2,820 results match your criteria: "Keratoacanthoma"
Cost-efficiency of excision and non-excision-based keratoacanthoma treatment modalities.
Int J Dermatol
November 2024
Department of Dermatology, Henry Ford Health, Detroit, MI, USA.
Article Synopsis
- * Early detection of multiple KAs is important for diagnosing underlying causes and preventing related health issues, which can improve patient quality of life and provide family counseling.
- * Current research is limited and often based on small studies, so this work aims to review existing knowledge on multiple KAs, especially linked to genetic syndromes, and to propose a diagnostic algorithm for better clinical guidance.
Ultrasound Characteristics of Keratoacanthoma: Differentiation From Well-Differentiated Cutaneous Squamous Cell Carcinoma.
J Ultrasound Med
November 2024
Department of Pathology, Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China.
Article Synopsis
Topical 5-fluorouracil 4% resolves anti-PD-1 induced keratoacanthomas in enteropathy-associated T-cell lymphoma allogeneic transplant patient.
Int J Dermatol
November 2024
Bone Marrow Transplantation Unit, Department of Internal Medicine, School of Medicine, University Hospital of Patras, Patras, Greece.
Skin as a Reflection of Gut Health: An Overview of Dermatological Manifestations in Primary Neoplastic and Autoimmune Gastrointestinal Disorders.
Cureus
October 2024
Internal Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Gastrointestinal (GI) diseases can present with several extraintestinal manifestations, and cutaneous signs and symptoms are most frequent. Although conventionally GI and skin are considered two entirely separate organ systems, they are closely correlated in origin. An increasing amount of data highlights the complex relationship between GI and dermatological conditions.
View Article and Find Full Text PDFConcurrent Eruptive Melanocytic Nevi and Multiple Keratoacanthomas Induced by Encorafenib.
Cureus
September 2024
Oncology, Biokliniki Athinon, Athens, GRC.
Article Synopsis
- - A case study discusses a 64-year-old male with metastatic colorectal cancer who developed severe itching and new skin lesions after treatment with encorafenib and panitumumab, medications targeting cancer pathways.
- - The patient showed a mix of skin lesions, including benign moles and keratoacanthomas, with further evaluation confirming a link between the skin reactions and the use of encorafenib, as validated by the Naranjo scale.
- - Stopping the medications led to significant improvement in skin lesions, highlighting the importance of ongoing skin assessments for patients on BRAF inhibitors to manage side effects effectively.
Keratoacanthoma versus Squamous-Cell Carcinoma: Histopathological Features and Molecular Markers.
Dermatopathology (Basel)
October 2024
Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
Considerable controversy exists within the field of dermatopathology in differentiating keratoacanthoma (KA) from squamous-cell carcinoma (SCC). KAs are rapidly growing, benign squamous tumors that are typically well differentiated. This controversy stems from the diverging perspectives on the management, classification, and diagnosis of each entity.
View Article and Find Full Text PDFA Case Report of a Keratoacanthoma of the Lip in a Pediatric Patient and Narrative Review.
Ear Nose Throat J
October 2024
Department of Stomatology, New Century Women's and Children's Hospital, Qingdao, Shandong, China.
Article Synopsis
Article Synopsis
- The study investigates the role of Demodex mites in the development of eyelid papillomas, focusing on how their presence may influence the tumor's histomorphological characteristics.
- Histomorphological examinations revealed demodectic infection indicators, such as cystic formations and remnants of the mite, in nearly half of the analyzed cases, found within tumor tissues and surrounding structures.
- The findings suggest that these cavity defects created by mite activity may serve as indicators of Demodex infestation, with implications for understanding their impact on various eyelid tumors, including keratoacanthomas and senile keratosis.
Diagnosing Common Benign Skin Tumors.
Am Fam Physician
October 2024
Prisma Health and the University of South Carolina School of Medicine, Greenville.
Article Synopsis
- Distinguishing between benign and potentially malignant skin tumors is crucial in family medicine, and many benign tumors can be diagnosed based on their history, appearance, and growth patterns.
- Procedures like biopsy or excision may be necessary if there's uncertainty about a diagnosis or if the lesion changes rapidly.
- Treatment options vary based on the type of lesion and patient preference, with methods like excision, laser therapy, and cryotherapy commonly used; special considerations are needed for patients with darker skin to minimize risks like hypopigmentation.
Epidemiologic trends in cutaneous squamous cell carcinoma from 2011 to 2021 at All Africa Leprosy, Tuberculosis, and Rehabilitation Training Center (ALERT) in Addis Ababa, Ethiopia.
