Real-World Pattern-of-Care Analysis of Primary Cutaneous Lymphomas Radiation Therapy Among European Organisation for Research and Treatment of Cancer Members.

Purpose: We aim to determine the current treatment patterns and recommendations among physicians for cutaneous lymphomas and to identify the types of skin lymphomas for which existing radiation regimens need improvement.

Methods And Materials: A questionnaire from the European Organisation for Research and Treatment of Cancer was distributed to all members of the Cutaneous Lymphoma Tumour Group and Radiation Oncology Scientific Council. This online survey included 13 questions regarding treatment practices for patients with cutaneous lymphoma.

Haematogenous seeding in mycosis fungoides and Sézary syndrome: Current evidence and clinical implications.

Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of diseases characterised by abnormal neoplastic T-cell growth in the skin. Mycosis fungoides (MF), the most common CTCL, manifests as erythematous skin patches and/or plaques, tumours or erythroderma. The disease may involve blood, lymph nodes and rarely viscera.

Synergistic Interactions in a Heterobimetallic Ce(III)-Ni(II) Diimine Complex: Enhancing the Electrocatalytic Efficiency for CO Reduction.

In this study, we propose a practical approach for producing a heterobimetallic Ni(II)-Ce(III) diimine complex from an extended salen-type ligand (HL) to serve as an electrocatalyst for CO reduction and demonstrate an outstanding overall efficiency of 99.6% of the cerium-nickel complex and integrate it into applicable cell assemblies. We optimize not only the catalyst, but the operational conditions enabling successful CO electrolysis over extended periods at different current densities.

QSPRpred: a Flexible Open-Source Quantitative Structure-Property Relationship Modelling Tool.

Building reliable and robust quantitative structure-property relationship (QSPR) models is a challenging task. First, the experimental data needs to be obtained, analyzed and curated. Second, the number of available methods is continuously growing and evaluating different algorithms and methodologies can be arduous.

Radiological assessment of Sella Turcica morphology correlates with skeletal classes in an Austrian population: an observational study.

Objectives: This study aimed to analyze variations in the sella turcica (ST) concerning its size, shape, and bridging, providing first reference values in Austrian individuals. Additionally, it assessed associations between these morphological and demographic parameters and their correlation with patients' skeletal class.

Methods: 208 lateral cephalometric radiographs (154 female, 54 male; age 8-58 years) from DPU Dental Clinic (Austria) were included.

Retrospective Evaluation of C-reactive Protein for Ruling Out Infection After Cesarean Section.

Introduction: Infection after cesarean section is a major contributor to maternal morbidity. Measurement of C-reactive protein (CRP) is a laboratory test frequently conducted to rule out or confirm postoperative infection. The present study aimed to evaluate whether CRP is a suitable tool for ruling out infection after cesarean section and whether there are any reliable cut-off values.

Organic Ink Multi-Material 3D Printing of Sustainable Soft Systems.

Drawing inspiration from nature, soft materials are at the core of a transformation toward adaptive and responsive engineered systems, capable of conquering demanding terrain and safe when interacting with biological life. Despite recent advances in 3D printing of soft materials, researchers are still far from being able to print complex soft systems where a multitude of different components need to work together symbiotically. Closing this gap necessitates a platform that unites diverse materials into one synergetic process.

Sodium-chloride difference is not strongly correlated with base excess in chronic kidney disease: an anion gap problem.

Introduction: The prevalence of metabolic acidosis is high in patients with chronic kidney disease (CKD). For the diagnosis, a blood gas analysis is necessary, but not always available. The aim of the study was to evaluate the base excess (BE) of the sodium-chloride difference (BE = Na-Cl-34 mmol/l) as a screening parameter for hyperchloremic metabolic acidosis.

Thrombo-CARE-cardioembolic stroke etiology in cryptogenic stroke suggested by fibrin-/platelet-rich clot histology : Thrombo-CARE (configuration analysis to refine etiology).

Background: Despite extensive diagnostic efforts, the etiology of stroke remains unclear in up to 30% of patients. Mechanical thrombectomy (MT) potentially enhances etiological determination by (immuno)histological analysis of retrieved thrombotic material.

Methods: In this monocentric exploratory study, clots from 200 patients undergoing MT were investigated by hematoxylin and eosin, CD3, and CD45 staining.

Long-Term Follow-Up After Non-Curative Endoscopic Submucosal Dissection for Early Gastrointestinal Cancer-A Retrospective Multicenter Analysis.

: Endoscopic Submucosal Dissection (ESD) has become the standard therapy for early malignant lesions in the gastrointestinal tract and has shown as good oncological surgery results. Approximately 30% of ESDs do not meet the criteria for oncological curability, and upfront surgery is indicated. Hence, about 40% of patients with an indication for surgery are advised against surgery because of comorbidities and an advanced age.

Left Atrial Appendage Closure in Atrial Fibrillation Patients with Cancer.

