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Hedgehog signalling is downregulated in celiac disease.
Can J Gastroenterol
January 2013
Key Laboratory of Developmental Diseases in Childhoold (Chongqing Medical University), Ministry of Education, China.
Background: Celiac disease (CD) is a common autoimmune disorder of the small intestine that occurs in genetically predisposed individuals. Animal studies have suggested that the hedgehog (Hh) signalling pathway is involved in gut inflammation, injury and repair.
Objective: To examine the expression of components of the Hh signalling pathway in CD.