JAAD Int
December 2024
Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia.
Article Synopsis
- Cutaneous squamous cell carcinoma (cSCC) is the most prevalent form of skin cancer in dark-skinned populations, but research on its prevalence and treatment is mainly focused on white populations, particularly neglecting black Africans like Ethiopians.
- * The study aimed to evaluate the prevalence and risk factors of cSCC among patients at a rehabilitation center in Addis Ababa, Ethiopia, using a combination of literature review and retrospective data analysis from 2011 to 2021.
- * Results showed that cSCC accounted for 3.8% of total samples, with a majority of cases appearing in females and patients often presenting symptoms after more than a year; key findings included a high proportion of well-differentiated tumors
Clinical and Dermoscopic Patterns of Basal Cell Carcinoma and Its Mimickers in Skin of Color: A Practical Summary.
Medicina (Kaunas)
August 2024
Institute of Dermatology, Department of Medical Area, University of Udine, 33100 Udine, Italy.
Article Synopsis
- Diagnosing basal cell carcinoma (BCC) in individuals with darker skin tones (dark phototypes IV-VI) is difficult due to varied presentations and fewer identifiable clues; dermoscopy can aid in identifying BCC in these patients.
- This review provides a comparison of BCC's clinical and dermoscopic patterns in people of color to those in lighter-skinned individuals, identifying common mimickers like squamous cell carcinoma and melanoma.
- Key dermoscopic features of BCC in darker skin include blue, black, and gray dots, with arborizing vessels being the primary indicator, while unique conditions in darker skin such as dermatosis papulosa nigra are also considered in differential diagnosis.
Rotation flap: Advantages in skin lesions of the dorsum of the hand.
Hand Surg Rehabil
October 2024
Departamento de Anatomía Patológica, Facultad de Medicina, Universidad de Chile, Chile.
Delayed onset eruptive keratoacanthomas following immune checkpoint inhibitor therapy.
Int J Dermatol
September 2024
Department of Dermatology, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Corrigendum: Differential Immunoexpression of Inhibitory Immune Checkpoint Molecules and Clinicopathological Correlates in Keratoacanthoma, Primary Cutaneous Squamous Cell Carcinoma and Metastases.
Acta Derm Venereol
September 2024
Department of Dermatology, University Hospital Heidelberg, Im Neuenheimer Feld 440, DE-69120 Heidelberg, Germany.
Article Synopsis
- This Corrigendum addresses errors found in the original article linked in the text.
- It aims to clarify and correct specific information presented in the article.
- Readers are encouraged to refer to the corrigendum for accurate and updated details regarding the original research findings.
MULTIPLE KERATINOCYTIC CANCERS AFTER INTAKE OF ANTIHYPERTENSIVES (LISINOPRIL/BISOPROLOL/HCT) AND ANTIARRHYTMICS (PROPAFENONE): THE IMPORTANT NEW LINKS TO THE NITROSO-CONTAMINATION AND THE METABOLIC REPROGRAMMING OF THE FUTURE CANCER CELL.
Georgian Med News
June 2024
3Department of Dermatology and Venereology, Military Medical Academy, Sofia, Bulgaria.
Article Synopsis
- The mechanisms behind the development of skin tumors are still not fully understood, particularly regarding the roles of photosensitivity and phototoxicity.
- Recent studies have linked specific nitrosamines, contaminants in common pharmaceuticals, to gene and phototoxicity in humans, raising concerns about their potential carcinogenic effects.
- Long-term use of contaminated medications may contribute to skin cancer risk by interfering with tumor suppressor genes and activating oncogenes, affecting overall cancer development.
Generalized Eruptive Keratoacanthoma (GEKA) after Pfizer mRNABNT162b2 (Comirnaty) COVID-19 Vaccination Successfully Treated with Cemiplimab.
Viruses
August 2024
Dermatology Unit "Daniele Innocenzi", "A. Fiorini" Hospital, via Firenze, 1, 04019 Terracina, Italy.
Article Synopsis
- * A 64-year-old man with a history of hypertension and diabetes developed multiple keratoacanthomas two weeks after his second booster dose, prompting diagnosis through physical and histopathological examinations.
- * The patient's condition improved significantly with treatment using cemiplimab, suggesting a possible immune-mediated reaction from the vaccine, but further studies are necessary to assess treatment safety and effectiveness.
Conjunctival keratoacanthoma: a clinical and histopathological case series.
Can J Ophthalmol
August 2024
Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States.
Article Synopsis
- The study focuses on conjunctival keratoacanthomas, rare eye lesions, by analyzing patient data from 2005 to 2023, including clinical characteristics and treatment outcomes.
