27 results match your criteria: "Key-Disciplines Laboratory Clinical-Medicine[Affiliation]"

[Expression of Piwil2 and its relationship with tumor invasion and metastasis in papillary thyroid carcinoma].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

March 2011

Department of Thyroid Surgery, The First Affiliated Hospital of Zhengzhou University, Key-Disciplines Laboratory Clinical Medicine, Zhengzhou 450052, China.

Objective: To study the expressions of Piwil2 protein and mRNA in papillary thyroid carcinoma (PTC) and the relationship between Piwil2 and the invasion and metastasis of PTC.

Methods: Immunohistochemistry and in situ hybridization were used to detect the expression of Piwil2 protein and mRNA in 60 cases of PTC with the matched adjacent non-cancerous epithelium (NCE).

Results: The positive rates of Piwil2 protein expression in PTC and NCE were 88.

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Inhibitory effect of S-adenosylmethionine on the growth of human gastric cancer cells in vivo and in vitro.

Chin J Cancer

August 2010

Department of Gastroenterology, the First Affiliated Hospital of Zhengzhou University, Key-Disciplines Laboratory Clinical-Medicine, Zhengzhou, Henan 450052, P. R. China.

Background And Objective: S-adenosylmethionine (SAM), the most important methyl donor in human body, is generally used to treat cholestasis in clinic. In recent years, SAM has been found to have inhibitory effects on breast cancer, liver cancer and colon carcinoma. This study was to investigate the inhibitory effects of SAM on human gastric cancer cells in vivo and in vitro, and the antitumor mechanisms.

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