting a systematic review to assess how it influences respiratory distress syndrome (RDS) in newborns from infected mothers.
  • The review analyzed 22 studies and found that 11.5% of newborns from COVID-19-positive mothers experienced RDS, with a risk ratio of 2.69 indicating a significantly higher risk compared to newborns from non-infected mothers.
  • The findings stress the importance of closely monitoring and managing pregnant women with COVID-19 to reduce potential health issues in their newborns.
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The increasing global energy demand and environmental pollution necessitate the development of alternative, sustainable energy sources. Hydrogen production through electrochemical methods offers a carbon-free energy solution. In this study, we have designed novel boron nitride analogues (BNyne) and investigated their stability and electronic properties.

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The brain must guide immediate responses to beneficial and harmful stimuli while simultaneously writing memories for future reference. While both immediate actions and reinforcement learning are instructed by dopamine, how dopaminergic systems maintain coherence between these 2 reward functions is unknown. Through optogenetic activation experiments, we showed that the dopamine neurons that inform olfactory memory in Drosophila have a distinct, parallel function driving attraction and aversion (valence).

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Landau-Level Quantization and Band Splitting of FeSe Monolayers Revealed by Scanning Tunneling Spectroscopy.

Nano Lett

December 2024

State Key Laboratory of Low-Dimensional Quantum Physics, Department of Physics, Tsinghua University, Beijing 100084, China.

Two-dimensional (2D) superconductors that reside on substrates must be influenced by Rashba spin-orbit coupling (SOC). The intriguing effect of Rashba-type SOCs on iron-based superconductors (IBSs) has remained largely a mystery. In this work, we unveil modified Landau-level spectroscopy and the intricate band splitting of FeSe monolayers through the precision of scanning tunneling spectroscopy, which unequivocally demonstrates the presence of Rashba SOC.

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Article Synopsis
  • The study aimed to investigate the prevalence of genetic variants associated with high-risk ovarian cancer in Somali patients treated at a single institution from 2015 to 2022.
  • Out of eight patients studied, 60% showed a significant BRIP1 splice site mutation, while one had a BRCA2 pathogenic variant, indicating a concerning genetic trend in this population.
  • The findings highlight the need for improved genetic screening and address healthcare disparities, emphasizing the importance of community-based research to enhance cancer care for Somali women.
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