455 results match your criteria: "Keratosis Pilaris"
Dermoscopic Features of Pili Annulati: Features of PA.
Skin Res Technol
October 2024
Tianjin Children's Hospital/Children's Hospital, Tianjin University, Tianjin, China.
Folliculocentric tinea versicolor: a case report.
J Med Case Rep
September 2024
Department of Dermatology, Wuhan No. 1 Hospital, Wuhan, 430022, China.
Article Synopsis
- Tinea versicolor is a common skin condition, and this report focuses on a unique follicular form observed in a patient with a past of keratosis pilaris.
- A 46-year-old Asian woman presented with light brown patches on her trunk and axillae, which were diagnosed as folliculocentric tinea versicolor through clinical examination and microscopic analysis.
- The case suggests a potential link between previous keratosis pilaris and the development of follicular tinea versicolor, although the exact causes of this form remain uncertain.
The development and validation of an investigator global assessment score for keratosis pilaris.
J Eur Acad Dermatol Venereol
September 2024
Faculty of Medicine & Health, University of New South Wales, Sydney, Australia.
Keratosis Follicularis Spinulosa Decalvans Associated With Woolly Hair: A Case Report.
Cureus
July 2024
Dermatology, King Abdulaziz Hospital, Makkah, SAU.
Article Synopsis
- Keratosis follicularis spinulosa decalvans X-linked (KFSDX) is a rare skin disorder affecting hair and skin, characterized by abnormal hair and skin lesions.
- A 14-year-old boy showed symptoms from birth, including scarring alopecia and follicular papules, with a family history showing no similar conditions.
- After skin biopsy and differential diagnosis, he was diagnosed with KFSDX but did not return for follow-up treatment.
Efficacy and safety of non-cross-linked hyaluronic acid compound in the treatment of keratosis pilaris: A split-body randomized clinical trial.
J Cosmet Dermatol
December 2024
Department of Plastic and Reconstructive Surgery, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Article Synopsis
- Keratosis pilaris (KP) is a common and harmless skin condition causing small bumps and redness, affecting people's appearance and mental health.
- A clinical trial tested a non-cross-linked hyaluronic acid (HA) treatment for KP, where injections were given in four sessions over 24 weeks, and both doctors and patients evaluated the results.
- Results showed significant improvements in skin roughness and redness for treated areas, with many patients reporting sustained benefits, indicating the HA treatment is effective and safe for managing KP.
A nonsense variant in KRT31 is associated with autosomal dominant monilethrix.
Br J Dermatol
November 2024
Institute of Human Genetics, University of Bonn, Medical Faculty and University Hospital Bonn, Bonn, Germany.
Article Synopsis
- Monilethrix is a rare genetic hair disorder characterized by fragile hair with a beaded structure and potential keratosis pilaris or nail issues, linked to mutations in specific genes (KRT81, KRT83, KRT86 for dominant forms; DSG4 for recessive).
- This study aimed to uncover new genetic mutations in families with unexplained cases of autosomal-dominant monilethrix and to explore how these variants disrupt cell function.
- Through exome sequencing, researchers identified a significant mutation (c.1081G>T) in the KRT31 gene that affects keratin production, resulting in altered protein structure and function, confirmed through various laboratory techniques.
A Case of Noonan Syndrome and Kyrle's Disease: Coincidence or Causality?
Acta Dermatovenerol Croat
March 2024
Marco Brusasco, MD, University of Parma, Via Gramsci 14, Parma, Italy;
Article Synopsis
- A 39-year-old woman with Noonan Syndrome and a RAF1 mutation presented with itchy lesions on her limbs that developed two months prior, characterized by multiple dome-shaped papules.
- Blood tests showed no abnormalities, but a skin biopsy revealed features consistent with Kyrle's disease, a type of perforating dermatosis.
- The patient was treated with narrowband UVB phototherapy, resulting in complete resolution of symptoms despite leaving residual atrophic scars.
Efficacy of fractional radiofrequency in the treatment of erythematous capillary rosacea: A split-face study.
J Cosmet Dermatol
September 2024
Department of Dermatology, The First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, China.
Article Synopsis
- ! The study aimed to evaluate the effectiveness and safety of fractional radiofrequency (FRF) treatment for erythematotelangiectatic rosacea in 20 patients, focusing on changes before and after treatment. * ! Results showed significant reductions in redness and porphyrin levels on the treated side compared to the untreated side, indicating positive treatment effects, while pain scores averaged around 3.67 out of 10. * ! Adverse effects were recorded, but the study highlighted overall patient satisfaction and noticeable skin improvements, including reduced pore size and lighter skin tone on the treated side. *
Nilotinib Induced Keratosis Pilaris in a Female with Chronic Myeloid Leukemia.
