Correction: Association between type 2 diabetes and branched chain amino acids (BCAA); a case-control study.

[This corrects the article DOI: 10.1007/s40200-023-01247-9.].

Expanding the genotypic and phenotypic spectrum of EAST/SeSAME syndrome: identification of a novel homozygous mutation (c.194 G > A) in KCNJ10 gene.

Introduction: EAST/SeSAME syndrome is an ultra-rare disease characterized by seizures, epilepsy, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance and arises due to deleterious variants disrupting the function of the KCNJ10 gene. In this study, we investigated the clinical symptoms and genetic cause of the disease in a 10-year-old Iranian girl who presented with neurological, hearing, and renal problems.

Methods: Magnetic resonance imaging (MRI), electroencephalography (EEG), and laboratory tests were performed to evaluate the clinical characteristics of the proband.

Estimating the impact of the first 2 years of the COVID-19 pandemic on tuberculosis diagnosis and treatment outcomes in Southeastern City in Iran: an interrupted time series analysis of the preceding 10 years of ecological data.

Background: With shared modes of transmission and clinical symptoms the convergence of COVID-19 and tuberculosis (TB) might lead to reduced diagnosis and detection of TB, which is challenging for healthcare systems already strained by the pandemic's reach.

Methods: This ecological study investigated the impact of the COVID-19 pandemic on TB surveillance over the first 2 years of the pandemic (March 2020 to February 2022) in southeastern Iran. Interrupted Time Series (ITS) analysis with the quasi-Poisson regression models was used to estimate the relative risk (RR) of TB diagnosis and treatment outcome counts, stratified by gender, case definition, involvement type, and treatment outcomes.

Practical application of melatonin for pancreas disorders: protective roles against inflammation, malignancy, and dysfunctions.

Melatonin, a hormone primarily produced by the pineal gland, exhibits a range of physiological functions that extend beyond its well-known role in regulating circadian rhythms. This hormone influences energy metabolism, modulates insulin sensitivity, and plays a significant role in controlling sleep patterns and food intake. Notably, melatonin is also synthesized in various peripheral organs, including the gastrointestinal system and pancreas, suggesting its function as a local hormone.

A Closer Look at the Avian Influenza Virus H7N9: A Calm before the Storm?

The avian influenza A (H7N9) virus, which circulates in wild birds and poultry, has been a major concern for public health since it was first discovered in China in 2013 due to its demonstrated ability to infect humans, causing severe respiratory illness with high mortality rates. According to the World Health Organization (WHO), a total of 1568 human infections with 616 fatal cases caused by novel H7N9 viruses have been reported in China from early 2013 to January 2024. This manuscript provides a comprehensive review of the virology, evolutionary patterns, and pandemic potential of H7N9.

Effectiveness of computer-based telerehabilitation software (RehaCom) compared to other treatments for patients with cognitive impairments: A systematic review.

Background: The rehabilitation process for cognitive disorders is long and complex, which can lead to reduced rehabilitation outcomes and reduced quality improvement. Thus, there is a need to use new methods to boost conventional rehabilitation (e.g.

CoWO/Reduced Graphene Oxide Nanocomposite-Modified Screen-Printed Carbon Electrode for Enhanced Voltammetric Determination of 2,4-Dichlorophenol in Water Samples.

Water pollution with phenolic compounds is a serious environmental issue that can pose a major threat to the water sources. This pollution can come from various agricultural and industrial activities. Phenolic compounds can have detrimental effects on both human health and the environment.

Musculoskeletal disorders among bank workers: a systematic review and meta-analysis.

Purpose: Bank employees are among the workers who are at a high risk of suffering from musculoskeletal disorders (MSDs) due to inactivity and prolonged sitting as well as static and poor postures. This study was conducted with the aim of systematic review and meta-analysis of the prevalence of MSDs among bank employees.

Materials And Methods: This review followed the PRISMA guidelines and its protocol is registered in PROSPERO with the code CRD42024509728.

In vitro and in silico studies of a Zn(II) complex as a potential therapeutic agent for breast cancer.

Breast cancer (BC) is one of the most life-threatening diseases of women's health worldwide. This work was conducted to assess the anti-BC potency of a new Zn(II)-based complex. The Zn(II) complex coordinated to dimethoxy-substituted bipyridine was synthesized and its molecular structure was elucidated as [Zn(bpy)](clo) (bpy-Zn) by single-crystal X-ray diffraction, bpy represents 4,4'-dimethoxy-2,2'-bipyridine.

Effect of Air Pollutants and Environmental Noise on the Childhood Asthma Prevalence in Tehran, Iran.

The purpose of this study is to investigate the effect of air pollutants and noise on the prevalence of childhood asthma in Tehran, Iran. The standardized questionnaire was completed by one of the parents of children aged 6-7 years or by adolescents aged 13-14 years. The asthma prevalence in ages 6-7 and 13-14 was found to be 8.

Visit-to-visit variability of blood pressure and risk of diabetic retinopathy: a systematic review and meta-analysis.