- Out of nine patients identified, most were middle-aged Hispanic males, with lesions commonly found in the right eye and on the temporal conjunctiva, showing rapid growth and specific imaging features.
- Histopathological examination revealed distinct features such as keratin-filled lesions, and after surgical removal, most patients (except two lost to follow-up) showed no recurrence over an average follow-up period.
Advantages of Nail Surgical Procedures Using a 3D Biomodel.
Skin Appendage Disord
August 2024
Universidade Federal Fluminense de Niterói, Rio de Janeiro, Brazil.
Article Synopsis
- * In three cases of nail tumors, doctors used 3D models to create special tools and plan surgeries, making them more effective and less invasive.
- * Overall, using 3D models can improve surgery quality and safety, plus help educate future doctors.
[Translated article] Dermoscopy of Squamous Cell Carcinoma: From Actinic Keratosis to Invasive Forms.
Actas Dermosifiliogr
October 2024
Servicio de Dermatología, Hospital de Sant Pau i Santa Tecla, Tarragona, Spain.
Article Synopsis
- The dermoscopy of squamous cell carcinoma (SCC) helps differentiate between types based on keratin, vascular, and pigment features.
- Non-pigmented actinic keratoses have a "strawberry pattern," while pigmented actinic keratosis shows similarities to lentigo maligna but can be distinguished by specific signs like pigmented scales and erythema.
- Dermoscopy is crucial for early detection of invasive SCC, with its presentation varying by tumor differentiation—keratin features in well-differentiated tumors and atypical vascular patterns in poorly differentiated ones.
Intralesional Methotrexate Injection for the Treatment of Epithelial Crateriform Tumor.
Ann Dermatol
August 2024
Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
Background: Intralesional methotrexate injection (IL-MTX) is an appropriate strategy for treating epithelial crateriform tumors (ECTs) when surgical excision can result in functional or cosmetic defects; however, not all ECTs are responsive to this treatment.
Objective: This study aimed to evaluate the effectiveness of IL-MTX for ECTs and to determine the differences in clinical response according to the pathological features.
Methods: The medical records of patients treated with IL-MTX for their ECTs were retrospectively reviewed.
Diffuse eruptive squamous atypia, also known as eruptive keratoacanthoma: Unique case presentation.
JAAD Case Rep
July 2024
Department of Dermatology, University of Wisconsin, Madison, Wisconsin.
A case report of squamous cell carcinoma mimicking interdigital intertrigo.
Oxf Med Case Reports
July 2024
Department of Dermatology and Venereology, Mohammed VI University Hospital, M3MF+GCG, La Nouvelle Ville Ibn Batouta, Tangier, Morocco.
Article Synopsis
- Squamous cell carcinoma (SCC) is a common type of skin cancer that can affect the nails, exemplified by a 60-year-old male patient who developed a painful ulcer in his foot due to a prior misdiagnosis of a fungal infection.
- Dermatological examination showed characteristics of SCC, and although the initial biopsy indicated keratoacanthoma, it did not reveal malignant features, leading to the eventual identification of moderately differentiated SCC in a follow-up biopsy.
- Successful surgical resection was performed to treat the SCC, highlighting the importance of accurate pathology understanding and biopsy techniques in preventing progression of this form of skin cancer.
Esthetic and medical tattooing: Part I: Tattooing techniques, implications, and adverse effects in healthy populations and special groups.
J Am Acad Dermatol
July 2024
Arena Dermatology, Herzliya, Israel. Electronic address:
Article Synopsis
- - Tattooing has a long and diverse history, holding cultural, cosmetic, and medical importance, which makes understanding its complications crucial as the popularity of tattoos rises.
- - Common issues with tattoos include hypersensitivity reactions and infections, often linked to poor hygiene practices during the tattooing process or while healing.
- - This article provides a comprehensive overview of tattoos, covering their history, cultural relevance, potential complications, and implications for cancer diagnosis, helping both potential clients and medical professionals navigate the risks involved.
Skin cancers arising within tattoos: A systematic review.
JAAD Int
September 2024
Duke University School of Medicine, Durham, North Carolina.
Article Synopsis
- Tattooing has become increasingly popular, but it is associated with certain skin lesions, including malignant tumors.
- A review of cases revealed 160 instances of skin cancers linked to tattoos, showing a rise in reported occurrences, particularly with tumors arising from red ink.
- Limitations of the study include inconsistent reporting in the literature and a small sample size, but raising awareness about tattoo-related skin cancers remains important as tattoo popularity grows.*