Dermatol Pract Concept
April 2024
Department of Dermatology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Navigating Diagnostic Uncertainty: Frontal Fibrosing Alopecia Versus Keratosis Pilaris Atrophicans Faciei With Genetic Testing Insights.
Cureus
April 2024
Ronald O. Perelman Department of Dermatology,, New York University (NYU) Grossman School of Medicine, New York, USA.
Article Synopsis
- - Keratosis pilaris atrophicans faciei (KPAF) and frontal fibrosing alopecia (FFA) are similar skin conditions that make diagnosis tricky for dermatologists, often leading to overlapping treatment methods.
- - Genetic testing holds promise for more precise diagnoses and personalized treatment plans for these conditions, but it hasn't been widely applied yet.
- - The case study of a 36-year-old male shows that despite negative genetic testing results, exploring genetic factors can still improve diagnosis and treatment efficacy for similar dermatological issues.
Keratosis Pilaris-Like Reaction Associated With Chromatin Remodeling Complex Inhibition in Uveal Melanoma.
JAMA Dermatol
June 2024
Department of Pathology, Section of Dermatopathology, The University of Texas MD Anderson Cancer Center, Houston.
Keratosis pilaris treatment paradigms: assessing effectiveness across modalities.
Clin Exp Dermatol
September 2024
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia.
Article Synopsis
- * A thorough literature search identified 52 articles that provided concrete outcome data on the effectiveness of different treatments, with laser and light therapies showing the most significant results, particularly the Nd:YAG laser.
- * Despite some treatments showing improvements, the inconsistency in results highlights the need for a standardized scoring system to better compare effectiveness, indicating that more research is crucial for establishing reliable KP treatment guidelines.
A Case of Noonan Syndrome and Kyrle Disease: Casualty or Causality?
Acta Dermatovenerol Croat
December 2023
Marco Brusasco, MD, Dermatology Section Department of Medicine and Surgery, University of Parma, Via Gramsci, 14, 43126 Parma, Italy;
Article Synopsis
- A 39-year-old woman with Noonan Syndrome and RAF1 mutation presented with itchy skin lesions on her limbs, which were diagnosed as Kyrle disease (KD) after a detailed examination.
- KD is characterized by dome-shaped papules with a central keratotic plug and is often linked to systemic conditions such as chronic renal failure and diabetes, although this patient did not have these issues.
- Treatment involved narrowband UVB phototherapy, leading to complete resolution of symptoms, which highlights the importance of managing underlying health conditions in skin diseases like KD.
Dermatologic manifestations in pediatric patients with inflammatory bowel disease.
Pediatr Dermatol
March 2024
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
Article Synopsis
- The study investigates dermatologic conditions in children with inflammatory bowel disease (IBD), focusing on their prevalence and relationship with disease severity.
- Researchers reviewed data from 528 children and adolescents with IBD, identifying high rates of skin issues, particularly infections and common conditions like acne and eczema.
- Findings revealed that children with Crohn's disease (CD) are more likely to have certain skin issues while more severe IBD cases are linked to specific dermatological problems like perianal disease and psoriasis.
Keratosis Punctata of Palmar Creases.
J Cutan Med Surg
May 2024
Gupta Hospital, Dhamtari, Chhattisgarh, India.
Article Synopsis
- * A clinical study involving 30 participants tested a moisturizing cream with 20% urea for four weeks, showing significant improvements in skin smoothness and texture at both one and four weeks.
- * Most participants expressed satisfaction with the cream, noting enhanced skin feel, increased confidence, and reduced embarrassment about their condition, without any major side effects reported.
Keratosis Pilaris-like Eruption during Treatment of Chronic Myeloid Leukemia with Tyrosine Kinase Inhibitors: Literature Review and Report of a Case Related to Imatinib.
J Clin Med
December 2023
Section of Dermatology and Venereology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.
Article Synopsis
- The introduction of tyrosine kinase inhibitors (TKIs) has significantly improved treatment for chronic myeloid leukemia (CML), particularly for blocking the BCR-ABL enzyme.
- Adverse cutaneous reactions (ACRs), especially a rash resembling keratosis pilaris, commonly occur with drugs like nilotinib and dasatinib, but are rare with imatinib.
- This report details a case of an elderly patient who developed a KP-like rash after one month of imatinib treatment, along with a discussion of similar reactions and the potential biological mechanisms behind them.
Clinicopathologic and trichoscopic features of keratosis follicularis spinulosa decalvans: A case series study.
J Dermatol
February 2024
Department of Dermatopathology, Hospital for Skin Diseases and Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College Nanjing, Jiangsu, China.
Article Synopsis
- Keratosis follicularis spinulosa decalvans (KFSD) is a rare hereditary disorder marked by excessive skin cell production in hair follicles, light sensitivity, and hair loss, with challenging diagnosis due to diverse clinical presentations.