: There are limited data about left atrial appendage closure (LAAC) in patients with cancer. We therefore sought to compare the outcome after LAAC in patients with vs. without cancer in a multicentre registry.

Learning properties of quantum states without the IID assumption.

We develop a framework for learning properties of quantum states beyond the assumption of independent and identically distributed (i.i.d.

No difference in surgical time and total theatre time between robotically assisted and computer assisted total knee arthroplasty.

Introduction: A number of studies have demonstrated a significant reduction of surgical time for robotically assisted surgery (RAS) total knee arthroplasty (TKA) after the learning curve between 6 and 43 cases. It is unknown if the logistics of RAS produce a longer total theatre time since published literature only reflects the surgical time. It is also unknown how RAS surgical and total theatre times compare with computer assisted surgery (CAS) TKA.

Oriented artificial nanofibers and laser induced periodic surface structures as substrates for Schwann cells alignment.

People with injuries to the peripheral nervous system suffer from paralysis of the facial muscles, fingers and hands or toes and feet, often for the rest of their lives, due to its poor functional regeneration. Therefore, to improve patients' quality of life, there is an urgent need for conduits that effectively support the healing of large defects in nerve pathways through specific guidance of nerve cells. This paper describes two specific methods for achieving directed growth of Schwann cells, a type of glial cells that can support the regeneration of the nerve pathway by guiding the neuronal axons in the direction of their alignment.

Gender-Specific Differences in Recurrence and Progression following Bacillus Calmette-Guérin Instillation for Non-Muscle-Invasive Bladder Cancer.

Introduction: To assess gender-specific differences in recurrence-free survival (RFS), progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS) among patients with intermediate or high-risk non-muscle-invasive bladder cancer (NMIBC) receiving BCG was the primary aim of this systematic review and meta-analysis.

Methods: In July 2023, we performed a literature search using MEDLINE, Embase, and the Cochrane Library. This study was prospectively registered at PROSPERO (CRD 2023443269).

Multi-modal representation learning in retinal imaging using self-supervised learning for enhanced clinical predictions.

Self-supervised learning has become the cornerstone of building generalizable and transferable artificial intelligence systems in medical imaging. In particular, contrastive representation learning techniques trained on large multi-modal datasets have demonstrated impressive capabilities of producing highly transferable representations for different downstream tasks. In ophthalmology, large multi-modal datasets are abundantly available and conveniently accessible as modern retinal imaging scanners acquire both 2D fundus images and 3D optical coherence tomography (OCT) scans to assess the eye.

Dislocation and Snaring of an Aortic Bifurcation Stent During Transfemoral Aortic Valve Replacement-a Case Report.

Transfemoral aortic valve replacement (TAVR) is an effective way to treat severe aortic valve stenosis, especially in patients who are high-risk for surgery. Dislocation of an endoluminal aortic bifurcation stent graft during TAVR is an extremely rare complication. We present a case on how management of this complication was successfully done.

Innovative mobile app solution for facial nerve rehabilitation: a usability analysis.

Background: Facial palsy after vestibular schwannoma surgery is temporary in many cases but can significantly affect patients' quality of life. Physical training-initially guided and subsequently performed by the patient-is of paramount importance for recovery of facial nerve function. The introduction of medical application software (apps) might improve therapy by maintaining motivation for daily home-based training and surveilling patients' rehabilitation progress.

Oblique or short incisions reduce the risk of saphenous nerve damage during hamstrings harvesting: A model for mapping nerve pathways at the harvest site.

Introduction: Hamstring autografts are frequently used for ligament reconstruction surgery. Between 12% and 84% of patients report hypoesthesia or dysaesthesia secondary to injury of the saphenous nerve or one of its branches after hamstring harvesting. Type of incision (orientation and length) is subject of much regarding limiting the risk of nerve damage.

Modular and extendable 1D-simulation for microfluidic devices.

Microfluidic devices have been the subject of considerable attention in recent years. The development of novel microfluidic devices, their evaluation, and their validation requires simulations. While common methods based on Computational Fluid Dynamics (CFD) can be time-consuming, 1D simulation provides an appealing alternative that leads to efficient results with reasonable quality.

Unlocking the Activity of Molecular Assemblies for CO Electroreduction in Zero-Gap Electrolysers via Catalyst Ink Engineering.

In recent years, CO electrolysis, particularly the electrochemical reduction of CO to CO in zero-gap systems, has gained significant attention. While Ag-coated gas diffusion electrodes are commonly used in state-of-the-art systems, heterogenized molecular catalysts like bis-coordinated homoleptic silver(I) N,N-bis(arylimino)-acenaphthene (Ag-BIAN) complexes are emerging as a promising alternative due to their tunability and high mass activity. In this study, the influence of ink composition on the performance of Ag-BIAN-based GDEs in zero-gap electrolyzers (ZGEs) are systematically explored at 60 °C and 600 mA cm⁻.