Monocular patching affects inattention but not perseveration in spatial neglect.

Monocular patching might improve perceptual-attentional, not motor-intentional deficits in a patient with chronic post-stroke left spatial neglect. Performing a line-cancellation task, his omission errors were associated with a perceptual-attentional 'where' deficit, while perseverative errors were associated with 'aiming' motor-intentional bias. Contralesional patching had no effect on the omissions (p = .

Cognitive reserve protects against cognitive dysfunction in multiple sclerosis.

Cognitive reserve theory helps to explain the neuropsychological expression of neurologic disease (e.g., Alzheimer's disease; Stern, 2006).

Cognition in multiple sclerosis: a review of neuropsychological and fMRI research.

Multiple Sclerosis (MS) is a disease of the central nervous system affecting millions of people worldwide. In addition to the disabling physical symptoms of MS, roughly 65% of individuals with MS also experience significant cognitive dysfunction, especially in the domains of learning/memory, processing speed (PS) and working memory (WM). The purpose of this review is to examine major topics in research on cognitive dysfunction, as well as review recent functional magnetic resonance imaging (fMRI) studies focusing on cognitive dysfunction in MS.

Best research evidence for physical medicine and rehabilitation.

Evidence-based medicine is a strong movement in this century, and randomized clinical trials continue to be the best level of evidence for establishing cause-effect relationships between treatment interventions and outcomes. The field of physical medicine and rehabilitation has many excellent research questions on the effects of treatment but seems to rely mostly on weak observational methods (eg, chart review, case series, and single-group designs) for answers. This paper highlights 3 basic and relatively simple principles of good experimental design: control, randomization, and replication that were developed by R.

Rose-colored answers: neuropsychological deficits and patient-reported outcomes after stroke.

Patient-reported, subjective outcomes are promoted as a standard for ethical, valid studies in many neurological disorders. Such outcomes are considered potentially more sensitive and specific to important therapeutic effects, and may be more linked to disability and disease-related life losses than conventional assessments of impairment (e.g.

Monocular patching may induce ipsilateral "where" spatial bias.

Spatial bias is an asymmetry of perception and/or representation of spatial information - "where" bias -, or of spatially directed actions - "aiming" bias. A monocular patch may induce contralateral "where" spatial bias (the Sprague effect [Sprague, J. M.