- A study evaluated eight patients from seven families, where alopecia typically began around 21.25 years old, mainly affecting scalp hair with scarring and inflammation, alongside hyperkeratosis of vellus hairs in all cases.
- Histological examination showed significant changes in hair follicles, including inflammation and follicular obstruction, while trichoscopic examination revealed specific features like scaling and tufted hairs, indicating that abnormalities in hair follicles are key to understanding the disease.
Keratosis Pilaris Atrophicans Faciei: A Case Treated with 585 nm Diode Laser, a Novel Fractional Solid-State.
Clin Cosmet Investig Dermatol
December 2023
Department of Dermatology, Izmir City Hospital, İzmir, Turkey.
Article Synopsis
- Keratosis pilaris atrophicans faciei (KPAF) is a rare genetic skin condition related to the follicular type of keratosis pilaris.
- Treatment options have evolved to include light and laser therapies, with pulsed dye laser (PDL) being particularly effective for KPAF.
- This text details a unique case where a patient with KPAF was successfully treated using a 585 nm diode laser, marking the first documented use of this specific laser technology for this condition.
Keratosis Pilaris: Treatment Practices of Board-Certified Dermatologists.
J Drugs Dermatol
October 2023
Article Synopsis
- Keratosis pilaris (KP) is a chronic skin condition marked by rough bumps on areas like the arms and legs, and topical therapies such as lactic acid are commonly used to treat it.
- A survey of dermatologists revealed that lactic acid is the most popular first-line treatment, while laser therapy is rarely used due to insurance and equipment issues.
- The study also found that many patients experience recurrence of KP lesions shortly after stopping treatments, highlighting the condition’s difficulty to manage.
Combining antimicrobial substances for Campylobacter post harvest mitigation on chicken breast fillet and chicken skin - any synergistic effects?
J Appl Microbiol
September 2023
Institute for Food Quality and Food Safety, University of Veterinary Medicine Hannover, Foundation, Hannover 30173, Germany.
Article Synopsis
- * Two organic acids, peroxyacetic acid and lactic acid, along with two plant extracts, carvacrol and resveratrol, were tested for their ability to inhibit growth of Campylobacter species.
- * Results showed that peroxyacetic acid was particularly effective in dramatically reducing Campylobacter on chicken skin, proving to be a promising method for food safety without affecting taste.
Keratosis pilaris-like eruptions in a child following COVID-19 vaccination.
Int J Dermatol
November 2023
Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taipei, Keelung, Taoyuan, Taiwan.
A Review of the Scoring and Assessment of Keratosis Pilaris.
Skin Appendage Disord
August 2023
Department of Dermatology, St George Hospital, Sydney, NSW, Australia.
Article Synopsis
- - Disease severity assessment tools are crucial for evaluating skin conditions, but there is no validated tool specifically for keratosis pilaris (KP), a common but benign follicular disorder.
- - Various unvalidated scoring methods, like investigator global assessment (IGA) scores and quartile grading systems, have been used in clinical trials, leading to inconsistency in results.
- - Establishing a standardized and validated scoring system for KP is essential to improve clinical trials and enhance the understanding of this condition.
Generalized keratosis pilaris induced by testosterone injections in a patient with CHARGE syndrome.
Dermatol Reports
June 2023
Dermatology and Dermatologic Surgery Department, Prince Sultan Military Medical City, Riyadh.
Article Synopsis
- - Keratosis pilaris (KP) is a skin condition marked by small, rough bumps around hair follicles, often accompanied by redness, and is quite common, particularly in kids and adolescents.
- - It can affect up to 50% of healthy children and is even more prevalent in children with atopic dermatitis, generally becoming less common as people age.
- - The report discusses a unique case involving a 13-year-old boy with CHARGE syndrome who developed widespread KP following testosterone injections, marking this as the first documented instance of this occurrence.
Pediatric obesity and skin disease: cutaneous findings and associated quality-of-life impairments in 103 children and adolescents with obesity.
Endocr Connect
August 2023
Department of Pediatric Dermatology and Allergology, Children's Hospital Auf der Bult, Hannover, Germany.
Article Synopsis
- The study investigates the relationship between skin conditions and various health parameters in children and adolescents with obesity, focusing on how these skin issues affect their quality of life (QoL).
- A total of 103 participants (average age 11.6 years) showed a high prevalence of skin problems like striae distensae and acne vulgaris, which were linked to higher body mass index (BMI) and insulin resistance as measured by the HOMA score.
- Findings suggest that skin lesions in obese youth are common and may indicate underlying health issues, highlighting the need for regular skin assessments and collaborative healthcare strategies to enhance overall well-being.