Background: Diabetes mellitus (DM), a worldwide disease affecting more than 400 million people, is associated with high blood pressure (BP). In addition to macrovascular complications, high BP in DM patients is potentially linked to microvascular complications. More than 70% of DM patients have retinopathy.

Machine learning in obsessive-compulsive disorder medications.

Obsessive-compulsive disorder (OCD) is the fourth most common psychiatric disorder with a significant morbidity rate. Despite various treatment modalities and medications, some patients show no definitive response. The aim of this study is to classify the medications of OCD with machine learning (ML) methods and to compare the classification performances of the decision tree (DT), chi-square automatic interaction detection (CHAID) algorithm, and linear model in ML methods.

Moderate-intensity training can ameliorate the process of cardiac apoptosis induced by lithium drug consumption in male Wistar rats.

Background And Objective: Lithium medication, given its significant role in the treatment or reduction of psychiatric disorders, may exert adverse effects on cardiac tissue. Therefore, this study aimed to investigate the effects of different exercise training intensities on the process of cardiac apoptosis and serum levels of cardiac troponin I (cTnI) resulting from lithium administration in male Wistar rats.

Methodology: In the present experimental study, 35 male Wistar rats were randomly divided into five groups (n=7); Control (CTL), Lithium (Li), High-Intensity training + lithium (HIT-Li), Moderate-Intensity training + lithium (MIT-Li), and Low-Intensity training + lithium (LIT-Li).

A assessment of the effects of parental age on the development of autism in children: a systematic review and a meta-analysis.

Objective: There has been conflicting evidence in earlier research on the association between parental age and autism risk. To clarify this association, we conducted a comprehensive meta-analysis of observational studies. The primary objective of this study was to determine the association between parents' age and the risk of autism in the offspring.

Availability and affordability of selected medicines in the Islamic Republic of Iran.

Background: There is a standard methodology for measuring and evaluating the availability and affordability of selected medicines in the healthcare system, especially in low- and middle-income countries.

Aim: To investigate availability, affordability and accessibility of medicines in the Islamic Republic of Iran in 2021 and compare the results with those from 2019.

Methods: This descriptive cross-sectional study investigated the availability and affordability of 60 selected medicines in Islamic Republic of Iran.

Low level laser therapy and rheumatoid arthritis: a systematic review and meta-analysis study.

This systematic review and meta-analysis aimed to evaluate the efficacy of Low-Level Laser Therapy (LLLT) in the treatment of Rheumatoid Arthritis (RA), focusing on its effects on pain relief, grip strength, and morning stiffness. A comprehensive search was conducted across PubMed, Scopus, and Web of Science, yielding 3,111 articles. After eliminating duplicates and screening titles and abstracts, 94 full-text articles were assessed, and 23 studies met the eligibility criteria for inclusion in the systematic review.

Living on the slum areas in the shadow of drought: a qualitative analysis of lived experience of migrant households facing drought in Southeast of Iran.

Background: Drought is one of the most destructive and complex natural hazards, with direct and indirect effects, especially economic effects, on society and households. It affects the well-being and life satisfaction of households. It is important to understand the effects of drought at the micro level, such as households, by examining different attitudes, perceptions, and experiences of drought and its impacts.

The ecological impact of the COVID-19 pandemic on crime trends in Kerman Province of Iran.

The COVID-19 pandemic has significantly impacted crime rates in Kerman province, Iran, revealing divergent patterns compared to global trends. This ecological study utilized the Poisson regression model and interrupted time-series Poisson regression model to analyze data collected from the Iranian Legal Medicine Organization (ILMO) database and the Kerman Criminal Investigation Department of Police database, focusing on theft, conflicts, and homicide rates in this region. Our findings indicate that in 2020, the incidence rate ratio of conflicts increased compared to previous years.

The impact of anesthesia instruments and drugs on the occurrence of vocal cord injury, systematic review and meta-analysis.

Objective: This study extensively examined common complications related to anesthesia drugs and equipment on vocal cords. It also delved into factors such as smoking, anesthesia duration and anesthesia induction methods. Overall, the research aimed to pinpoint influential factors for creating a general anesthesia protocol with minimal post-operative complications.

Intracranial hypertension and papilledema secondary to an unruptured arteriovenous malformation: Review of the literature.

Arteriovenous malformations (AVMs) are abnormal connections of arteries and veins without intermediate capillary components. As such, AVMs can remain asymptomatic or have a variety of clinical presentations ranging from mild headaches to severe symptoms like seizures, hemorrhage, and subsequent coma. Papilledema and increased intracranial pressure without hydrocephalus or hemorrhage are rare forms of presentations of cerebral AVM.

Fabrication of the carbon paste electrode modified with Trametes versicolor laccase immobilized on carboxyl functionalized multi-walled carbon nanotubes and its application for measurement of dopamine.

Dopamine (DA) shows numerous roles in a wide range of physiological and pathological processes. In this study, an immobilized laccase-derived biosensor was developed for DA detection. The carboxyl functionalized multi-walled carbon nanotubes (MWCNTs-COOH) was applied for immobilization of laccase from Trametes versicolor (TvLac).